Genetic association analysis of RHOB and TXNDC3 in osteoarthritis. by Loughlin, J, Meulenbelt, I, Min, J, Mustafa, Z, Sinsheimer, J, Carr, A, Slagboom, P

Interleukin-1 region meta-analysis with osteoarthritis phenotypes. by Moxley, G, Meulenbelt, I, Chapman, K, van Diujn, C, Slagboom, P, Neale, M, Smith, A, Carr, A, Loughlin, J

Meta-analyses of genes modulating intracellular T3 bio-availability reveal a possible role for the DIO3 gene in osteoarthritis susceptibility. by Meulenbelt, I, Bos, S, Chapman, K, van der Breggen, R, Houwing-Duistermaat, J, Kremer, D, Kloppenburg, M, Carr, A, Tsezou, A, González, A, Loughlin, J, Slagboom, P

META-ANALYSIS IDENTIFIES NOVEL GENES INFLUENCING LEVELS OF THE POTENTIAL OA BIOMARKERS SCOMP AND UCTX2 by Ramos, Y, van Meurs, J, Valdes, A, Metrustry, S, Hart, D, Arden, N, Kloppenburg, M, Lafeber, F, van Spil, E, Karsdal, M, Bay-Jensen, A, Spector, T, Uitterlinden, A, Slagboom, P, Meulenbelt, I

Replication of LDL GWAs hits in PROSPER/PHASE as validation for future (pharmaco)genetic analyses by Stott David J, Caslake Muriel, Sattar Naveed, Ford Ian, Postmus Iris, de Craen Anton JM, Trompet Stella, Buckley Brendan M, Sacks Frank, Devlin James J, Slagboom P, Westendorp Rudi GJ, Jukema J

Get full text

A whole genome association study of neuroticism using DNA pooling. by Shifman, S, Bhomra, A, Smiley, S, Wray, N, James, MR, Martin, N, Hettema, J, An, S, Neale, M, van den Oord, E, Kendler, K, Chen, X, Boomsma, D, Middeldorp, C, Hottenga, J, Slagboom, P, Flint, J

Effects of a Web-Based Intervention on Physical Activity and Metabolism in Older Adults: Randomized Controlled Trial by Wijsman, Carolien A, Westendorp, Rudi GJ, Verhagen, Evert ALM, Catt, Michael, Slagboom, P Eline, de Craen, Anton JM, Broekhuizen, Karen, van Mechelen, Willem, van Heemst, Diana, van der Ouderaa, Frans, Mooijaart, Simon P

Get full text

Incident venous thromboembolic events in the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) by Ford Ian, Sattar Naveed, de Craen Anton JM, Jukema J Wouter, Slagboom P Eline, Frölich Marijke, Tobias Edward S, Rumley Ann, Brown E Ann, Robertson Michele, Freeman Dilys J, Gaw Allan, Greer Ian A, Lowe Gordon DO, Stott David J

Get full text

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts by van Leeuwen, N, Nijpels, G, Becker, M, Deshmukh, H, Zhou, K, Stricker, B, Uitterlinden, A, Hofman, A, van 't Riet, E, Palmer, C, Guigas, B, Slagboom, P, Durrington, P, Calle, R, Neil, A, Hitman, G, Livingstone, S, Colhoun, H, Holman, R, McCarthy, M, Dekker, J, 't Hart, L, Pearson, E

A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts. by van Leeuwen, N, Nijpels, G, Becker, M, Deshmukh, H, Zhou, K, Stricker, B, Uitterlinden, A, Hofman, A, van 't Riet, E, Palmer, C, Guigas, B, Slagboom, P, Durrington, P, Calle, R, Neil, A, Hitman, G, Livingstone, S, Colhoun, H, Holman, R, McCarthy, M, Dekker, J, 't Hart, L, Pearson, E

