Treatment with TNF‐α inhibitors versus methotrexate and the association with dementia and Alzheimer's disease by David M. Kern, Simon Lovestone, M. Soledad Cepeda

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Glycosylated clusterin species facilitate Aβ toxicity in human neurons by Evangeline M. Foster, Marco Fernandes, Adria Dangla-Valls, Philip Hublitz, Menelaos Pangalos, Simon Lovestone, Elena M. Ribe, Noel J. Buckley

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Genetic and Real-World Clinical Data, Combined with Empirical Validation, Nominate Jak-Stat Signaling as a Target for Alzheimer’s Disease Therapeutic Development by Alejo J. Nevado-Holgado, Elena Ribe, Laura Thei, Laura Furlong, Miguel-Angel Mayer, Jie Quan, Jill C. Richardson, Jonathan Cavanagh, NIMA Consortium, Simon Lovestone

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease by Marta Vicente-Rodríguez, Renzo Mancuso, Alba Peris-Yague, Camilla Simmons, NIMA Consortium, Diego Gómez-Nicola, V. Hugh Perry, Federico Turkheimer, Simon Lovestone, Christine A. Parker, Diana Cash

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Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants by Karen Y. He, Ekaterina A. Khramtsova, Alfredo Cabrera-Socorro, Yanfei Zhang, Shuwei Li, Brice A. J. Sarver, Bart Smets, Qingqin S. Li, Louis De Muynck, Antonio R. Parrado, Simon Lovestone, Mary Helen Black

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Identification of plasma proteins relating to brain neurodegeneration and vascular pathology in cognitively normal individuals by Liu Shi, Colin R. Buchanan, Simon R. Cox, Robert F. Hillary, Riccardo E. Marioni, Archie Campbell, Caroline Hayward, Aleks Stolicyn, Heather C. Whalley, Mathew A. Harris, Jennifer Waymont, Gordon Waiter, Ellen Backhouse, Joanna M. Wardlaw, Douglas Steele, Andrew Mcintosh, Simon Lovestone, Noel J. Buckley, Alejo J. Nevado‐Holgado

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CSF Proteomic Alzheimer’s Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals by Betty Marije Tijms, Johan Gobom, Charlotte Teunissen, Valerija Dobricic, Magda Tsolaki, Frans Verhey, Julius Popp, Pablo Martinez-Lage, Rik Vandenberghe, Alberto Lleó, José Luís Molinuévo, Sebastiaan Engelborghs, Yvonne Freund-Levi, Lutz Froelich, Lars Bertram, Simon Lovestone, Johannes Streffer, Stephanie Vos, ADNI, Kaj Blennow, Philip Scheltens, Henrik Zetterberg, Pieter Jelle Visser

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Multivariate GWAS of Alzheimer’s disease CSF biomarker profiles implies GRIN2D in synaptic functioning by Alexander Neumann, Olena Ohlei, Fahri Küçükali, Isabelle J. Bos, Jigyasha Timsina, Stephanie Vos, Dmitry Prokopenko, Betty M. Tijms, Ulf Andreasson, Kaj Blennow, Rik Vandenberghe, Philip Scheltens, Charlotte E. Teunissen, Sebastiaan Engelborghs, Giovanni B. Frisoni, Oliver Blin, Jill C. Richardson, Régis Bordet, Alberto Lleó, Daniel Alcolea, Julius Popp, Thomas W. Marsh, Priyanka Gorijala, Christopher Clark, Gwendoline Peyratout, Pablo Martinez-Lage, Mikel Tainta, Richard J. B. Dobson, Cristina Legido-Quigley, Christine Van Broeckhoven, Rudolph E. Tanzi, Mara ten Kate, Christina M. Lill, Frederik Barkhof, Carlos Cruchaga, Simon Lovestone, Johannes Streffer, Henrik Zetterberg, Pieter Jelle Visser, Kristel Sleegers, Lars Bertram, EMIF-AD & ADNI study group

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Sex-Specific Metabolic Pathways Were Associated with Alzheimer’s Disease (AD) Endophenotypes in the European Medical Information Framework for AD Multimodal Biomarker Discovery Coh... by Jin Xu, Rebecca Green, Min Kim, Jodie Lord, Amera Ebshiana, Sarah Westwood, Alison L. Baird, Alejo J. Nevado-Holgado, Liu Shi, Abdul Hye, Stuart G. Snowden, Isabelle Bos, Stephanie J. B. Vos, Rik Vandenberghe, Charlotte E. Teunissen, Mara Ten Kate, Philip Scheltens, Silvy Gabel, Karen Meersmans, Olivier Blin, Jill Richardson, Ellen Elisa De Roeck, Sebastiaan Engelborghs, Kristel Sleegers, Régis Bordet, Lorena Rami, Petronella Kettunen, Magda Tsolaki, Frans R. J. Verhey, Daniel Alcolea, Alberto Lleó, Gwendoline Peyratout, Mikel Tainta, Peter Johannsen, Yvonne Freund-Levi, Lutz Frölich, Valerija Dobricic, Giovanni B. Frisoni, José Luis Molinuevo, Anders Wallin, Julius Popp, Pablo Martinez-Lage, Lars Bertram, Kaj Blennow, Henrik Zetterberg, Johannes Streffer, Pieter Jelle Visser, Simon Lovestone, Petroula Proitsi, Cristina Legido-Quigley, on behalf of the European Medical Information Framework Consortium

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