EXPRESSION OF LYSOZYME IN INFLAMMATORY BOWEL-DISEASE Por Stamp, G, Keshav, S, Chung, P, Wright, N

Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma. Por Foulkes, W, Ragoussis, I, Stamp, G, Allan, G, Trowsdale, J

Raf signaling but not the ERK effector SAP-1 is required for regulatory T cell development. Por Willoughby, J, Costello, P, Nicolas, R, Robinson, N, Stamp, G, Powrie, F, Treisman, R

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development Por Davis, H, Lewis, A, Spencer-Dene, B, Tateossian, H, Stamp, G, Behrens, A, Tomlinson, I

E-cadherin/catenin complex status in solid pseudopapillary tumor of the pancreas. Por El-Bahrawy, M, Rowan, A, Horncastle, D, Tomlinson, I, Theis, B, Russell, R, Stamp, G

Lysozyme gene expression in inflammatory bowel disease. Por Stamp, G, Poulsom, R, Chung, L, Keshav, S, Jeffery, R, Longcroft, J, Pignatelli, M, Wright, N

FBXW7 mutations typically found in human cancers are distinct from null alleles and disrupt lung development. Por Davis, H, Lewis, A, Spencer-Dene, B, Tateossian, H, Stamp, G, Behrens, A, Tomlinson, I

The C-terminus of Apc does not influence intestinal adenoma development or progression Por Lewis, A, Davis, H, Deheragoda, M, Pollard, P, Nye, E, Jeffery, R, Segditsas, S, East, P, Poulsom, R, Stamp, G, Wright, N, Tomlinson, I

The C-terminus of Apc does not influence intestinal adenoma development or progression. Por Lewis, A, Davis, H, Deheragoda, M, Pollard, P, Nye, E, Jeffery, R, Segditsas, S, East, P, Poulsom, R, Stamp, G, Wright, N, Tomlinson, I

Severe polyposis in Apc1322T mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5 Por Lewis, A, Segditsas, S, Deheragoda, M, Pollard, P, Jeffery, R, Nye, E, Lockstone, H, Davis, H, Clark, S, Stamp, G, Poulsom, R, Wright, N, Tomlinson, I

Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5. Por Lewis, A, Segditsas, S, Deheragoda, M, Pollard, P, Jeffery, R, Nye, E, Lockstone, H, Davis, H, Clark, S, Stamp, G, Poulsom, R, Wright, N, Tomlinson, I

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice. Por Segditsas, S, Sieber, O, Deheragoda, M, East, P, Rowan, A, Jeffery, R, Nye, E, Clark, S, Spencer-Dene, B, Stamp, G, Poulsom, R, Suraweera, N, Silver, A, Ilyas, M, Tomlinson, I

Expression of HIF-1alpha, HIF-2alpha (EPAS1), and their target genes in paraganglioma and pheochromocytoma with VHL and SDH mutations. Por Pollard, P, El-Bahrawy, M, Poulsom, R, Elia, G, Killick, P, Kelly, G, Hunt, T, Jeffery, R, Seedhar, P, Barwell, J, Latif, F, Gleeson, M, Hodgson, S, Stamp, G, Tomlinson, I, Maher, E

Myh deficiency enhances intestinal tumorigenesis in multiple intestinal neoplasia (ApcMin/+) mice. Por Sieber, O, Howarth, K, Thirlwell, C, Rowan, A, Mandir, N, Goodlad, R, Gilkar, A, Spencer-Dene, B, Stamp, G, Johnson, V, Silver, A, Yang, H, Miller, J, Ilyas, M, Tomlinson, I

Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Por Pollard, P, Spencer-Dene, B, Shukla, D, Howarth, K, Nye, E, El-Bahrawy, M, Deheragoda, M, Joannou, M, McDonald, S, Martin, A, Igarashi, P, Varsani-Brown, S, Rosewell, I, Poulsom, R, Maxwell, P, Stamp, G, Tomlinson, I

The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression. Por Pollard, P, Deheragoda, M, Segditsas, S, Lewis, A, Rowan, A, Howarth, K, Willis, L, Nye, E, McCart, A, Mandir, N, Silver, A, Goodlad, R, Stamp, G, Cockman, M, East, P, Spencer-Dene, B, Poulsom, R, Wright, N, Tomlinson, I

Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. Por Adam, J, Hatipoglu, E, O'Flaherty, L, Ternette, N, Sahgal, N, Lockstone, H, Baban, D, Nye, E, Stamp, G, Wolhuter, K, Stevens, M, Fischer, R, Carmeliet, P, Maxwell, P, Pugh, C, Frizzell, N, Soga, T, Kessler, B, El-Bahrawy, M, Ratcliffe, P, Pollard, P

BCL9L dysfunction impairs caspase-2 expression permitting aneuploidy tolerance in colorectal cancer. Por López-García, C, Sansregret, L, Domingo, E, McGranahan, N, Hobor, S, Birkbak, N, Horswell, S, Grönroos, E, Favero, F, Rowan, A, Matthews, N, Begum, S, Phillimore, B, Burrell, R, Oukrif, D, Spencer-Dene, B, Kovac, M, Stamp, G, Stewart, A, Danielsen, H, Novelli, M, Tomlinson, I, Swanton, C

Inhibition of fatty acid desaturation is detrimental to cancer cell survival in metabolically compromised environments Por Peck, B, Schug, Z, Zhang, Q, Dankworth, B, Jones, D, Smethurst, E, Patel, R, Mason, S, Jiang, M, Saunders, R, Howell, M, Mitter, R, Spencer-Dene, B, Stamp, G, McGarry, L, James, D, Shanks, E, Aboagye, E, Critchlow, S, Leung, H, Harris, A, Wakelam, M, Gottlieb, E, Schulze, A

Expression profiling in progressive stages of fumarate-hydratase deficiency: the contribution of metabolic changes to tumorigenesis. Por Ashrafian, H, O'Flaherty, L, Adam, J, Steeples, V, Chung, Y, East, P, Vanharanta, S, Lehtonen, H, Nye, E, Hatipoglu, E, Miranda, M, Howarth, K, Shukla, D, Troy, H, Griffiths, J, Spencer-Dene, B, Yusuf, M, Volpi, E, Maxwell, P, Stamp, G, Poulsom, R, Pugh, C, Costa, B, Bardella, C, Di Renzo, M