Finer linkage mapping of primary hip osteoarthritis susceptibility on chromosome 11q in a cohort of affected female sibling pairs. by Chapman, K, Mustafa, Z, Dowling, B, Southam, L, Carr, A, Loughlin, J

Extreme context specificity in differential allelic expression. by Wilkins, J, Southam, L, Price, A, Mustafa, Z, Carr, A, Loughlin, J

Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants? by Southam, L, Soranzo, N, Montgomery, S, Frayling, T, McCarthy, M, Barroso, I, Zeggini, E

Differential allelic expression of protein tyrosine phosphatase NonReceptor 22 in rheumatoid arthritis patients by Harrison, P, Southam, L, Pointon, J, Chapman, K, Locklin, R, Sabokbar, A, Wordsworth, B

Evidence of cis-acting regulatory variation in PTPN22 in patients with rheumatoid arthritis. by Harrison, P, Southam, L, Chapman, K, Locklin, R, Sabokbar, A, Wordsworth, B, Pointon, J

Microsatellite association mapping of a primary osteoarthritis susceptibility locus on chromosome 6p12.3-q13. by Southam, L, Dowling, B, Ferreira, A, Marcelline, L, Mustafa, Z, Chapman, K, Bentham, G, Carr, A, Loughlin, J

Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism. by Egli, R, Southam, L, Wilkins, J, Lorenzen, I, Pombo-Suarez, M, Gonzalez, A, Carr, A, Chapman, K, Loughlin, J

An SNP in the 5'-UTR of GDF5 is associated with osteoarthritis susceptibility in Europeans and with in vivo differences in allelic expression in articular cartilage. by Southam, L, Rodriguez-Lopez, J, Wilkins, J, Pombo-Suarez, M, Snelling, S, Gomez-Reino, J, Chapman, K, Gonzalez, A, Loughlin, J

Comparison of fluorescent single-strand conformation polymorphism analysis and denaturing high-performance liquid chromatography for detection of EXT1 and EXT2 mutations in heredit... by Dobson-Stone, C, Cox, R, Lonie, L, Southam, L, Fraser, M, Wise, C, Bernier, F, Hodgson, S, Porter, D, Simpson, A, Monaco, A

Genetic drivers of heterogeneity in type 2 diabetes pathophysiology by Suzuki, K, Hatzikotoulas, K, Southam, L, Bragg, F, Lin, K, Chen, Z, Millwood, I, Walters, R, Lindgren, C, Sun, M, McCarthy, M, Mahajan, A

Angiotensin-1-converting enzyme (ACE) plasma concentration is influenced by multiple ACE-linked quantitative trait nucleotides. by Cox, R, Bouzekri, N, Martin, S, Southam, L, Hugill, A, Golamaully, M, Cooper, R, Adeyemo, A, Soubrier, F, Ward, R, Lathrop, G, Matsuda, F, Farrall, M

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution by Justice, A, Karaderi, T, Highland, H, Mahajan, A, Gan, W, Karpe, F, Kitajima, H, McCarthy, M, Morris, A, Neville, C, Owen, K, Robertson, N, Southam, L, Lindgren, C

A genome-wide association study of Dupuytren's disease reveals 17 additional variants implicated in fibrosis by Ng, M, Thakkar, D, Southam, L, Werker, P, Ophoff, R, Becker, K, Nothnagel, M, Franke, A, Nurnberg, P, Espirito-Santo, A, Izadi, D, Hennies, H, Nanchahal, J, Zeggini, E, Furniss, D

Identification and characterization of novel parathyroid-specific transcription factor Glial Cells Missing Homolog B (GCMB) mutations in eight families with autosomal recessive hyp... by Bowl, MR, Mirczuk, S, Grigorieva, I, Piret, SE, Cranston, T, Southam, L, Allgrove, J, Bahl, S, Brain, C, Loughlin, J, Mughal, Z, Ryan, F, Shaw, N, Thakker, Y, Tiosano, D, Nesbit, M, Thakker, R

Rare and low-frequency coding variants alter human adult height by Marouli, E, Graff, M, Medina-Gomez, M, Karaderi, T, Mahajan, A, Gan, W, Kitajima, H, Karpe, F, Morris, A, Neville, M, Owen, K, Robertson, N, Southam, L, McCarthy, M, Lindgren, C, al., E

Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data by Zeggini, E, Tachmazidou, I, Hatzikotoulas, K, Southam, L, Gordillo, J, Wilkinson, J, Bhatnagar, S, Hoffman, J, Buchan, N, Suveges, D, Armstrong, L, Smith, G, Gaunt, T, Scott, R, McCarthy, L, Carr, AJ, arcOGEN Consortium

Whole genome sequencing coupled to imputation discovers genetic signals for anthropometric traits by Tachmazidou, I, Süveges, D, Min, J, Rayner, N, Southam, L, McCarthy, M, Lindgren, C, Morris, A, SpiroMeta consortium, GoT2D consortium, arcOGEN consortium, Understanding Society Scientific Group, UK10K consortium

The effect of genome-wide association scan quality control on imputation outcome for common variants. by Southam, L, Panoutsopoulou, K, Rayner, N, Chapman, K, Durrant, C, Ferreira, T, Arden, N, Carr, A, Deloukas, P, Doherty, M, Loughlin, J, McCaskie, A, Ollier, W, Ralston, S, Spector, T, Valdes, A, Wallis, G, Wilkinson, J, Marchini, J, Zeggini, E

The effect of genome-wide association scan quality control on imputation outcome for common variants. by Southam, L, Panoutsopoulou, K, Rayner, N, Chapman, K, Durrant, C, Ferreira, T, Arden, N, Carr, A, Deloukas, P, Doherty, M, Loughlin, J, McCaskie, A, Ollier, W, Ralston, S, Spector, T, Valdes, A, Wallis, G, Wilkinson, J, arcOGEN consortium, Marchini, J, Zeggini, E

No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls. by Hudson, G, Panoutsopoulou, K, Wilson, I, Southam, L, Rayner, N, Arden, N, Birrell, F, Carluke, I, Carr, A, Chapman, K, Deloukas, P, Doherty, M, McCaskie, A, Ollier, W, Ralston, S, Reed, MR, Spector, T, Valdes, A, Wallis, G, Wilkinson, J, Zeggini, E, Samuels, D, Loughlin, J, Chinnery, P