A heritability-based comparison of methods used to cluster 16S rRNA gene sequences into operational taxonomic units von Jackson, MA, Bell, JT, Spector, TD, Steves, CJ

Effect of heeled shoes on joint symptoms and knee osteoarthritis in older adults: a 5-year follow-up study von Perry, TA, Dando, C, Spector, TD, Hart, DJ, Bowen, C, Arden, N

Specific body mass index trajectories were related to musculoskeletal pain and mortality: 19-year follow-up cohort von Radojčić, MR, Perera, RS, Chen, L, Spector, TD, Hart, DJ, Ferreira, ML, Arden, NK

Effects of body weight and fat mass on back pain – direct mechanical or indirect through inflammatory and metabolic parameters? von Perera, RS, Chen, L, Hart, DJ, Spector, TD, Arden, NK, Ferreira, ML, Radojčić, MR

No evidence of leptin mediating the effect of body mass index on hand pain and its duration in the Chingford 1000 Women Study: original research supplementing the study by Gløersen... von Perera, RS, Gulati, M, Shah, K, Hart, DJ, Spector, TD, Arden, NK, Radojčić, MR

Socioeconomic Status and the Gut Microbiome: A TwinsUK Cohort Study von Bowyer, RCE, Jackson, MA, Le Roy, CI, Ni Lochlainn, M, Spector, TD, Dowd, JB, Steves, CJ

Interaction between race and sex in measures of hip morphology: a population-based comparative study von Edwards, K, Leyland, KM, Arden, CP, Spector, TD, Nelson, AE, Jordan, JM, Nevitt, M, Hunter, DJ, Arden, NK

Association of lumbar spine radiographic changes with severity of back pain-related disability among middle-aged, community-dwelling women von Chen, L, Perera, RS, Radojčić, MR, Beckenkamp, PR, Ferreira, PH, Hart, DJ, Spector, TD, Arden, NK, Ferreira, ML

The incidence and characteristics of accelerated knee osteoarthritis among women: the Chingford cohort von Driban, JB, Bannuru, RR, Eaton, CB, Spector, TD, Hart, DJ, McAlindon, TE, Lu, B, Lo, GH, Arden, NK

Differences between race and sex in measures of hip morphology: a population-based comparative study von Edwards, K, Leyland, KM, Sanchez-Santos, MT, Arden, CP, Spector, TD, Nelson, AE, Jordan, JM, Nevitt, M, Hunter, DJ, Arden, NK

Hippurate as a metabolomic marker of gut microbiome diversity: Modulation by diet and relationship to metabolic syndrome von Pallister, T, Jackson, MA, Martin, TC, Zierer, J, Jennings, A, Mohney, RP, Macgregor, A, Steves, CJ, Cassidy, A, Spector, TD, Menni, C

Distinct clinical symptom patterns in patients hospitalised with COVID-19 in an analysis of 59,011 patients in the ISARIC-4C study von Millar, JE, Neyton, L, Seth, S, Dunning, J, Merson, L, Murthy, S, Russell, CD, Keating, S, Swets, M, Sudre, CH, Spector, TD, Ourselin, S, Steves, CJ, Wolf, J, Docherty, AB, Harrison, EM, Openshaw, PJM, Semple, MG, Baillie, JK

Novel genetic variants for cartilage thickness and hip osteoarthritis von Castaño-Betancourt, MC, Evans, DS, Ramos, YF, Boer, CG, Metrustry, S, Liu, Y, Hollander, W, van Rooij, J, Kraus, VB, Yau, MS, Mitchell, BD, Muir, K, Hofman, A, Doherty, M, Doherty, S, Zhang, W, Kraaij, R, Rivadeneira, F, Barrett-Connor, E, Maciewicz, RA, Arden, N, Nelissen, RG, Kloppenburg, M, Jordan, JM, Nevitt, MC, Slagboom, EP, Hart, DJ, Lafeber, F, Styrkarsdottir, U, Zeggini, E, Evangelou, E, Spector, TD, Uitterlinden, AG, Lane, NE, Meulenbelt, I, Valdes, AM, van Meurs, JB

Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways von Duffy, DL, Zhu, G, Li, X, Sanna, M, Iles, MM, Jacobs, LC, Evans, DM, Yazar, S, Beesley, J, Law, MH, Kraft, P, Visconti, A, Taylor, JC, Liu, F, Wright, MJ, Henders, AK, Bowdler, L, Glass, D, Ikram, MA, Uitterlinden, AG, Madden, PA, Heath, AC, Nelson, EC, Green, AC, Chanock, S, Barrett, JH, Brown, MA, Hayward, NK, Macgregor, S, Sturm, RA, Hewitt, AW, Kayser, M, Hunter, DJ, Newton Bishop, JA, Spector, TD, Montgomery, GW, Mackey, DA, Smith, GD, Nijsten, TE, Bishop, DT, Bataille, V, Falchi, M, Han, J, Martin, NG

