1367 A rational approach to selecting CD3-binding antibodies for T-cell engager development by Kate Gibson, Lauren Chong, Tim Jacobs, Patrick Farber, Antonios Samiotakis, Harveer Dhupar, Allison Goodman, Cindy-Lee Crichlow, Melissa Cid, Ping Xiang, Ahn Lee, Irene Yu, Gabrielle Conaghan, Nathalie Blamey, Vivian Li, Valentine de Puyraimond, Patrick Rowe, Stephanie K Masterman, Raffi Tonikian, Bryan C Barnhart, Juntao (Matt) Mai, Philippe Pouliot, Kate Caldwell, Lauren Clifford, Janice Reimer, Karine Herve, John Marwick, Lena M Bolten, Tova Pinsky, Gesa Volkers, Girija Bodhankar, Caitlyn De Jong, Sophie Cullen, Stefan Hannie, Rhys Chappell, Emma Lathouwers, Kirstin Brown, Mark Fogg, Aaron Yamniuk