Beyond the Driver Mutation: Immunotherapies in Gastrointestinal Stromal Tumors by Matthieu Roulleaux Dugage, Robin Lewis Jones, Jonathan Trent, Stéphane Champiat, Sarah Dumont

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Anti-PD-1 Vasculitis of the central nervous system or radionecrosis? by Roger Sun, Francois-Xavier Danlos, Samy Ammari, Guillaume Louvel, Frédéric Dhermain, Stéphane Champiat, Olivier Lambotte, Eric Deutsch

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Relapsed and refractory classical Hodgkin lymphoma: could virotherapy help solve the equation? by Selma Addou, Clémentine Sarkozy, Julien Lazarovici, Stéphane Champiat, Aspasia Stamatoullas, Fabrice Jardin, Vincent Ribrag, Aurélien Marabelle, Jean-Marie Michot

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484 Preliminary efficacy of the IL-15 superagonist SO-C101 in combination with pembrolizumab in patients with advanced/metastatic solid tumors by Stephane Champiat, Aurélien Marabelle, Aung Naing, Filip Janku, Patricia LoRusso, David Béchard, Elena Garralda, Vladimir Galvao, Peter Grell, Richard Sachse, Joachim Kiemle-Kallee

715 ICT01 plus low dose SC IL-2 produces a robust anti-tumor immune activation in advanced cancer patients (EVICTION-2 Study) by Stephane Champiat, Francois-Xavier Danlos, Volker Kunzmann, Martin Wermke, Aude de Gassart, Daniel Olive, Patrick Brune, Emmanuel Valentin, Johann De Bono, Paul Frohna, Marina Iché, Maelle Mairesse, Celine Leparquier, Katrien Lemmens

Cardiovascular Toxicity Related to Cancer Treatment: A Pragmatic Approach to the American and European Cardio‐Oncology Guidelines by Joachim Alexandre, Jennifer Cautela, Stéphane Ederhy, Ghandi Laurent Damaj, Joe‐Elie Salem, Fabrice Barlesi, Laure Farnault, Aude Charbonnier, Mariana Mirabel, Stéphane Champiat, Alain Cohen‐Solal, Ariel Cohen, Charles Dolladille, Franck Thuny

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Predicting Immunotherapy Outcomes in Older Patients with Solid Tumors Using the LIPI Score by Monica Pierro, Capucine Baldini, Edouard Auclin, Hélène Vincent, Andreea Varga, Patricia Martin Romano, Perrine Vuagnat, Benjamin Besse, David Planchard, Antoine Hollebecque, Stéphane Champiat, Aurélien Marabelle, Jean-Marie Michot, Christophe Massard, Laura Mezquita

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Case Report: Response to Immunotherapy, Can Radiotherapy Be a Troublemaker? by Patricia Martin-Romano, Julien Adam, Jean-Yves Scoazec, Sébastien Gouy, Antonin Levy, Capucine Baldini, Stéphane Champiat, Jean-Charles Soria, Jean-Charles Soria, Jean-Charles Soria, Christophe Massard, Aurélien Marabelle, Eric Deutsch, Eric Deutsch, Eric Deutsch, Antoine Hollebecque

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Prognostic value of tumor immune biomarkers in biopsies from patients with refractory solid cancers by Tiphaine Lambert, Cedric Pobel, Léo Colmet-Daage, Amélie Bigorgne, Brice RaubyY, Nicolas Sanchez-Escobar Aladro, Lucile Ter-MinassianN, Marie Kerisit, Aurélien Marabelle, Benjamin Besse, Antoine Hollebecque, Stéphane Champiat, Christophe Massard, Daphné Morel, Loic Velringue, Jean-Yves Scoazec

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Society for Immunotherapy of Cancer (SITC) consensus definitions for immune checkpoint inhibitor-associated immune-related adverse events (irAEs) terminology by Laura C Cappelli, Maria E Suarez-Almazor, Michelle Turner, Stephane Champiat, Caroline Robert, Julie R Brahmer, Jarushka Naidoo, Jeffrey Weber, Joanne Riemer, Elad Sharon, Michael B Atkins, M Catherine Pietanza, Karthik Suresh, Catherine Murphy, Javid Moslehi, David Feltquate, Lee M Krug

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Human Endogenous Retrovirus Expression Is Upregulated in the Breast Cancer Microenvironment of HIV Infected Women: A Pilot Study by Gislaine Curty, Greta A. Beckerle, Luis P. Iñiguez, Robert L. Furler, Pedro S. de Carvalho, Jez L. Marston, Stephane Champiat, Jonas J. Heymann, Christopher E. Ormsby, Gustavo Reyes-Terán, Marcelo A. Soares, Douglas F. Nixon, Matthew L. Bendall, Fabio E. Leal, Miguel de Mulder Rougvie