Genome-wide association study in almost 195,000 individuals identifies 50 previously unidentified genetic loci for eye color von Simcoe, M, Valdes, A, Liu, F, Furlotte, NA, Evans, DM, Hemani, G, Ring, SM, Smith, GD, Duffy, DL, Zhu, G, Gordon, SD, Medland, SE, Vuckovic, D, Girotto, G, Sala, C, Catamo, E, Concas, MP, Brumat, M, Gasparini, P, Toniolo, D, Cocca, M, Robino, A, Yazar, S, Hewitt, A, Wu, W, Kraft, P, Hammond, CJ, Shi, Y, Chen, Y, Zeng, C, Klaver, CCW, Uitterlinden, AG, Ikram, MA, Hamer, MA, van Duijn, CM, Nijsten, T, Han, J, Mackey, DA, Martin, NG, Cheng, C-Y, 23andMe Research Team, International Visible Trait Genetics Consortium, Hinds, DA, Spector, TD, Kayser, M, Hysi, PG

Meta-analysis of epigenome-wide association studies of cognitive abilities von Marioni, RE, McRae, AF, Bressler, J, Colicino, E, Hannon, E, Li, S, Prada, D, Smith, JA, Trevisi, L, Tsai, P-C, Vojinovic, D, Simino, J, Levy, D, Liu, C, Mendelson, M, Satizabal, CL, Yang, Q, Jhun, MA, Kardia, SLR, Zhao, W, Bandinelli, S, Ferrucci, L, Hernandez, DG, Singleton, AB, Harris, SE, Starr, JM, Kiel, DP, McLean, RR, Just, AC, Schwartz, J, Spiro, A, Vokonas, P, Amin, N, Ikram, MA, Uitterlinden, AG, Van Meurs, JBJ, Spector, TD, Steves, C, Baccarelli, AA, Bell, JT, Van Duijn, CM, Fornage, M, Hsu, Y-H, Mill, J, Mosley, TH, Seshadri, S, Deary, IJ

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria von Day, F, Karaderi, T, Jones, MR, Meun, C, He, C, Drong, A, Kraft, P, Lin, N, Huang, H, Broer, L, Magi, R, Saxena, R, Laisk, T, Urbanek, M, Hayes, MG, Thorleifsson, G, Fernandez-Tajes, J, Mahajan, A, Mullin, BH, Stuckey, BGA, Spector, TD, Wilson, SG, Goodarzi, MO, Davis, L, Obermayer-Pietsch, B, Uitterlinden, AG, Anttila, V, Neale, BM, Jarvelin, M-R, Fauser, B, Kowalska, I, Visser, JA, Andersen, M, Ong, K, Stener-Victorin, E, Ehrmann, D, Legro, RS, Salumets, A, McCarthy, MI, Morin-Papunen, L, Thorsteinsdottir, U, Stefansson, K, 23Andme Research Team, Styrkarsdottir, U, Perry, JRB, Dunaif, A, Laven, J, Franks, S, Lindgren, CM, Welt, CK

Genome-wide association study of offspring birth weight in 86,577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics. von Beaumont, RN, Warrington, NM, Cavadino, A, Tyrrell, J, Nodzenski, M, Horikoshi, M, Geller, F, Myhre, R, Richmond, RC, Paternoster, L, Bradfield, JP, Kreiner-Møller, E, Huikari, V, Metrustry, S, Lunetta, KL, Painter, JN, Hottenga, J-J, Allard, C, Barton, SJ, Espinosa, A, Marsh, JA, Potter, C, Zhang, G, Ang, W, Berry, DJ, Bouchard, L, Das, S, Hakonarson, H, Heikkinen, J, Helgeland, Ø, Hocher, B, Hofman, A, Inskip, HM, Jones, SE, Kogevinas, M, Lind, PA, Marullo, L, Medland, SE, Murray, A, Murray, JC, Njølstad, PR, Nohr, EA, Reichetzeder, C, Ring, SM, Ruth, KS, Santa-Marina, L, Scholtens, DM, Sebert, S, Sengpiel, V, Tuke, MA, Vaudel, M, Weedon, MN, Willemsen, G, Wood, AR, Yaghootkar, H, Muglia, LJ, Bartels, M, Relton, CL, Pennell, CE, Chatzi, L, Estivill, X, Holloway, JW, Boomsma, DI, Montgomery, GW, Murabito, JM, Spector, TD, Power, C, Järvelin, M-R, Bisgaard, H, Grant, SF, Sørensen, TI, Jaddoe, VW, Jacobsson, B, Melbye, M, McCarthy, MI, Hattersley, AT, Hayes, MG, Frayling, TM, Hivert, M-F, Felix, JF, Hyppönen, E, Lowe, WL, Evans, DM, Lawlor, DA, Feenstra, B, Freathy, RM

