Molecular Testing in CML between Old and New Methods: Are We at a Turning Point? by Simona Soverini, Simona Bernardi, Sara Galimberti

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Treatment and monitoring of Philadelphia chromosome-positive leukemia patients: recent advances and remaining challenges by Simona Soverini, Renato Bassan, Thomas Lion

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Chronic myeloid leukemia: the paradigm of targeting oncogenic tyrosine kinase signaling and counteracting resistance for successful cancer therapy by Simona Soverini, Manuela Mancini, Luana Bavaro, Michele Cavo, Giovanni Martinelli

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Current treatment approaches in CML by Fausto Castagnetti, Gabriele Gugliotta, Simona Soverini, Michele Baccarani, Gianantonio Rosti

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Chronic Myeloid Leukemia Prognosis and Therapy: Criticisms and Perspectives by Domenico Russo, José Valentín Garcia-Gutierrez, Simona Soverini, Michele Baccarani

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Targeting Leukemic Stem Cells in Chronic Myeloid Leukemia: Is It Worth the Effort? by Simona Soverini, Sara De Santis, Cecilia Monaldi, Samantha Bruno, Manuela Mancini

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Aurora kinase inhibitors: which role in the treatment of chronic myelogenous leukemia patients resistant to imatinib? by Giovanni Martinelli, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Daniela Cilloni, Michele Baccarani

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The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities by Samantha Bruno, Manuela Mancini, Sara De Santis, Cecilia Monaldi, Michele Cavo, Simona Soverini

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CDC20 in and out of mitosis: a prognostic factor and therapeutic target in hematological malignancies by Samantha Bruno, Andrea Ghelli Luserna di Rorà, Roberta Napolitano, Simona Soverini, Giovanni Martinelli, Giorgia Simonetti

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Recent Advances in the Molecular Biology of Systemic Mastocytosis: Implications for Diagnosis, Prognosis, and Therapy by Margherita Martelli, Cecilia Monaldi, Sara De Santis, Samantha Bruno, Manuela Mancini, Michele Cavo, Simona Soverini

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Combined Inhibition of Polo-Like Kinase-1 and Wee1 as a New Therapeutic Strategy to Induce Apoptotic Cell Death in Neoplastic Mast Cells by Manuela Mancini, Cecilia Monaldi, Sara De Santis, Michela Rondoni, Cristina Papayannidis, Chiara Sartor, Antonio Curti, Samantha Bruno, Michele Cavo, Simona Soverini

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Assessing Measurable Residual Disease in Chronic Myeloid Leukemia. BCR-ABL1 IS in the Avant-Garde of Molecular Hematology by Vlad Moisoiu, Patric Teodorescu, Patric Teodorescu, Lorand Parajdi, Sergiu Pasca, Mihnea Zdrenghea, Delia Dima, Radu Precup, Ciprian Tomuleasa, Ciprian Tomuleasa, Simona Soverini

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14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia. by Manuela Mancini, Elisa Leo, Ken-Ichi Takemaru, Virginia Campi, Fausto Castagnetti, Simona Soverini, Caterina De Benedittis, Gianantonio Rosti, Michele Cavo, Maria Alessandra Santucci, Giovanni Martinelli

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Prognosis in Chronic Myeloid Leukemia: Baseline Factors, Dynamic Risk Assessment and Novel Insights by Miriam Iezza, Sofia Cortesi, Emanuela Ottaviani, Manuela Mancini, Claudia Venturi, Cecilia Monaldi, Sara De Santis, Nicoletta Testoni, Simona Soverini, Gianantonio Rosti, Michele Cavo, Fausto Castagnetti

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Polo-like kinase-1, Aurora kinase A and WEE1 kinase are promising druggable targets in CML cells displaying BCR::ABL1-independent resistance to tyrosine kinase inhibitors by Manuela Mancini, Sara De Santis, Cecilia Monaldi, Fausto Castagnetti, Fausto Castagnetti, Annalisa Lonetti, Samantha Bruno, Elisa Dan, Barbara Sinigaglia, Barbara Sinigaglia, Gianantonio Rosti, Michele Cavo, Michele Cavo, Gabriele Gugliotta, Simona Soverini

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Next-generation sequencing for BCR-ABL1 kinase domain mutation testing in patients with chronic myeloid leukemia: a position paper by Simona Soverini, Elisabetta Abruzzese, Monica Bocchia, Massimiliano Bonifacio, Sara Galimberti, Antonella Gozzini, Alessandra Iurlo, Luigiana Luciano, Patrizia Pregno, Gianantonio Rosti, Giuseppe Saglio, Fabio Stagno, Mario Tiribelli, Paolo Vigneri, Giovanni Barosi, Massimo Breccia

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SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted by Manuela Mancini, Cecilia Monaldi, Sara De Santis, Cristina Papayannidis, Michela Rondoni, Chiara Sartor, Samantha Bruno, Livio Pagano, Marianna Criscuolo, Roberta Zanotti, Massimiliano Bonifacio, Patrizia Tosi, Michel Arock, Peter Valent, Michele Cavo, Simona Soverini

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Pharmacological Inhibition of WIP1 Sensitizes Acute Myeloid Leukemia Cells to the MDM2 Inhibitor Nutlin-3a by Maria Chiara Fontana, Jacopo Nanni, Andrea Ghelli Luserna di Rorà, Elisabetta Petracci, Antonella Padella, Martina Ghetti, Anna Ferrari, Giovanni Marconi, Simona Soverini, Ilaria Iacobucci, Cristina Papayannidis, Antonio Curti, Ernesta Audisio, Maria Benedetta Giannini, Michela Rondoni, Francesco Lanza, Michele Cavo, Giovanni Martinelli, Giorgia Simonetti

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Case Report: A Novel Activating FLT3 Mutation in Acute Myeloid Leukemia by Samantha Bruno, Lorenza Bandini, Agnese Patuelli, Valentina Robustelli, Valentina Robustelli, Claudia Venturi, Manuela Mancini, Dorian Forte, Sara De Santis, Cecilia Monaldi, Alessandra Grassi, Gabriella Chiurumbolo, Stefania Paolini, Gianluca Cristiano, Cristina Papayannidis, Chiara Sartor, Jacopo Nanni, Emanuela Ottaviani, Antonio Curti, Michele Cavo, Michele Cavo, Simona Soverini

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