Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics by Matteo Calligaris, Matteo Calligaris, Chun Y. Yang, Simone Bonelli, Simone Bonelli, Donatella Pia Spanò, Donatella Pia Spanò, Stephan A. Müller, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra

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QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain by Sharon C. Yates, Nicolaas E. Groeneboom, Christopher Coello, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Peer-Hendrik Kuhn, Hans-Ulrich Demuth, Maike Hartlage-Rübsamen, Steffen Roßner, Trygve Leergaard, Anna Kreshuk, Maja A. Puchades, Jan G. Bjaalie

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An Alzheimer‐associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function by Kai Schlepckow, Gernot Kleinberger, Akio Fukumori, Regina Feederle, Stefan F Lichtenthaler, Harald Steiner, Christian Haass

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Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons by Rohit Kumar, Sainitin Donakonda, Stephan A. Müller, Stefan F. Lichtenthaler, Kai Bötzel, Günter U. Höglinger, Thomas Koeglsperger

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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls by Ida Pesämaa, Stephan A. Müller, Sophie Robinson, Alana Darcher, Dominik Paquet, Henrik Zetterberg, Stefan F. Lichtenthaler, Christian Haass

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NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease by Tobias Brummer, Stephan A Müller, Francisco Pan‐Montojo, Fumiaki Yoshida, Andreas Fellgiebel, Taisuke Tomita, Kristina Endres, Stefan F Lichtenthaler

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Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase by Nadine T. Werner, Philipp Högel, Gökhan Güner, Walter Stelzer, Manfred Wozny, Marlene Aßfalg, Stefan F. Lichtenthaler, Harald Steiner, Dieter Langosch

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Reactivated endogenous retroviruses promote protein aggregate spreading by Shu Liu, Stefanie-Elisabeth Heumüller, André Hossinger, Stephan A. Müller, Oleksandra Buravlova, Stefan F. Lichtenthaler, Philip Denner, Ina M. Vorberg

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Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State by Chun-Yao Yang, Simone Bonelli, Matteo Calligaris, Anna Paola Carreca, Stephan A. Müller, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra

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Author Correction: Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2 by Karsten Nalbach, Martina Schifferer, Debjani Bhattacharya, Hung Ho-Xuan, Wei Chou Tseng, Luis A. Williams, Alexandra Stolz, Stefan F. Lichtenthaler, Zvulun Elazar, Christian Behrends

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Generation and deposition of Aβ43 by the virtually inactive presenilin‐1 L435F mutant contradicts the presenilin loss‐of‐function hypothesis of Alzheimer's disease by Benedikt Kretner, Johannes Trambauer, Akio Fukumori, Janina Mielke, Peer‐Hendrik Kuhn, Elisabeth Kremmer, Armin Giese, Stefan F Lichtenthaler, Christian Haass, Thomas Arzberger, Harald Steiner

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Spatial proteomics reveals secretory pathway disturbances caused by neuropathy-associated TECPR2 by Karsten Nalbach, Martina Schifferer, Debjani Bhattacharya, Hung Ho-Xuan, Wei Chou Tseng, Luis A. Williams, Alexandra Stolz, Stefan F. Lichtenthaler, Zvulun Elazar, Christian Behrends

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PERK activation mitigates tau pathology in vitro and in vivo by Julius Bruch, Hong Xu, Thomas W Rösler, Anderson De Andrade, Peer‐Hendrik Kuhn, Stefan F Lichtenthaler, Thomas Arzberger, Konstanze F Winklhofer, Ulrich Müller, Günter U Höglinger

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The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130 by Stephan A. Müller, Merav D. Shmueli, Xiao Feng, Johanna Tüshaus, Neele Schumacher, Ryan Clark, Brad E. Smith, An Chi, Stefan Rose-John, Matthew E. Kennedy, Stefan F. Lichtenthaler

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Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation by Maike Hartlage-Rübsamen, Alexandra Bluhm, Anke Piechotta, Miriam Linnert, Jens-Ulrich Rahfeld, Hans-Ulrich Demuth, Inge Lues, Peer-Hendrik Kuhn, Stefan F. Lichtenthaler, Steffen Roßner, Corinna Höfling

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Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage by Alkmini A. Papadopoulou, Walter Stelzer, Mara Silber, Christine Schlosser, Charlotte Spitz, Martina Haug-Kröper, Tobias Straub, Stephan A. Müller, Stefan F. Lichtenthaler, Claudia Muhle-Goll, Dieter Langosch, Regina Fluhrer

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Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover by Seda Yasa, Elisabeth S. Butz, Alessio Colombo, Uma Chandrachud, Luca Montore, Sarah Tschirner, Matthias Prestel, Steven D. Sheridan, Stephan A. Müller, Janos Groh, Stefan F. Lichtenthaler, Sabina Tahirovic, Susan L. Cotman

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Soluble form of Lingo2, an autism spectrum disorder-associated molecule, functions as an excitatory synapse organizer in neurons by Fumiaki Yoshida, Ryota Nagatomo, Shun Utsunomiya, Misaki Kimura, Shiyori Shun, Rena Kono, Yuma Kato, Yosuke Nao, Kazuma Maeda, Ryuta Koyama, Yuji Ikegaya, Stefan F. Lichtenthaler, Sho Takatori, Hiroshi Takemoto, Koichi Ogawa, Genta Ito, Taisuke Tomita

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Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models by Laura Sebastian Monasor, Stephan A Müller, Alessio Vittorio Colombo, Gaye Tanrioever, Jasmin König, Stefan Roth, Arthur Liesz, Anna Berghofer, Anke Piechotta, Matthias Prestel, Takashi Saito, Takaomi C Saido, Jochen Herms, Michael Willem, Christian Haass, Stefan F Lichtenthaler, Sabina Tahirovic

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Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity by Gökhan Güner, Marlene Aßfalg, Kai Zhao, Tobias Dreyer, Shibojyoti Lahiri, Yun Lo, Bianca Ionela Slivinschi, Axel Imhof, Georg Jocher, Laura Strohm, Christian Behrends, Dieter Langosch, Holger Bronger, Christopher Nimsky, Jörg W Bartsch, Stanley R Riddell, Harald Steiner, Stefan F Lichtenthaler

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