FKBP12 is a high affinity, reversible activator of RyR2, and FKBP12.6 antagonises its actions by Sitsapesan, R, Pitt, SJ, Venturi, E, Galfre, E, O'Neill, S, Sitsapesan, M

Modelling the ATP binding site of RyR2 to rationalise ligand-induced gating behaviour by Lindsay, C, Sitsapesan, M, Chan, WM, Venturi, E, Welch, W, Musgaard, M, Sitsapesan, RM

Promiscuous attraction of ligands within the ATP binding site of RyR2 promotes diverse gating behaviour by Lindsay, C, Sitsapesan, M, Chen, W, Venturi, E, Welch, W, Musgaard, M, Sitsapesan, R

FKBP12 activates the cardiac ryanodine receptor Ca2+-release channel and is antagonised by FKBP12.6. by Galfré, E, Pitt, S, Venturi, E, Sitsapesan, M, Zaccai, N, Tsaneva-Atanasova, K, O'Neill, S, Sitsapesan, R

TPC2 is a novel NAADP-sensitive Ca2+ release channel, operating as a dual sensor of luminal pH and Ca2+. by Pitt, S, Funnell, T, Sitsapesan, M, Venturi, E, Rietdorf, K, Ruas, M, Ganesan, A, Gosain, R, Churchill, G, Zhu, M, Parrington, J, Galione, A, Sitsapesan, R