Preface: Special issue on challenges and new findings on misused psychoactive drugs by Silvia L. Cruz

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Fentanyl and other new psychoactive synthetic opioids. Challenges to prevention and treatment by Damaris Albores-García, Silvia L. Cruz

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Methadone Requires the Co-Activation of μ-Opioid and Toll-Like-4 Receptors to Produce Extracellular DNA Traps in Bone-Marrow-Derived Mast Cells by Frida L. Martínez-Cuevas, Silvia L. Cruz, Claudia González-Espinosa

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Amphetamine-type stimulants: Novel insights into their actions and use patterns by Miguel I. Paz-Ramos, Silvia L. Cruz, Valeria Violante-Soria

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First drug-checking study at an electronic festival and fentanyl detection in the central region of Mexico by Silvia L. Cruz, Miguel Bencomo-Cruz, María E. Medina-Mora, Fabiola Vázquez-Quiroz, Clara Fleiz-Bautista

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Endocannabinoid modulation of allergic responses: Focus on the control of FcεRI-mediated mast cell activation by Rubi Monserrat Osorio-Perez, Gabriela Rodríguez-Manzo, Zyanya P. Espinosa-Riquer, Silvia L. Cruz, Claudia González-Espinosa

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