Exploring role of 5hmC as potential marker of chemoresistance by Suhas S. Kharat, Shyam K. Sharan

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Translating Embryogenesis to Generate Organoids: Novel Approaches to Personalized Medicine by Sounak Sahu, Shyam K. Sharan

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RAD52 S346X variant reduces breast cancer risk in BRCA2 mutation carriers by Kajal Biswas, Shyam K. Sharan

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Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity by Nathan Palmer, S. Zakiah A. Talib, Christine M. F. Goh, Kajal Biswas, Shyam K. Sharan, Philipp Kaldis

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Identification PMS1 and PMS2 as potential meiotic substrates of CDK2 activity. by Nathan Palmer, S Zakiah A Talib, Christine M F Goh, Kajal Biswas, Shyam K Sharan, Philipp Kaldis

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Functional evaluation of five BRCA2 unclassified variants identified in a Sri Lankan cohort with inherited cancer syndromes using a mouse embryonic stem cell-based assay by Nirmala Sirisena, Kajal Biswas, Teresa Sullivan, Stacey Stauffer, Linda Cleveland, Eileen Southon, Vajira H. W. Dissanayake, Shyam K. Sharan

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Growth factor dependency in mammary organoids regulates ductal morphogenesis during organ regeneration by Sounak Sahu, Mary E. Albaugh, Betty K. Martin, Nimit L. Patel, Lisa Riffle, Susan Mackem, Joseph D. Kalen, Shyam K. Sharan

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A computational model for classification of BRCA2 variants using mouse embryonic stem cell-based functional assays by Kajal Biswas, Gary B. Lipton, Stacey Stauffer, Teresa Sullivan, Linda Cleveland, Eileen Southon, Susan Reid, Valentin Magidson, Edwin S. Iversen, Shyam K. Sharan

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Interaction with PALB2 Is Essential for Maintenance of Genomic Integrity by BRCA2. by Suzanne A Hartford, Rajanikant Chittela, Xia Ding, Aradhana Vyas, Betty Martin, Sandra Burkett, Diana C Haines, Eileen Southon, Lino Tessarollo, Shyam K Sharan

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BRE/BRCC45 regulates CDC25A stability by recruiting USP7 in response to DNA damage by Kajal Biswas, Subha Philip, Aditya Yadav, Betty K. Martin, Sandra Burkett, Vaibhav Singh, Anav Babbar, Susan Lynn North, Suhwan Chang, Shyam K. Sharan

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The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation by Xiaoping Xu, Kai Ni, Yafeng He, Jianke Ren, Chongkui Sun, Yie Liu, Mirit I. Aladjem, Sandra Burkett, Richard Finney, Xia Ding, Shyam K. Sharan, Kathrin Muegge

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Interferon restores replication fork stability and cell viability in BRCA-defective cells via ISG15 by Ramona N. Moro, Uddipta Biswas, Suhas S. Kharat, Filip D. Duzanic, Prosun Das, Maria Stavrou, Maria C. Raso, Raimundo Freire, Arnab Ray Chaudhuri, Shyam K. Sharan, Lorenza Penengo

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WRN helicase safeguards deprotected replication forks in BRCA2-mutated cancer cells by Arindam Datta, Kajal Biswas, Joshua A. Sommers, Haley Thompson, Sanket Awate, Claudia M. Nicolae, Tanay Thakar, George-Lucian Moldovan, Robert H. Shoemaker, Shyam K. Sharan, Robert M. Brosh

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Saturation genome editing of 11 codons and exon 13 of BRCA2 coupled with chemotherapeutic drug response accurately determines pathogenicity of variants. by Sounak Sahu, Teresa L Sullivan, Alexander Y Mitrophanov, Mélissa Galloux, Darryl Nousome, Eileen Southon, Dylan Caylor, Arun Prakash Mishra, Christine N Evans, Michelle E Clapp, Sandra Burkett, Tyler Malys, Raj Chari, Kajal Biswas, Shyam K Sharan

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Characterization of BRCA2 R3052Q variant in mice supports its functional impact as a low-risk variant by Arun Prakash Mishra, Suzanne Hartford, Rajani Kant Chittela, Sounak Sahu, Suhas S. Kharat, Lucia Alvaro-Aranda, Aida Contreras-Perez, Teresa Sullivan, Betty K. Martin, Mary Albaugh, Eileen Southon, Sandra Burkett, Baktiar Karim, Aura Carreira, Lino Tessarollo, Shyam K. Sharan

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Sequencing-based functional assays for classification of BRCA2 variants in mouse ESCs by Kajal Biswas, Alexander Y. Mitrophanov, Sounak Sahu, Teresa Sullivan, Eileen Southon, Darryl Nousome, Susan Reid, Sakshi Narula, Julia Smolen, Trisha Sengupta, Maximilian Riedel-Topper, Medha Kapoor, Anav Babbar, Stacey Stauffer, Linda Cleveland, Mayank Tandon, Tyler Malys, Shyam K. Sharan

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A novel mouse model of PMS2 founder mutation that causes mismatch repair defect due to aberrant splicing by Kajal Biswas, Martin Couillard, Luca Cavallone, Sandra Burkett, Stacey Stauffer, Betty K. Martin, Eileen Southon, Susan Reid, Teri M. Plona, Ryan N. Baugher, Stephanie D. Mellott, Kristen M. Pike, Mary E. Albaugh, Chelsea Maedler-Kron, Nancy Hamel, Lino Tessarollo, Victoria Marcus, William D. Foulkes, Shyam K. Sharan

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