Genetics and Molecular Basis of Congenital Heart Defects in Down Syndrome: Role of Extracellular Matrix Regulation by Nunzia Mollo, Roberta Scognamiglio, Anna Conti, Simona Paladino, Lucio Nitsch, Antonella Izzo

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Targeting Heparan Sulfate Proteoglycans as a Novel Therapeutic Strategy for Mucopolysaccharidoses by Valeria De Pasquale, Patrizia Sarogni, Valeria Pistorio, Giuliana Cerulo, Simona Paladino, Luigi Michele Pavone

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Identification of sumoylation sites in CCDC6, the first identified RET partner gene in papillary thyroid carcinoma, uncovers a mode of regulating CCDC6 function on CREB1 transcript... by Chiara Luise, Francesco Merolla, Vincenza Leone, Simona Paladino, Daniela Sarnataro, Alfredo Fusco, Angela Celetti

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Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo by Anna Pepe, Rosario Avolio, Danilo Swann Matassa, Franca Esposito, Lucio Nitsch, Chiara Zurzolo, Simona Paladino, Daniela Sarnataro

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Targeting Mitochondrial Network Architecture in Down Syndrome and Aging by Nunzia Mollo, Rita Cicatiello, Miriam Aurilia, Roberta Scognamiglio, Rita Genesio, Maria Charalambous, Simona Paladino, Anna Conti, Lucio Nitsch, Antonella Izzo

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Phenotypic Effects of Homeodomain-Interacting Protein Kinase 2 Deletion in Mice by Davide De Biase, Valeria Valente, Andrea Conte, Francesca Cammarota, Nicola Boccella, Lucia D’Esposito, Ilaria d’Aquino, Orlando Paciello, Simona Paladino, Giovanna Maria Pierantoni

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Bone marrow mesenchymal stem cells as a possible ruxolitinib reservoir in the bone marrow niche by Luigi Marino, Bruno Charlier, Valentina Giudice, Paolo Remondelli, Simona Paladino, Rosa Vitolo, Fabrizio Dal Piaz, Barbara Izzo, Pio Zeppa, Viviana Izzo, Amelia Filippelli, Carmine Selleri

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Overexpression of the Hsa21 Transcription Factor RUNX1 Modulates the Extracellular Matrix in Trisomy 21 Cells by Nunzia Mollo, Miriam Aurilia, Roberta Scognamiglio, Lucrezia Zerillo, Rita Cicatiello, Ferdinando Bonfiglio, Ferdinando Bonfiglio, Pasqualina Pagano, Simona Paladino, Anna Conti, Lucio Nitsch, Lucio Nitsch, Antonella Izzo

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Cholesterol Homeostasis Modulates Platinum Sensitivity in Human Ovarian Cancer by Daniela Criscuolo, Rosario Avolio, Giovanni Calice, Chiara Laezza, Simona Paladino, Giovanna Navarra, Francesca Maddalena, Fabiana Crispo, Cristina Pagano, Maurizio Bifulco, Matteo Landriscina, Danilo Swann Matassa, Franca Esposito

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Fighting the Huntington’s Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies... by Claudia Riccardi, Federica D’Aria, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Dominga Fasano, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola

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Truncated Analogues of a G-Quadruplex-Forming Aptamer Targeting Mutant Huntingtin: Shorter Is Better! by Claudia Riccardi, Federica D’Aria, Dominga Fasano, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola

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Cocoa Extract Provides Protection against 6-OHDA Toxicity in SH-SY5Y Dopaminergic Neurons by Targeting PERK by Vincenzo Vestuto, Giuseppina Amodio, Giacomo Pepe, Manuela Giovanna Basilicata, Raffaella Belvedere, Enza Napolitano, Daniela Guarnieri, Valentina Pagliara, Simona Paladino, Manuela Rodriquez, Alessia Bertamino, Pietro Campiglia, Paolo Remondelli, Ornella Moltedo

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Chronic exposure to l-BMAA cyanotoxin induces cytoplasmic TDP-43 accumulation and glial activation, reproducing an amyotrophic lateral sclerosis-like phenotype in mice by Serenella Anzilotti, Valeria Valente, Paola Brancaccio, Cristina Franco, Antonella Casamassa, Giovanna Lombardi, Alessandra Palazzi, Andrea Conte, Simona Paladino, Lorella Maria Teresa Canzoniero, Lucio Annunziato, Giovanna Maria Pierantoni, Giuseppe Pignataro

