1371 Novel orally active and high tissue penetrant small molecules targeting surface and intracellular PD-L1 signals for cancer immunotherapy by Nattiya Hirankarn, Trairak Pisitkun, Nonthaneth Nalinratana, Niphat Jirapongwattana, Udomsak Udomnilobol, Songkiat Songthammanuphap, Eakkaphon Rattanangkool, Nopparat Thavornsin, Sirikan Deesiri, Jakkrit Srisa, Jakapun Soponpong, Supanan Ampawa, Chayan Charoenpakdee, Wilasinee Dunkoksung, Tanachote Ruengsatra, Supranee Buranapraditkun, Tirayut Vilaivan, Thomayant Prueksaritanont