IDH mutation, glioma immunogenicity, and therapeutic challenge of primary mismatch repair deficient IDH‐mutant astrocytoma PMMRDIA: a systematic review by Olfat Ahmad, Tahani Ahmad, Stefan M. Pfister

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BRCA1/2 potential founder variants in the Jordanian population: an opportunity for a customized screening panel by Olfat Ahmad, Christian Sutter, Steffen Hirsch, Stefan M. Pfister, Christian P. Schaaf

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Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics by Salvatore Benfatto, Martin Sill, David T. W. Jones, Stefan M. Pfister, Felix Sahm, Andreas von Deimling, David Capper, Volker Hovestadt

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Important Requirements for the Selection of Internal Standards during the Development of Desorption/Ionization Assays for Drug Quantification in Biological Matrices—A Practical Exa... by Margaux Fresnais, Seda Karabulut, Yasmin Abou Zeed, Johannes Ungermann, Julia Benzel, Kristian W. Pajtler, Stefan M. Pfister, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée

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Comparison of transcriptome profiles between medulloblastoma primary and recurrent tumors uncovers novel variance effects in relapses by Konstantin Okonechnikov, Aniello Federico, Daniel Schrimpf, Philipp Sievers, Felix Sahm, Jan Koster, David T. W. Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool, Andrey Korshunov

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Rapid MALDI-MS Assays for Drug Quantification in Biological Matrices: Lessons Learned, New Developments, and Future Perspectives by Margaux Fresnais, Esra Yildirim, Seda Karabulut, Dirk Jäger, Inka Zörnig, Julia Benzel, Kristian W. Pajtler, Stefan M. Pfister, Jürgen Burhenne, Walter E. Haefeli, Rémi Longuespée

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Heterogeneity of DNA methylation profiles and copy number alterations in 10782 adult-type glioblastomas, IDH-wildtype by David E. Reuss, Daniel Schrimpf, Asan Cherkezov, Abigail K. Suwala, Tereza Lausová, Matija Snuderl, David Capper, Martin Sill, David T. W. Jones, Stefan M. Pfister, Felix Sahm, Andreas von Deimling

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Proteomic analysis of Medulloblastoma reveals functional biology with translational potential by Samuel Rivero-Hinojosa, Ling San Lau, Mojca Stampar, Jerome Staal, Huizhen Zhang, Heather Gordish-Dressman, Paul A. Northcott, Stefan M. Pfister, Michael D. Taylor, Kristy J. Brown, Brian R. Rood

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Reference on copy number variations in pleomorphic xanthoastrocytoma: Implications for diagnostic approach by David E. Reuss, Daniel Schrimpf, Damian Stichel, Azadeh Ebrahimi, Chris Dampier, Kenneth Aldape, Matija Snuderl, David Capper, Martin Sill, David T.W. Jones, Stefan M. Pfister, Sahm Felix, Andreas von Deimling

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Infection as a cause of childhood leukemia: virus detection employing whole genome sequencing by Christoph Bartenhagen, Ute Fischer, Klaus Korn, Stefan M. Pfister, Michael Gombert, Cai Chen, Vera Okpanyi, Julia Hauer, Anna Rinaldi, Jean-Pierre Bourquin, Cornelia Eckert, Jianda Hu, Armin Ensser, Martin Dugas, Arndt Borkhardt

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A cell‐based model system links chromothripsis with hyperploidy by Balca R Mardin, Alexandros P Drainas, Sebastian M Waszak, Joachim Weischenfeldt, Mayumi Isokane, Adrian M Stütz, Benjamin Raeder, Theocharis Efthymiopoulos, Christopher Buccitelli, Maia Segura‐Wang, Paul Northcott, Stefan M Pfister, Peter Lichter, Jan Ellenberg, Jan O Korbel

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Analytical Performance Evaluation of New DESI Enhancements for Targeted Drug Quantification in Tissue Sections by Margaux Fresnais, Siwen Liang, Marius Breitkopf, Joshua Raoul Lindner, Emmanuelle Claude, Steven Pringle, Pavel A. Levkin, Konstantin Demir, Julia Benzel, Julia Sundheimer, Britta Statz, Kristian W. Pajtler, Stefan M. Pfister, Walter E. Haefeli, Jürgen Burhenne, Rémi Longuespée

