Transcription-dependent DNA double-strand breaks and human disease per Cristini, A, Gromak, N, Sordet, O

RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation per Cristini, A, Tellier, M, Constantinescu, F, Accalai, C, Albulescu, LO, Heiringhoff, R, Bery, N, Sordet, O, Murphy, S, Gromak, N

Dual processing of R-loops and topoisomerase I induces transcription-dependent DNA double-strand breaks per Cristini, A, Ricci, G, Britton, S, Salimbeni, S, Huang, S, Marinello, J, Calsou, P, Pommier, Y, Favre, G, Capranico, G, Gromak, N, Sordet, O