Current Landscape and Future Direction of PD-1/PD-L1 Checkpoint Inhibitors in Cancer Treatment by Simona Serratì, Francesca Margheri

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The Fast Track for Intestinal Tumor Cell Differentiation and In Vitro Intestinal Models by Inorganic Topographic Surfaces by Matteo Centonze, Erwin J. W. Berenschot, Simona Serrati, Arturo Susarrey-Arce, Silke Krol

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Salting-Out Approach Is Worthy of Comparison with Ultracentrifugation for Extracellular Vesicle Isolation from Tumor and Healthy Models by Simona Serratì, Antonio Palazzo, Annamaria Lapenna, Helena Mateos, Antonia Mallardi, René Massimiliano Marsano, Alessandra Quarta, Mario Del Rosso, Amalia Azzariti

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The ERRα–VDR axis promotes calcitriol degradation and estrogen signaling in breast cancer cells, while VDR‐CYP24A1‐ERRα overexpression correlates with poor prognosis in patients wi... by Katia Danza, Letizia Porcelli, Simona De Summa, Roberta Di Fonte, Brunella Pilato, Rosanna Lacalamita, Simona Serratì, Amalia Azzariti, Stefania Tommasi

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Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6. by Chiara Donati, Giuseppina Marseglia, Alberto Magi, Simona Serratì, Francesca Cencetti, Caterina Bernacchioni, Genni Nannetti, Matteo Benelli, Silvia Brunelli, Francesca Torricelli, Giulio Cossu, Paola Bruni

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CAFs and TGF-β Signaling Activation by Mast Cells Contribute to Resistance to Gemcitabine/Nabpaclitaxel in Pancreatic Cancer by Letizia Porcelli, Rosa Maria Iacobazzi, Roberta Di Fonte, Simona Serratì, Angelica Intini, Antonio Giovanni Solimando, Oronzo Brunetti, Angela Calabrese, Francesco Leonetti, Amalia Azzariti, Nicola Silvestris

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EGFR/uPAR interaction as druggable target to overcome vemurafenib acquired resistance in melanoma cellsResearch in context by Anna Laurenzana, Francesca Margheri, Alessio Biagioni, Anastasia Chillà, Nicola Pimpinelli, Jessica Ruzzolini, Silvia Peppicelli, Elena Andreucci, Lido Calorini, Simona Serratì, Mario Del Rosso, Gabriella Fibbi

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Cervical cancer benefits from trabectedin combination with the β-blocker propranolol: in vitro and ex vivo evaluations in patient-derived organoids by Roberta Di Fonte, Sabino Strippoli, Marianna Garofoli, Gennaro Cormio, Simona Serratì, Vera Loizzi, Rossella Fasano, Francesca Arezzo, Mariateresa Volpicella, Afshin Derakhshani, Michele Guida, Letizia Porcelli, Amalia Azzariti

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Tomatine Displays Antitumor Potential in In Vitro Models of Metastatic Melanoma by Simona Serratì, Letizia Porcelli, Stefania Guida, Anna Ferretta, Rosa Maria Iacobazzi, Tiziana Cocco, Immacolata Maida, Gabriella Tamasi, Claudio Rossi, Michele Manganelli, Stefania Tommasi, Amalia Azzariti, Gabriella Guida

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Challenges and Opportunities of MicroRNAs in Lymphomas by Giacoma De Tullio, Vincenza De Fazio, Nicola Sgherza, Carla Minoia, Simona Serratì, Francesca Merchionne, Giacomo Loseto, Angela Iacobazzi, Antonello Rana, Patrizia Petrillo, Nicola Silvestris, Pasquale Iacopino, Attilio Guarini

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Circulating extracellular vesicles expressing PD1 and PD-L1 predict response and mediate resistance to checkpoint inhibitors immunotherapy in metastatic melanoma by Simona Serratì, Michele Guida, Roberta Di Fonte, Simona De Summa, Sabino Strippoli, Rosa Maria Iacobazzi, Alessandra Quarta, Ivana De Risi, Gabriella Guida, Angelo Paradiso, Letizia Porcelli, Amalia Azzariti

