Transformation and survival in marginal zone lymphoma: a Finnish nationwide population-based study by Ilja Kalashnikov, Tomas Tanskanen, Leevi Viisanen, Nea Malila, Sirkku Jyrkkiö, Sirpa Leppä

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S227: INITIAL SAFETY DATA FROM THE PHASE 3 POLAR BEAR TRIAL IN ELDERLY OR FRAIL PATIENTS WITH DIFFUSE LARGE CELL LYMPHOMA, COMPARING R-POLA-MINI-CHP AND R-MINI-CHOP by Mats Jerkeman, Sirpa Leppä, Julian Hamfjord, Peter Brown, Sara Ekberg, Andrés José María Ferreri

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T026: Characterization of cancer-associated fibroblasts in classical Hodgkin lymphoma by Kristiina Karihtala, Suvi-Katri Leivonen, Marja-Liisa Karjalainen-Lindsberg, Arne Östman, Teijo Pellinen, Sirpa Leppä

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Serum protein profiling reveals an inflammation signature as a predictor of early breast cancer survival by Peeter Karihtala, Suvi-Katri Leivonen, Ulla Puistola, Elina Urpilainen, Anniina Jääskeläinen, Sirpa Leppä, Arja Jukkola

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Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma by Matias Autio, Suvi-Katri Leivonen, Oscar Brück, Satu Mustjoki, Judit Mészáros Jørgensen, Marja-Liisa Karjalainen-Lindsberg, Klaus Beiske, Harald Holte, Teijo Pellinen, Sirpa Leppä

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Characterization of tumor microenvironment and cell interaction patterns in testicular and diffuse large B-cell lymphomas by Matias Autio, Oscar Brück, Marjukka Pollari, Marja-Liisa Karjalainen-Lindsberg, Klaus Beiske, Judit Mészaros Jørgensen, Harald Holte, Teijo Pellinen, Suvi-Katri Leivonen, Sirpa Leppä

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Prognostic influence of macrophages in patients with diffuse large B-cell lymphoma: a correlative study from a Nordic phase II trial by Sari Riihijärvi, Idun Fiskvik, Minna Taskinen, Heli Vajavaara, Maria Tikkala, Olav Yri, Marja-Liisa Karjalainen-Lindsberg, Jan Delabie, Erlend Smeland, Harald Holte, Sirpa Leppä

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T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma by Suvi-Katri Leivonen, Marjukka Pollari, Oscar Brück, Teijo Pellinen, Matias Autio, Marja-Liisa Karjalainen-Lindsberg, Susanna Mannisto, Pirkko-Liisa Kellokumpu-Lehtinen, Olli Kallioniemi, Satu Mustjoki, Sirpa Leppä

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PD-L1+ tumor-associated macrophages and PD-1+ tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma by Marjukka Pollari, Oscar Brück, Teijo Pellinen, Pauli Vähämurto, Marja-Liisa Karjalainen-Lindsberg, Susanna Mannisto, Olli Kallioniemi, Pirkko-Liisa Kellokumpu-Lehtinen, Satu Mustjoki, Suvi-Katri Leivonen, Sirpa Leppä

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Successful change of treatment strategy in elderly patients with primary central nervous system lymphoma by de-escalating induction and introducing temozolomide maintenance: result... by Elisa J. Pulczynski, Outi Kuittinen, Martin Erlanson, Hans Hagberg, Alexander Fosså, Mikael Eriksson, Marie Nordstrøm, Bjørn Østenstad, Øystein Fluge, Sirpa Leppä, Bente Fiirgaard, Hanne Bersvendsen, Unn-Merete Fagerli

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Deltex-1 mutations predict poor survival in diffuse large B-cell lymphoma by Leo Meriranta, Annika Pasanen, Riku Louhimo, Alejandra Cervera, Amjad Alkodsi, Matias Autio, Minna Taskinen, Ville Rantanen, Marja-Liisa Karjalainen-Lindsberg, Harald Holte, Jan Delabie, Rainer Lehtonen, Sampsa Hautaniemi, Sirpa Leppä

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Characterization and clinical impact of the tumor microenvironment in post-transplant aggressive B-cell lymphomas by Suvi-Katri Leivonen, Terhi Friman, Matias Autio, Samuli Vaittinen, Andreas Wind Jensen, Francesco d’Amore, Stephen Jacques Hamilton-Dutoit, Harald Holte, Klaus Beiske, Panu E. Kovanen, Riikka Räty, Sirpa Leppä

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Proteomics uncovers molecular features for relapse risk stratification in patients with diffuse large B-cell lymphoma by Maja Ludvigsen, Amanda Jessica Campbell, Marie Beck Enemark, Trine Engelbrecht Hybel, Marja-Liisa Karjalainen-Lindsberg, Klaus Beiske, Mette Bjerre, Lars Møller Pedersen, Harald Holte, Sirpa Leppä, Judit Meszaros Jørgensen, Bent Honoré