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-II with genome wide significance. by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Meta-analysis identifies loci affecting levels of the potential osteoarthritis biomarkers sCOMP and uCTX-ii with genome wide significance by Ramos, Y, Metrustry, S, Arden, N, Bay-Jensen, A, Beekman, M, de Craen, A, Cupples, L, Esko, T, Evangelou, E, Felson, D, Hart, D, Ioannidis, J, Karsdal, M, Kloppenburg, M, Lafeber, F, Metspalu, A, Panoutsopoulou, K, Slagboom, P, Spector, T, van Spil, E, Uitterlinden, A, Zhu, Y, Valdes, A, van Meurs, J, Meulenbelt, I

Genetic association analysis of LARS2 with type 2 diabetes. by Reiling, E, Jafar-Mohammadi, B, van 't Riet, E, Weedon, M, van Vliet-Ostaptchouk, J, Hansen, T, Saxena, R, van Haeften, T, Arp, P, Das, S, Nijpels, G, Groenewoud, M, van Hove, E, Uitterlinden, A, Smit, J, Morris, A, Doney, A, Palmer, C, Guiducci, C, Hattersley, A, Frayling, T, Pedersen, O, Slagboom, P, Altshuler, D, Groop, L

Autosomal genetic variation is associated with DNA methylation in regions variably escaping X-chromosome inactivation by Luijk, R, Wu, H, Ward-Caviness, C, Hannon, E, Carnero-Montoro, E, Min, J, Mandaviya, P, Müller-Nurasyid, M, Mei, H, Van Der Maarel, S, BIOS Consortium, Relton, C, Mill, J, Waldenberger, M, Bell, J, Jansen, R, Zhernakova, A, Franke, L, 'T Hoen, P, Boomsma, D, Van Duijn, C, Van Greevenbroek, M, Veldink, J, Wijmenga, C, Van Meurs, J, Daxinger, L, Slagboom, P, Van Zwet, E, Heijmans, B

Metabolite ratios as potential biomarkers for type 2 diabetes: a DIRECT study. by Molnos, S, Wahl, S, Haid, M, Eekhoff, E, Pool, R, Floegel, A, Deelen, J, Much, D, Prehn, C, Breier, M, Draisma, H, van Leeuwen, N, Simonis-Bik, A, Jonsson, A, Willemsen, G, Bernigau, W, Wang-Sattler, R, Suhre, K, Peters, A, Thorand, B, Herder, C, Rathmann, W, Roden, M, Gieger, C, Kramer, M, van Heemst, D, Pedersen, H, Gudmundsdottir, V, Schulze, M, Pischon, T, de Geus, E, Boeing, H, Boomsma, D, Ziegler, A, Slagboom, P, Hummel, S, Beekman, M, Grallert, H, Brunak, S, McCarthy, M, Gupta, R, Pearson, E, Adamski, J, 't Hart, L

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study. by Zeggini, E, Panoutsopoulou, K, Southam, L, Rayner, N, Day-Williams, A, Lopes, M, Boraska, V, Esko, T, Evangelou, E, Hoffman, A, Houwing-Duistermaat, J, Ingvarsson, T, Jonsdottir, I, Jonnson, H, Kerkhof, H, Kloppenburg, M, Bos, S, Mangino, M, Metrustry, S, Slagboom, P, Thorleifsson, G, Raine, E, Ratnayake, M, Ricketts, M, Beazley, C, Blackburn, H, Bumpstead, S, Elliott, K, Hunt, SE, Potter, S, Shin, S, Yadav, V, Zhai, G, Sherburn, K, Dixon, K, Arden, E, Aslam, N, Battley, P, Carluke, I, Doherty, S, Gordon, A, Joseph, J, Keen, R, Koller, N, Mitchell, S, O'Neill, F, Paling, E, Reed, MR, Rivadeneira, F, Swift, D, Walker, K, Watkins, B, Wheeler, M, Birrell, F, Ioannidis, J, Meulenbelt, I, Metspalu, A, Rai, A, Salter, D, Stefansson, K, Stykarsdottir, U, Uitterlinden, A, van Meurs, J, Chapman, K, Deloukas, P, Ollier, W, Wallis, G, Arden, N, Carr, A, Doherty, M, McCaskie, A, Willkinson, J, Ralston, S, Valdes, A, Spector, T, Loughlin, J