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Genotype-Phenotype Correlations in Neurofibromatosis Type 1: Identification of Novel and Recurrent <i>NF1</i> Gene Variants and Correlations with Neurocognitive Phenotype by Filomena Napolitano, Milena Dell’Aquila, Chiara Terracciano, Giuseppina Franzese, Maria Teresa Gentile, Giulio Piluso, Claudia Santoro, Davide Colavito, Anna Patanè, Paolo De Blasiis, Simone Sampaolo, Simona Paladino, Mariarosa Anna Beatrice Melone

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PD-1 blockade delays tumor growth by inhibiting an intrinsic SHP2/Ras/MAPK signalling in thyroid cancer cells by Federica Liotti, Narender Kumar, Nella Prevete, Maria Marotta, Daniela Sorriento, Caterina Ieranò, Andrea Ronchi, Federica Zito Marino, Sonia Moretti, Renato Colella, Efiso Puxeddu, Simona Paladino, Yoshihito Kano, Michael Ohh, Stefania Scala, Rosa Marina Melillo

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Human Trisomic iPSCs from Down Syndrome Fibroblasts Manifest Mitochondrial Alterations Early during Neuronal Differentiation by Nunzia Mollo, Matteo Esposito, Miriam Aurilia, Roberta Scognamiglio, Rossella Accarino, Ferdinando Bonfiglio, Rita Cicatiello, Maria Charalambous, Claudio Procaccini, Teresa Micillo, Rita Genesio, Gaetano Calì, Agnese Secondo, Simona Paladino, Giuseppe Matarese, Gabriella De Vita, Anna Conti, Lucio Nitsch, Antonella Izzo

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The thyroid hormone activating enzyme, type 2 deiodinase, induces myogenic differentiation by regulating mitochondrial metabolism and reducing oxidative stress by Serena Sagliocchi, Annunziata Gaetana Cicatiello, Emery Di Cicco, Raffaele Ambrosio, Caterina Miro, Daniela Di Girolamo, Annarita Nappi, Giuseppina Mancino, Maria Angela De Stefano, Cristina Luongo, Maddalena Raia, Ashley N. Ogawa-Wong, Ann Marie Zavacki, Simona Paladino, Domenico Salvatore, Monica Dentice

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Down Syndrome Fetal Fibroblasts Display Alterations of Endosomal Trafficking Possibly due to SYNJ1 Overexpression by Laura De Rosa, Dominga Fasano, Dominga Fasano, Lucrezia Zerillo, Valeria Valente, Antonella Izzo, Nunzia Mollo, Giuseppina Amodio, Elena Polishchuk, Roman Polishchuk, Mariarosa Anna Beatrice Melone, Chiara Criscuolo, Anna Conti, Lucio Nitsch, Lucio Nitsch, Paolo Remondelli, Giovanna Maria Pierantoni, Simona Paladino

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Pioglitazone Improves Mitochondrial Organization and Bioenergetics in Down Syndrome Cells by Nunzia Mollo, Maria Nitti, Maria Nitti, Lucrezia Zerillo, Deriggio Faicchia, Teresa Micillo, Rossella Accarino, Agnese Secondo, Tiziana Petrozziello, Gaetano Calì, Rita Cicatiello, Ferdinando Bonfiglio, Viviana Sarnataro, Rita Genesio, Antonella Izzo, Paolo Pinton, Giuseppe Matarese, Giuseppe Matarese, Simona Paladino, Anna Conti, Lucio Nitsch, Lucio Nitsch

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PERK-Mediated Unfolded Protein Response Activation and Oxidative Stress in PARK20 Fibroblasts by Giuseppina Amodio, Ornella Moltedo, Dominga Fasano, Lucrezia Zerillo, Marco Oliveti, Paola Di Pietro, Raffaella Faraonio, Paolo Barone, Maria Teresa Pellecchia, Anna De Rosa, Giuseppe De Michele, Elena Polishchuk, Roman Polishchuk, Vincenzo Bonifati, Lucio Nitsch, Giovanna Maria Pierantoni, Maurizio Renna, Chiara Criscuolo, Simona Paladino, Paolo Remondelli

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