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Prognostic impact of soluble CD163 in patients with diffuse large B-cell lymphoma by Heli Vajavaara, Frida Ekeblad, Harald Holte, Judit Jorgensen, Suvi-Katri Leivonen, Mattias Berglund, Peter Kamper, Holger J. Moller, Francesco d’Amore, Daniel Molin, Gunilla Enblad, Maja Ludvigsen, Ingrid Glimelius, Sirpa Leppa

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Elderly long-term survivors in the Nordic phase II study with first-line maintenance temozolomide for primary central nervous system lymphoma: a 10-year follow-up by Elisa Jacobsen Pulczynski, Mikkel Runason Simonsen, Outi Kuittinen, Unn-Merete Fagerli, Martin Erlanson, Øystein Fluge, Sirpa Leppä, Bjørn Østenstad, Alexander Fosså, Mikael Eriksson, Tarec El-Galaly, Hanne Kuitunen, Karin Papworth, Maria Ljungqvist, Martin B. Pedersen, Marjukka Pollari

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S222: EPCORITAMAB WITH RITUXIMAB + LENALIDOMIDE (R2) PROVIDES DURABLE RESPONSES IN PATIENTS WITH HIGH-RISK FOLLICULAR LYMPHOMA, REGARDLESS OF POD24 STATUS by Anna Sureda, Lorenzo Falchi, Sirpa Leppa, Joost Vermaat, Harald Holte, Martin Hutchings, Pieternella Lugtenburg, Sven de Vos, Pau Abrisqueta, Marcel Nijland, Reid W. Merryman, Jacob Haaber Christensen, Bjorn Wahlin, Kim Linton, Liwei Wang, Aqeel Abbas, Ali Rana, Syed Quadri, David Belada

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Dexamethasone is associated with reduced frequency and intensity of cytokine release syndrome compared with alternative corticosteroid regimens as premedication for glofitamab in p... by Lorenzo Falchi, Martin Hutchings, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquin Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua D. Brody, Sirpa Leppä, Aurelien Berthier, Martine Kallemeijn, James Relf, Fabiola Bene Tchaleu, Linda Lundberg, Emmanuel Bachy.

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P1129: GLOFITAMAB MONOTHERAPY IN PATIENTS WITH RELAPSED/REFRACTORY (R/R) LARGE B-CELL LYMPHOMA (LBCL): EXTENDED FOLLOW-UP AND LANDMARK ANALYSES FROM A PIVOTAL PHASE II STUDY by Martin Hutchings, Carmelo Carlo-Stella, Franck Morschhauser, Michael Dickinson, Emmanuel Bachy, Guillaume Cartron, Cyrus Khan, Monica Tani, Joaquín Martinez-Lopez, Nancy L. Bartlett, Antonio Salar, Joshua Brody, Sirpa Leppa, Pauline Baumlin, Linda Lundberg, James Relf, Yuying Xie, Alessia Bottos, Kathryn Humphrey, Lorenzo Falchi

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Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours by Surbhi Mishra, Mysore Vishakantegowda Tejesvi, Jenni Hekkala, Jenni Turunen, Niyati Kandikanti, Anna Kaisanlahti, Marko Suokas, Sirpa Leppä, Pia Vihinen, Hanne Kuitunen, Kaisa Sunela, Jussi Koivunen, Arja Jukkola, Ilja Kalashnikov, Päivi Auvinen, Okko-Sakari Kääriäinen, T. Peñate Medina, O. Peñate Medina, Juha Saarnio, Sanna Meriläinen, Tero Rautio, Raila Aro, Reetta Häivälä, Juho Suojanen, Mikael Laine, Pande Putu Erawijattari, Leo Lahti, Peeter Karihtala, Terhi S. Ruuska, Justus Reunanen

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The EHA Research Roadmap: Malignant Lymphoid Diseases by Martin Dreyling, Marc André, Nicola Gökbuget, Hervé Tilly, Mats Jerkeman, John Gribben, Andrés Ferreri, Pierre Morel, Stephan Stilgenbauer, Christopher Fox, José Maria Ribera, Sonja Zweegman, Igor Aurer, Csaba Bödör, Birgit Burkhardt, Christian Buske, Maria Dollores Caballero, Elias Campo, Bjoern Chapuy, Andrew Davies, Laurence de Leval, Jeanette Doorduijn, Massimo Federico, Philippe Gaulard, Francesca Gay, Paolo Ghia, Kirsten Grønbæk, Hartmut Goldschmidt, Marie-Jose Kersten, Barbara Kiesewetter, Judith Landman-Parker, Steven Le Gouill, Georg Lenz, Sirpa Leppä, Armando Lopez-Guillermo, Elizabeth Macintyre, Maria Victoria Mateos Mantega, Philippe Moreau, Carol Moreno, Bertrand Nadel, Jessica Okosun, Roger Owen, Sarka Pospisilova, Christiane Pott, Tadeusz Robak, Michelle Spina, Kostas Stamatopoulos, Jan Stary, Karin Tarte, Allessandra Tedeschi, Catherine Thieblemont, Ralf Ulrich Trappe, Lorenz H. Trümper, Gilles Salles

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