Prion propagation and cellular dysfunction in prion disease: Disconnecting the dots by Simote T. Foliaki, Cathryn L. Haigh

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Prion propagation and cellular dysfunction in prion disease: Disconnecting the dots. by Simote T Foliaki, Cathryn L Haigh

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Reduced SOD2 expression does not influence prion disease course or pathology in mice by Simote T. Foliaki, Brent Race, Katie Williams, Chase Baune, Bradley R. Groveman, Cathryn L. Haigh

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Neural cell engraftment therapy for sporadic Creutzfeldt-Jakob disease restores neuroelectrophysiological parameters in a cerebral organoid model by Katie Williams, Simote T. Foliaki, Brent Race, Anna Smith, Tina Thomas, Bradley R. Groveman, Cathryn L. Haigh

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Pathogenic Prion Protein Isoforms Are Not Present in Cerebral Organoids Generated from Asymptomatic Donors Carrying the E200K Mutation Associated with Familial Prion Disease by Simote T. Foliaki, Bradley R. Groveman, Jue Yuan, Ryan Walters, Shulin Zhang, Paul Tesar, Wenquan Zou, Cathryn L. Haigh

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Sporadic Creutzfeldt–Jakob disease infected human cerebral organoids retain the original human brain subtype features following transmission to humanized transgenic mice by Bradley R. Groveman, Brent Race, Simote T. Foliaki, Katie Williams, Andrew G. Hughson, Chase Baune, Gianluigi Zanusso, Cathryn L. Haigh

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Temporary alteration of neuronal network communication is a protective response to redox imbalance that requires GPI-anchored prion protein by Simote T. Foliaki, Aleksandar Wood, Katie Williams, Anna Smith, Ryan O. Walters, Chase Baune, Bradley R. Groveman, Cathryn L. Haigh

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Hereditary E200K mutation within the prion protein gene alters human iPSC derived cardiomyocyte function by Aleksandar R. Wood, Simote T. Foliaki, Bradley R. Groveman, Ryan O. Walters, Katie Williams, Jue Yuan, Wen-Quan Zou, Cathryn L. Haigh

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Stress and viral insults do not trigger E200K PrP conversion in human cerebral organoids. by Anna Smith, Bradley R Groveman, Clayton Winkler, Katie Williams, Ryan Walters, Jue Yuan, Wenquan Zou, Karin Peterson, Simote T Foliaki, Cathryn L Haigh

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Human cerebral organoids as a therapeutic drug screening model for Creutzfeldt–Jakob disease by Bradley R. Groveman, Natalia C. Ferreira, Simote T. Foliaki, Ryan O. Walters, Clayton W. Winkler, Brent Race, Andrew G. Hughson, Gianluigi Zanusso, Cathryn L. Haigh

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Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction. by Simote T Foliaki, Anna Smith, Benjamin Schwarz, Eric Bohrnsen, Catharine M Bosio, Katie Williams, Christina D Orrú, Hailey Lachenauer, Bradley R Groveman, Cathryn L Haigh

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Altered energy metabolism in Fatal Familial Insomnia cerebral organoids is associated with astrogliosis and neuronal dysfunction by Simote T. Foliaki, Anna Smith, Benjamin Schwarz, Eric Bohrnsen, Catharine M. Bosio, Katie Williams, Christina D. Orrú, Hailey Lachenauer, Bradley R. Groveman, Cathryn L. Haigh

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Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc. by Simote Totauhelotu Foliaki, Victoria Lewis, Abu Mohammed Taufiqual Islam, Laura Jane Ellett, Matteo Senesi, David Isaac Finkelstein, Blaine Roberts, Victoria A Lawson, Paul Anthony Adlard, Steven John Collins

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Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species. by Simote Totauhelotu Foliaki, Victoria Lewis, David Isaac Finkelstein, Victoria Lawson, Harold Arthur Coleman, Matteo Senesi, Abu Mohammed Taufiqual Islam, Feng Chen, Shannon Sarros, Blaine Roberts, Paul Anthony Adlard, Steven John Collins

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Neuronal excitatory-to-inhibitory balance is altered in cerebral organoid models of genetic neurological diseases by Simote T. Foliaki, Benjamin Schwarz, Bradley R. Groveman, Ryan O. Walters, Natalia C. Ferreira, Christina D. Orrù, Anna Smith, Aleksandar Wood, Olivia M. Schmit, Phoebe Freitag, Jue Yuan, Wenquan Zou, Catharine M. Bosio, James A. Carroll, Cathryn L. Haigh

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