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Abscopal Response in Metastatic Melanoma: Real-World Data of a Retrospective, Multicenter Study by Luc Ollivier, Charles Orione, Paul Bore, Laurent Misery, Delphine Legoupil, Jean-Christophe Leclere, Anne Coste, Gilles Girault, Iona Sicard-Cras, Clemence Kacperek, Francois Lucia, Dinu Stefan, François Thillays, Emmanuel Rio, Paul Lesueur, Christian Berthou, Dominique Heymann, Stéphane Champiat, Stéphane Supiot, Loig Vaugier, William Kao

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359 AMG 757, a half-life extended bispecific T-cell engager (BiTE®) immune therapy against DLL3 in SCLC: phase 1 interim results by Hui Yang, Stephane Champiat, Ramaswamy Govindan, Ravi Salgia, Fiona Blackhall, Everett Vokes, Michael Boyer, Marie-Anne Damiette Smit, Melissa Johnson, Hossein Borghaei, Luis Paz-Ares Rodrigues, Rene Boosman, Horst-Dieter Hummel, W Victoria Lai, Hibiki Udagawa, Anne Chiang, Christine Hann, Mukul Minocha, Nooshin Hashemi-Sadraei, Aditya Shetty, Taofeek Owonikoko

Influence of HAART on alternative reading frame immune responses over the course of HIV-1 infection. by Stephane Champiat, Rui André Saraiva Raposo, Nicholas J Maness, John L Lehman, Sean E Purtell, Aaron M Hasenkrug, Jacob C Miller, Hansi Dean, Wayne C Koff, Marisa Ailin Hong, Jeffrey N Martin, Steven G Deeks, Gerald E Spotts, Christopher D Pilcher, Fredrick M Hecht, Esper G Kallas, Keith E Garrison, Douglas F Nixon

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Safety, recommended dose, efficacy and immune correlates for nintedanib in combination with pembrolizumab in patients with advanced cancers by Capucine Baldini, Francois-Xavier Danlos, Andreea Varga, Matthieu Texier, Heloise Halse, Severine Mouraud, Lydie Cassard, Stéphane Champiat, Nicolas Signolle, Perrine Vuagnat, Patricia Martin-Romano, Jean-Marie Michot, Rastislav Bahleda, Anas Gazzah, Lisa Boselli, Delphine Bredel, Jonathan Grivel, Chifaou Mohamed-Djalim, Guillaume Escriou, Laetitia Grynszpan, Amelie Bigorgne, Saloomeh Rafie, Alae Abbassi, Vincent Ribrag, Sophie Postel-Vinay, Antoine Hollebecque, Sandrine Susini, Siham Farhane, Ludovic Lacroix, Aurelien Parpaleix, Salim Laghouati, Laurence Zitvogel, Julien Adam, Nathalie Chaput, Jean-Charles Soria, Christophe Massard, Aurelien Marabelle

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First-in-human phase I study of the OX40 agonist GSK3174998 with or without pembrolizumab in patients with selected advanced solid tumors (ENGAGE-1) by Stephane Champiat, Aurélien Marabelle, Anna Spreafico, Mehmet Altan, Todd M Bauer, Osama Rahma, Karen A Autio, Neeta Somaiah, Meredith McKean, Aaron R Hansen, Jan H M Schellens, Willeke Ros, F Stephen Hodi, Jeffrey S Weber, John V Heymach, Herbert Struemper, Sandrine Aspeslagh, Daniel C Cho, Jennifer K Litton, Axel Hoos, Vincent K Lam, Emmett V Schmidt, Sophie Postel-Vinay, Frans L Opdam, Elaine M Paul, Christoph M Ahlers, Helen Zhou, Shelby A Gorman, Maura Watmuff, Kaitlin M Yablonski, Niranjan Yanamandra, Michael J Chisamore

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716 Phase 2 study of the HER2-targeting TLR7/8 immune stimulating antibody conjugate (ISAC) BDC-1001 monotherapy +/- nivolumab in patients with HER2+ colorectal, endometrial, or ga... by Jean-Yves Blay, Antoine Italiano, Stephane Champiat, Paolo Antonio Ascierto, Manish Sharma, Jeeyun Lee, Luis Paz-Ares Rodriguez, Keun-Wook Lee, Yoon-Koo Kang, Drew Rasco, Edith A Perez, Mariano Ponz-Sarvise, Lu Xu, Jean-Philippe Spano, Coya Tapia, Ecaterina Dumbrava, Kathleen Moore, Jason Ptacek, Michele Magni, Alfonso Cortes Salgado, Ming Yin, Agnese Losurdo, Antoine Deleuze, Mark D Pegram, Ardaman Shergill, Alexander I Spira, Michael N Alonso, Joan Albanell Mestres, Marta GilMartin, Arielle Heeke, Ana Oaknin Benzaquen, Ignacio Ortego Zabalza, Haeseong Park, Cecile Vicier, Ivan Victoria, Benjamin Weinberg, Bob T Li