Nonfucosylation of an anti-TIGIT antibody enhances FcγR engagement, driving innate immune activation and antitumor activity by Alyson J. Smith, Robert E. Thurman, Weiping Zeng, Bryan Grogan, Sasha Lucas, Guadalupe Gutierrez, Ryan A. Heiser, Serena W. Wo, Amber Blackmarr, Scott Peterson, Shyra J. Gardai

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Systems-based analyses of brain regions functionally impacted in Parkinson's disease reveals underlying causal mechanisms. by Brigit E Riley, Shyra J Gardai, Dorothea Emig-Agius, Marina Bessarabova, Alexander E Ivliev, Birgitt Schüle, Jeff Alexander, William Wallace, Glenda M Halliday, J William Langston, Scott Braxton, Ted Yednock, Thomas Shaler, Jennifer A Johnston

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SGN-B7H4V, an investigational vedotin ADC directed to the immune checkpoint ligand B7-H4, shows promising activity in preclinical models by Elizabeth Gray, Kelly Hensley, Sean Allred, Robert Thurman, Katie Snead, Michelle Ulrich, Dannah Miller, Serena Wo, Angela Epp, Disha Sahetya, Julie Hahn, Chris Frantz, Natalya Nazarenko, Kellie Spahr, Patrick Younan, Li-Ya Huang, Kristen Gahnberg, Piper M Treuting, Esther S Trueblood, John J Gosink, Evgenia Jane Haass, Mary Padilla, Alyson J Smith, Jason P Schrum, Shyra J Gardai

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Targeting the intrinsically disordered structural ensemble of α-synuclein by small molecules as a potential therapeutic strategy for Parkinson's disease. by Gergely Tóth, Shyra J Gardai, Wagner Zago, Carlos W Bertoncini, Nunilo Cremades, Susan L Roy, Mitali A Tambe, Jean-Christophe Rochet, Celine Galvagnion, Gaia Skibinski, Steven Finkbeiner, Michael Bova, Karin Regnstrom, San-San Chiou, Jennifer Johnston, Kari Callaway, John P Anderson, Michael F Jobling, Alexander K Buell, Ted A Yednock, Tuomas P J Knowles, Michele Vendruscolo, John Christodoulou, Christopher M Dobson, Dale Schenk, Lisa McConlogue

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