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Biglycan-driven risk stratification in ZFTA-RELA fusion supratentorial ependymomas through transcriptome profiling by Konstantin Okonechnikov, David R. Ghasemi, Daniel Schrimpf, Svenja Tonn, Martin Mynarek, Jan Koster, Till Milde, Tuyu Zheng, Philipp Sievers, Felix Sahm, David T.W. Jones, Andreas von Deimling, Stefan M. Pfister, Marcel Kool, Kristian W. Pajtler, Andrey Korshunov

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EGFL7 enhances surface expression of integrin α5β1 to promote angiogenesis in malignant brain tumors by Nevenka Dudvarski Stanković, Frank Bicker, Stefanie Keller, David TW Jones, Patrick N Harter, Arne Kienzle, Clarissa Gillmann, Philipp Arnold, Anna Golebiewska, Olivier Keunen, Alf Giese, Andreas von Deimling, Tobias Bäuerle, Simone P Niclou, Michel Mittelbronn, Weilan Ye, Stefan M Pfister, Mirko HH Schmidt

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Downregulation of miR‐326 and its host gene β‐arrestin1 induces pro‐survival activity of E2F1 and promotes medulloblastoma growth by Evelina Miele, Agnese Po, Angela Mastronuzzi, Andrea Carai, Zein Mersini Besharat, Natalia Pediconi, Luana Abballe, Giuseppina Catanzaro, Claudia Sabato, Enrico De Smaele, Gianluca Canettieri, Lucia Di Marcotullio, Alessandra Vacca, Antonello Mai, Massimo Levrero, Stefan M. Pfister, Marcel Kool, Felice Giangaspero, Franco Locatelli, Elisabetta Ferretti

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Spatio-temporal transcriptomics of chromothriptic SHH-medulloblastoma identifies multiple genetic clones that resist treatment and drive relapse by Ilia Kats, Milena Simovic-Lorenz, Hannah Sophia Schreiber, Pooja Sant, Jan-Philipp Mallm, Verena Körber, Albert Li, Pravin Velmurugan, Sophie Heuer, Luisa Kües, Frauke Devens, Martin Sill, Manfred Jugold, Mahmoud Moustafa, Amir Abdollahi, Frank Winkler, Andrey Korshunov, Stefan M. Pfister, Oliver Stegle, Aurélie Ernst

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Overview of European standard clinical practice recommendations for multidiscplinary teams involved in the treatment of central nervous system tumours in children and adolescents –... by Maria Otth, Katrin Scheinemann, Thankamma Ajithkumar, Kristian Aquilina, Shivaram Avula, Hoong-Wei Gan, Geert O. Janssens, Jurgen Lemiere, Giovanni Morana, Enrico Opocher, Stefan M. Pfister, Giorgio Porro, Felix Sahm, Ulrich-Wilhelm Thomale, Michelle van Egmond-Ebbeling, Hanneke M. van Santen, Barry Pizer, Stefan Rutkowski

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Mitochondrial DNA mutations in Medulloblastoma by Viktoria L. E. Funke, Sarah Sandmann, Viktoria Melcher, Jochen Seggewiss, Judit Horvath, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Stefan Rutkowski, Martin Mynarek, Julian Varghese, Ronald Sträter, Stephan Rust, Anja Seelhöfer, Janine Reunert, Barbara Fiedler, Ulrich Schüller, Thorsten Marquardt, Kornelius Kerl

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Group-specific cellular metabolism in Medulloblastoma by Viktoria L. E. Funke, Carolin Walter, Viktoria Melcher, Lanying Wei, Sarah Sandmann, Marc Hotfilder, Julian Varghese, Natalie Jäger, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Till Milde, Martin Mynarek, Stefan Rutkowski, Jochen Seggewiss, Daniela Jeising, Flavia W. de Faria, Thorsten Marquardt, Thomas K. Albert, Ulrich Schüller, Kornelius Kerl

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Loss of phosphatase CTDNEP1 potentiates aggressive medulloblastoma by triggering MYC amplification and genomic instability by Zaili Luo, Dazhuan Xin, Yunfei Liao, Kalen Berry, Sean Ogurek, Feng Zhang, Liguo Zhang, Chuntao Zhao, Rohit Rao, Xinran Dong, Hao Li, Jianzhong Yu, Yifeng Lin, Guoying Huang, Lingli Xu, Mei Xin, Ryuichi Nishinakamura, Jiyang Yu, Marcel Kool, Stefan M. Pfister, Martine F. Roussel, Wenhao Zhou, William A. Weiss, Paul Andreassen, Q. Richard Lu

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