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miR-214-Enriched Extracellular Vesicles Released by Acid-Adapted Melanoma Cells Promote Inflammatory Macrophage-Dependent Tumor Trans-Endothelial Migration by Elena Andreucci, Jessica Ruzzolini, Francesca Bianchini, Giampaolo Versienti, Alessio Biagioni, Matteo Lulli, Daniele Guasti, Patrizia Nardini, Simona Serratì, Francesca Margheri, Anna Laurenzana, Chiara Nediani, Silvia Peppicelli, Lido Calorini

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GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides. by Francesca Margheri, Nicola Schiavone, Laura Papucci, Lucia Magnelli, Simona Serratì, Anastasia Chillà, Anna Laurenzana, Francesca Bianchini, Lido Calorini, Eugenio Torre, Javier Dotor, Esperanza Feijoo, Gabriella Fibbi, Mario Del Rosso

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Correction: Desmoglein-2-Integrin Beta-8 Interaction Regulates Actin Assembly in Endothelial Cells: Deregulation in Systemic Sclerosis. by Betti Giusti, Francesca Margheri, Luciana Rossi, Ilaria Lapini, Alberto Magi, Simona Serratì, Anastasia Chillà, Anna Laurenzana, Lucia Magnelli, Lido Calorini, Francesca Bianchini, Gabriella Fibbi, Rosanna Abbate, Mario Del Rosso

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Microfluidic-Assisted Preparation of Targeted pH-Responsive Polymeric Micelles Improves Gemcitabine Effectiveness in PDAC: In Vitro Insights by Rosa Maria Iacobazzi, Ilaria Arduino, Roberta Di Fonte, Angela Assunta Lopedota, Simona Serratì, Giuseppe Racaniello, Viviana Bruno, Valentino Laquintana, Byung-Chul Lee, Nicola Silvestris, Francesco Leonetti, Nunzio Denora, Letizia Porcelli, Amalia Azzariti

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Circulating extracellular vesicles are monitoring biomarkers of anti-PD1 response and enhancer of tumor progression and immunosuppression in metastatic melanoma by Simona Serratì, Roberta Di Fonte, Letizia Porcelli, Simona De Summa, Ivana De Risi, Livia Fucci, Eustachio Ruggieri, Tommaso Maria Marvulli, Sabino Strippoli, Rossella Fasano, Tania Rafaschieri, Gabriella Guida, Michele Guida, Amalia Azzariti

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Reproducibility warning: The curious case of polyethylene glycol 6000 and spheroid cell culture. by Simona Serrati, Chiara Martinelli, Antonio Palazzo, Rosa Maria Iacobazzi, Mara Perrone, Quy K Ong, Zhi Luo, Ahmet Bekdemir, Giulia Pinto, Ornella Cavalleri, Annalisa Cutrignelli, Valentino Laquintana, Nunzio Denora, Francesco Stellacci, Silke Krol

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Hydroxy-Propil-β-Cyclodextrin Inclusion Complexes of two Biphenylnicotinamide Derivatives: Formulation and Anti-Proliferative Activity Evaluation in Pancreatic Cancer Cell Models by Rosa Maria Iacobazzi, Annalisa Cutrignelli, Angela Stefanachi, Letizia Porcelli, Angela Assunta Lopedota, Roberta Di Fonte, Antonio Lopalco, Simona Serratì, Valentino Laquintana, Nicola Silvestris, Massimo Franco, Saverio Cellamare, Francesco Leonetti, Amalia Azzariti, Nunzio Denora

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The Interaction between Reactive Peritoneal Mesothelial Cells and Tumor Cells via Extracellular Vesicles Facilitates Colorectal Cancer Dissemination by Simona Serratì, Letizia Porcelli, Francesco Fragassi, Marianna Garofoli, Roberta Di Fonte, Livia Fucci, Rosa Maria Iacobazzi, Antonio Palazzo, Francesca Margheri, Grazia Cristiani, Anna Albano, Raffaele De Luca, Donato Francesco Altomare, Michele Simone, Amalia Azzariti

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