Exome-derived adiponectin-associated variants implicate obesity and lipid biology von Spracklen, CN, Karaderi, T, Yaghootkar, H, Schurmann, C, Fine, RS, Kutalik, Z, Preuss, MH, Lu, Y, Wittemans, LBL, Adair, LS, Allison, M, Amin, N, Auer, PL, Bartz, TM, Blüher, M, Boehnke, M, Borja, JB, Bork-Jensen, J, Broer, L, Chasman, DI, Chen, Y-DI, Chirstofidou, P, Demirkan, A, Van Duijn, CM, Feitosa, MF, Garcia, ME, Graff, M, Grallert, H, Grarup, N, Guo, X, Haesser, J, Hansen, T, Harris, TB, Highland, HM, Hong, J, Ikram, MA, Ingelsson, E, Jackson, R, Jousilahti, P, Kähönen, M, Kizer, JR, Kovacs, P, Kriebel, J, Laakso, M, Lange, LA, Lehtimäki, T, Li, J, Li-Gao, R, Lind, L, Luan, J, Lyytikäinen, L-P, Macgregor, S, Mackey, DA, Mahajan, A, Mangino, M, Männistö, S, McCarthy, MI, McKnight, B, Medina-Gomez, C, Meigs, JB, Molnos, S, Mook-Kanamori, D, Morris, AP, De Mutsert, R, Nalls, MA, Nedeljkovic, I, North, KE, Pennell, CE, Pradhan, AD, Province, MA, Raitakari, OT, Raulerson, CK, Reiner, AP, Ridker, PM, Ripatti, S, Roberston, N, Rotter, JI, Salomaa, V, Sandoval-Zárate, AA, Sitlani, CM, Spector, TD, Strauch, K, Stumvoll, M, Taylor, KD, Thuesen, B, Tönjes, A, Uitterlinden, AG, Venturini, C, Walker, M, Wang, CA, Wang, S, Wareham, NJ, Willems, SM, Van Dijk, K, Wilson, JG, Wu, Y, Yao, J, Young, KL, Langenberg, C, Frayling, TM, Kilpeläinen, TO, Lindgren, CM, Loos, RJF, Mohlke, KL

Trans-ethnic association study of blood pressure determinants in over 750,000 individuals von Giri, A, Hellwege, JN, Keaton, JM, Park, J, Qiu, C, Warren, HR, Torstenson, ES, Kovesdy, CP, Sun, YV, Wilson, OD, Robinson-Cohen, C, Roumie, CL, Chung, CP, Birdwell, KA, Damrauer, SM, Duvall, SL, Klarin, D, Cho, K, Wang, Y, Evangelou, E, Cabrera, CP, Wain, LV, Shrestha, R, Mautz, BS, Akwo, EA, Sargurupremraj, M, Debette, S, Boehnke, M, Scott, LJ, Luan, J, Zhao, J-H, Willems, SM, Thériault, S, Shah, N, Oldmeadow, C, Almgren, P, Li-Gao, R, Verweij, N, Boutin, TS, Mangino, M, Ntalla, I, Feofanova, E, Surendran, P, Cook, JP, Karthikeyan, S, Lahrouchi, N, Liu, C, Sepúlveda, N, Richardson, TG, Kraja, A, Amouyel, P, Farrall, M, Poulter, NR, Understanding Society Scientific Group, International Consortium For Blood Pressure, Blood Pressure-International Consortium Of Exome Chip Studies, Laakso, M, Zeggini, E, Sever, P, Scott, RA, Langenberg, C, Wareham, NJ, Conen, D, Palmer, CNA, Attia, J, Chasman, DI, Ridker, PM, Melander, O, Mook-Kanamori, DO, Harst, PVD, Cucca, F, Schlessinger, D, Hayward, C, Spector, TD, Jarvelin, M-R, Hennig, BJ, Timpson, NJ, Wei, W-Q, Smith, JC, Xu, Y, Matheny, ME, Siew, EE, Lindgren, C, Herzig, K-H, Dedoussis, G, Denny, JC, Psaty, BM, Howson, JMM, Munroe, PB, Newton-Cheh, C, Caulfield, MJ, Elliott, P, Gaziano, JM, Concato, J, Wilson, PWF, Tsao, PS, Edwards, DR, Susztak, K, Million Veteran Program, O'Donnell, CJ, Hung, AM, Edwards, TL