Association of maternal prenatal smoking GFI1-locus and cardio-metabolic phenotypes in 18,212 adults by Chambers, John Campbell, Parmar, Priyanka, Lowry, Estelle, Cugliari, Giovanni, Suderman, Matthew, Wilson, Rory, Karhunen, Ville, Andrew, Toby, Wiklund, Petri, Wielscher, Matthias, Guarrera, Simonetta, Teumer, Alexander, Lehne, Benjamin, Milani, Lili, de Klein, Niek, Mishra, Pashupati P., Melton, Phillip E., Mandaviya, Pooja R., Kasela, Silva, Nano, Jana, Zhang, Weihua, Zhang, Yan, Mori, Trevor A., Bonnefond, Amelie, Uitterlinden, Andre G., Peters, Annette, Schöttker, Ben, Gieger, Christian, Anderson, Denise, Boomsma, Dorret I., Grabe, Hans J., Panico, Salvatore, Veldink, Jan H., van Meurs, Joyce B.J., van den Berg, Leonard, Heijmans, Bastiaan T., Muka, Taulant, Kooner, Jaspal S., Fischer, Krista, Waldenberger, Melanie, Beilin, Lawrence J., Franke, Lude, Loh, Marie, van Greevenbroek, Marleen M.J., Nauck, Matthias, Kähönen, Mika, Hurme, Mikko A., Raitakari, Olli T., Franco, Oscar H., Slagboom, P.Eline, van der Harst, Pim, Kunze, Sonja, Felix, Stephan B., Zhang, Tao, Chen, Wei, Froguel, Philippe, Huang, Rae-Chi, Lehtimäki, Terho, Rathmann, Wolfgang, Relton, Caroline L., Matullo, Giuseppe, Brenner, Hermann, Verweij, Niek, Li, Shengxu, Järvelin, Marjo-Riitta, Sebert, Sylvain

Get full text
Get full text

Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study. by de Vries, P, Sabater-Lleal, M, Chasman, D, Trompet, S, Ahluwalia, T, Teumer, A, Kleber, M, Chen, M, Wang, J, Attia, J, Marioni, R, Steri, M, Weng, L, Pool, R, Grossmann, V, Brody, J, Venturini, C, Tanaka, T, Rose, L, Oldmeadow, C, Mazur, J, Basu, S, Frånberg, M, Yang, Q, Ligthart, S, Hottenga, J, Rumley, A, Mulas, A, de Craen, A, Grotevendt, A, Taylor, K, Delgado, G, Kifley, A, Lopez, L, Berentzen, T, Mangino, M, Bandinelli, S, Morrison, A, Hamsten, A, Tofler, G, de Maat, M, Draisma, H, Lowe, G, Zoledziewska, M, Sattar, N, Lackner, K, Völker, U, McKnight, B, Huang, J, Holliday, E, McEvoy, M, Starr, J, Hysi, P, Hernandez, D, Guan, W, Rivadeneira, F, McArdle, W, Slagboom, P, Zeller, T, Psaty, B, Uitterlinden, A, de Geus, E, Stott, D, Binder, H, Hofman, A, Franco, O, Rotter, J, Ferrucci, L, Spector, T, Deary, I, März, W, Greinacher, A, Wild, P, Cucca, F, Boomsma, D, Watkins, H, Tang, W, Ridker, P, Jukema, J, Scott, R, Mitchell, P, Hansen, T, O'Donnell, C, Smith, N, Strachan, D, Dehghan, A

