Role of tryptophan side chain dynamics on the Trp-cage mini-protein folding studied by molecular dynamics simulations. nork Srinivasaraghavan Kannan, Martin Zacharias

Testu osoa

Effect of Ser392 Phosphorylation on the Structure and Dynamics of the Polybasic Domain of ADP Ribosylation Factor Nucleotide Site Opener Protein: A Molecular Simulation Study nork Srinivasaraghavan, Kannan, Nacro, Kassoum, Grüber, Gerhard, Verma, Chandra Shekhar

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Testu osoa

Inhibiting S100B(ββ) for Activating Wild-Type p53: Design of Stapled Peptides nork Srinivasaraghavan Kannan, Pietro G. A. Aronica, Yaw Sing Tan, Chandra S. Verma

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JNK mediates cell death by promoting the ubiquitination of the apurinic/apyrimidinic endonuclease APE1 nork Bahareh Tabanifar, Anbalagan Moorthy, Heng Hang Tsai, Srinivasaraghavan Kannan, Chandra S. Verma, Kanaga Sabapathy

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Computational Design of Macrocyclic Binders of S100B(ββ): Novel Peptide Theranostics nork Srinivasaraghavan Kannan, Pietro G. A. Aronica, Thanh Binh Nguyen, Jianguo Li, Chandra S. Verma

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Disrupting the Dok3–Card9 Interaction with Synthetic Peptides Enhances Antifungal Effector Functions of Human Neutrophils nork Jia Tong Loh, Joey Kay Hui Teo, Srinivasaraghavan Kannan, Chandra S. Verma, Hong-Hwa Lim, Kong-Peng Lam

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Discovery of novel interacting partners of PSMD9, a proteasomal chaperone : role of an atypical and versatile PDZ-domain motif interaction and identification of putative functional... nork Sangith, Nikhil, Srinivasaraghavan, Kannan, Sahu, Indrajit, Desai, Ankita, Medipally, Spandana, Somavarappu, Arun Kumar, Verma, Chandra, Venkatraman, Prasanna

Testu osoa
Testu osoa

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513 nork Wong, Yee Hwa, Kumar, Akshita, Liew, Chong Wai, Tharakaraman, Kannan, Srinivasaraghavan, Kannan, Sasisekharan, Ram, Verma, Chandra, Lescar, Julien

Testu osoa
Testu osoa

Molecular basis for dengue virus broad cross-neutralization by humanized monoclonal antibody 513 nork Wong, Yee Hwa, Kumar, Akshita, Liew, Chong Wai, Tharakaraman, Kannan, Srinivasaraghavan, Kannan, Sasisekharan, Ram, Verma, Chandra, Lescar, Julien

Testu osoa
Testu osoa

Hydration effects on the efficacy of the Epidermal growth factor receptor kinase inhibitor afatinib nork Srinivasaraghavan Kannan, Mohan R. Pradhan, Garima Tiwari, Wei-Chong Tan, Balram Chowbay, Eng Huat Tan, Daniel Shao-Weng Tan, Chandra Verma

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Src activates retrograde membrane traffic through phosphorylation of GBF1 nork Joanne Chia, Shyi-Chyi Wang, Sheena Wee, David James Gill, Felicia Tay, Srinivasaraghavan Kannan, Chandra S Verma, Jayantha Gunaratne, Frederic A Bard

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Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences nork Jia Wei Siau, Asim Azhar Siddiqui, Sze Yi Lau, Srinivasaraghavan Kannan, Sabrina Peter, Yingying Zeng, Chandra Verma, Peter Droge, John F. Ghadessy

Testu osoa

Small Molecules Targeting the Inactive Form of the Mnk1/2 Kinases nork Srinivasaraghavan Kannan, Mohan R. Pradhan, Joseph Cherian, Thomas L. Joseph, Zhi Ying Poh, Yang Hai Yan, Ho Melvyn, Liu Boping, Hill Jeffrey, Kassoum Nacro, Chandra S. Verma

