Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction by Condon, Kendall J, Orozco, Jose M, Adelmann, Charles H, Spinelli, Jessica B, van der Helm, Pim W, Roberts, Justin M, Kunchok, Tenzin, Sabatini, David M

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Genome-wide CRISPR screens reveal multitiered mechanisms through which mTORC1 senses mitochondrial dysfunction by Condon, Kendall J., Orozco, Jose M., Adelmann, Charles H., Spinelli, Jessica B., van der Helm, Pim W., Roberts, Justin M., Kunchok, Tenzin, Sabatini, David M.

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Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance by van Gastel, Nick, Spinelli, Jessica B, Sharda, Azeem, Schajnovitz, Amir, Baryawno, Ninib, Rhee, Catherine, Oki, Toshihiko, Grace, Eliane, Soled, Heather J, Milosevic, Jelena, Sykes, David B, Hsu, Peggy P, Vander Heiden, Matthew G, Vidoudez, Charles, Trauger, Sunia A, Haigis, Marcia C, Scadden, David T

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Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance by van Gastel, Nick, Spinelli, Jessica B, Sharda, Azeem, Schajnovitz, Amir, Baryawno, Ninib, Rhee, Catherine, Oki, Toshihiko, Grace, Eliane, Soled, Heather J, Milosevic, Jelena, Sykes, David B, Hsu, Peggy P, Vander Heiden, Matthew G, Vidoudez, Charles, Trauger, Sunia A, Haigis, Marcia C, Scadden, David T

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The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance by Dall’Agnese, Alessandra, Platt, Jesse M, Zheng, Ming M, Friesen, Max, Dall’Agnese, Giuseppe, Blaise, Alyssa M, Spinelli, Jessica B, Henninger, Jonathan E, Tevonian, Erin N, Hannett, Nancy M, Lazaris, Charalampos, Drescher, Hannah K, Bartsch, Lea M, Kilgore, Henry R, Jaenisch, Rudolf, Griffith, Linda G, Cisse, Ibrahim I, Jeppesen, Jacob F, Lee, Tong I, Young, Richard A

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Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma by McBrayer, Samuel K., Mayers, Jared R., DiNatale, Gabriel J., Shi, Diana D., Khanal, Januka, Chakraborty, Abhishek A., Sarosiek, Kristopher A., Briggs, Kimberly J., Robbins, Alissa K., Sewastianik, Tomasz, Shareef, Sarah J., Olenchock, Benjamin A., Parker, Seth J., Tateishi, Kensuke, Spinelli, Jessica B., Islam, Mirazul, Haigis, Marcia C., Looper, Ryan E., Ligon, Keith L., Bernstein, Bradley E., Carrasco, Ruben D., Cahill, Daniel P., Asara, John M., Metallo, Christian M., Yennawar, Neela H., Vander Heiden, Matthew G., Kaelin, William G.

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