No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: results from meta-analyses of 80,607 subjects by Baumert, J, Huang, J, McKnight, B, Sabater-Lleal, M, Steri, M, Chu, A, Trompet, S, Lopez, L, Fornage, M, Teumer, A, Tang, W, Rudnicka, A, Mälarstig, A, Hottenga, J, Kavousi, M, Lahti, J, Tanaka, T, Hayward, C, Huffman, J, Morange, P, Rose, L, Basu, S, Rumley, A, Stott, D, Buckley, B, De Craen, A, Sanna, S, Masala, M, Biffar, R, Homuth, G, Silveira, A, Sennblad, B, Goel, A, Watkins, H, Müller-Nurasyid, M, Rückerl, R, Taylor, K, Chen, M, De Geus, E, Hofman, A, Witteman, J, Maat, D, Palotie, A, Davies, G, Siscovick, D, Kolcic, I, Wild, S, Song, J, McArdle, W, Ford, I, Sattar, N, Schlessinger, D, Grotevendt, A, Franzosi, MG, Illig, T, Waldenberger, M, Lumley, T, Tofler, G, Willemsen, G, Uitterlinden, A, Rivadeneira, F, Räikkönen, K, Chasman, D, Folsom, A, Lowe, G, Westendorp, R, Slagboom, P, Cucca, F, Wallaschofski, H, Strawbridge, R, Seedorf, U, Koenig, W, Bis, J, Mukamal, K, Van Dongen, J, Widen, E, Franco, O, Starr, J, Liu, K, Ferrucci, L, Polasek, O, Wilson, J, Oudot-Mellakh, T, Campbell, H, Navarro, P, Bandinelli, S, Eriksson, J, Boomsma, D, Dehghan, A, Clarke, R, Hamsten, A, Boerwinkle, E, Jukema, J, Naitza, S, Ridker, P, Völzke, H, Deary, I, Reiner, A, Trégouët, D, O'Donnell, C, Strachan, D, Peters, A, Smith, N

Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins by Postmus, I, Trompet, S, Deshmukh, H, Barnes, MR, Li, X, Warren, H, Chasman, D, Zhou, K, Arsenault, B, Donnelly, L, Wiggins, K, Avery, C, Griffin, P, Feng, Q, Taylor, K, Li, G, Evans, D, Smith, A, De Keyser, C, Johnson, A, De Craen, A, Stott, D, Buckley, B, Ford, I, Westendorp, R, Slagboom, P, Sattar, N, Munroe, P, Sever, P, Poulter, N, Stanton, A, Shields, D, O'Brien, E, Shaw-Hawkins, S, Chen, Y, Nickerson, D, Smith, J, Dubé, M, Boekholdt, S, Hovingh, G, Kastelein, J, McKeigue, P, Betteridge, J, Neil, A, Durrington, P, Doney, A, Carr, F, Morris, A, McCarthy, M, Groop, L, Ahlqvist, E, Bis, J, Rice, K, Smith, N, Lumley, T, Whitsel, E, Stürmer, T, Boerwinkle, E, Ngwa, J, O'Donnell, C, Vasan, R, Wei, W, Wilke, R, Liu, C, Sun, F, Guo, X, Heckbert, SR, Post, W, Sotoodehnia, N, Arnold, A, Stafford, J, Ding, J, Herrington, D, Kritchevsky, S, Eiriksdottir, G, Launer, L, Harris, T, Chu, A, Giulianini, F, Macfadyen, J, Barratt, B, Nyberg, F, Stricker, B, Uitterlinden, A, Hofman, A, Rivadeneira, F, Emilsson, V, Franco, O, Ridker, P, Gudnason, V, Liu, Y, Denny, J, Ballantyne, C, Rotter, J, Adrienne Cupples, L, Psaty, B, Palmer, C, Tardif, J, Colhoun, H, Hitman, G, Krauss, R, Wouter Jukema, J, Caulfield, M, Wellcome Trust Case Control Consortium