Testu osoa

Structural basis for the inhibition of histone deacetylase 8 (HDAC8), a key epigenetic player in the blood fluke Schistosoma mansoni. nork Martin Marek, Srinivasaraghavan Kannan, Alexander-Thomas Hauser, Marina Moraes Mourão, Stéphanie Caby, Vincent Cura, Diana A Stolfa, Karin Schmidtkunz, Julien Lancelot, Luiza Andrade, Jean-Paul Renaud, Guilherme Oliveira, Wolfgang Sippl, Manfred Jung, Jean Cavarelli, Raymond J Pierce, Christophe Romier

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A high‐throughput microfluidic mechanoporation platform to enable intracellular delivery of cyclic peptides in cell‐based assays nork Stephen H. Kasper, Stephanie Otten, Brian Squadroni, Cionna Orr‐Terry, Yi Kuang, Lily Mussallem, Lan Ge, Lin Yan, Srinivasaraghavan Kannan, Chandra S. Verma, Christopher J. Brown, Charles W. Johannes, David P. Lane, Arun Chandramohan, Anthony W. Partridge, Lee R. Roberts, Hubert Josien, Alex G. Therien, Erik C. Hett, Bonnie J. Howell, Andrea Peier, Xi Ai, Jason Cassaday

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Targeting codon 158 p53-mutant cancers via the induction of p53 acetylation nork Li Ren Kong, Richard Weijie Ong, Tuan Zea Tan, Nur Afiqah Binte Mohamed Salleh, Matan Thangavelu, Jane Vin Chan, Lie Yong Judice Koh, Giridharan Periyasamy, Jieying Amelia Lau, Thi Bich Uyen Le, Lingzhi Wang, Miyoung Lee, Srinivasaraghavan Kannan, Chandra S. Verma, Chwee Ming Lim, Wee Joo Chng, David P. Lane, Ashok Venkitaraman, Huynh The Hung, Chit Fang Cheok, Boon Cher Goh

Testu osoa

PARP4 interacts with hnRNPM to regulate splicing during lung cancer progression nork Yi Fei Lee, Cheryl Zi Jin Phua, Ju Yuan, Bin Zhang, May Yin Lee, Srinivasaraghavan Kannan, Yui Hei Jasper Chiu, Casslynn Wei Qian Koh, Choon Kong Yap, Edwin Kok Hao Lim, Jianbin Chen, Yuhua Lim, Jane Jia Hui Lee, Anders Jacobsen Skanderup, Zhenxun Wang, Weiwei Zhai, Nguan Soon Tan, Chandra S. Verma, Yvonne Tay, Daniel Shao Weng Tan, Wai Leong Tam

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Author Correction: Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists nork Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge

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Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists nork Arun Chandramohan, Hubert Josien, Tsz Ying Yuen, Ruchia Duggal, Diana Spiegelberg, Lin Yan, Yu-Chi Angela Juang, Lan Ge, Pietro G. Aronica, Hung Yi Kristal Kaan, Yee Hwee Lim, Andrea Peier, Brad Sherborne, Jerome Hochman, Songnian Lin, Kaustav Biswas, Marika Nestor, Chandra S. Verma, David P. Lane, Tomi K. Sawyer, Robert Garbaccio, Brian Henry, Srinivasaraghavan Kannan, Christopher J. Brown, Charles W. Johannes, Anthony W. Partridge

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A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma nork Li Ren Kong, Nur Afiqah Binte Mohamed Salleh, Richard Weijie Ong, Tuan Zea Tan, Nicholas L. Syn, Robby Miguel Goh, Chee Wai Fhu, Daniel S. W. Tan, N. Gopalakrishna Iyer, Srinivasaraghavan Kannan, Chandra S. Verma, Yaw Chyn Lim, Ross Soo, Jingshan Ho, Yiqing Huang, Joline S. J. Lim, Benedict Junrong Yan, Min En Nga, Seng Gee Lim, H. Phillip Koeffler, Soo Chin Lee, Dennis Kappei, Huynh The Hung, Boon Cher Goh

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