Showing 1 - 13 results of 13 for search 'Stefano Mangani', query time: 0.04s Refine Results
  1. 1
    Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors

    Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors by Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Maria Paola Costi, Stefano Mangani

    Published 2019-04-01
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  2. 2
    Structural Comparison of <i>Enterococcus faecalis</i> and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities

    Structural Comparison of <i>Enterococcus faecalis</i> and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformati... by Cecilia Pozzi, Stefania Ferrari, Rosaria Luciani, Giusy Tassone, Maria Paola Costi, Stefano Mangani

    Published 2019-03-01
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  3. 3
    Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor

    Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor by Giusy Tassone, Marco Mazzorana, Stefano Mangani, Elena Petricci, Elena Cini, Giuseppe Giannini, Cecilia Pozzi, Samuele Maramai

    Published 2022-08-01
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  4. 4
    Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of <i>Trypanosoma brucei</i> Pteridine Reductase and Dihydrofolate Reductase

    Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of <i>Trypanosoma brucei</i> Pteridine Reductase and Dihydrofolate Reductase by Giusy Tassone, Giacomo Landi, Pasquale Linciano, Valeria Francesconi, Michele Tonelli, Lorenzo Tagliazucchi, Maria Paola Costi, Stefano Mangani, Cecilia Pozzi

    Published 2021-06-01
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  5. 5
    Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML

    Small Molecules as Potential Inhibitors of the 14-3-3/c-Abl Interaction for the Treatment of CML by Leire Iralde-Lorente, Giusy Tassone, Ylenia Cau, Claire Munier, Lorenzo Franci, Cecilia Pozzi, Adriano Angelucci, Mario Chiariello, Matthew Perry, Stefano Mangani, Maurizio Botta

    Published 2019-08-01
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  6. 6
    On Nature's Strategy for Assigning Genetic Code Multiplicity.

    On Nature's Strategy for Assigning Genetic Code Multiplicity. by Simone Gardini, Sara Cheli, Silvia Baroni, Gabriele Di Lascio, Guido Mangiavacchi, Nicholas Micheletti, Carmen Luigia Monaco, Lorenzo Savini, Davide Alocci, Stefano Mangani, Neri Niccolai

    Published 2016-01-01
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  7. 7
    Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases

    Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases by Matteo Santucci, Rosaria Luciani, Eleonora Gianquinto, Cecilia Pozzi, Flavio di Pisa, Lucia dello Iacono, Giacomo Landi, Lorenzo Tagliazucchi, Stefano Mangani, Francesca Spyrakis, Maria Paola Costi

    Published 2021-11-01
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  8. 8
    Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

    Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations by Cecilia Pozzi, Matteo Santucci, Gaetano Marverti, Domenico D’Arca, Lorenzo Tagliazucchi, Stefania Ferrari, Gaia Gozzi, Lorena Losi, Giusy Tassone, Stefano Mangani, Glauco Ponterini, Maria Paola Costi

    Published 2021-04-01
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  9. 9
    Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment

    Copper Binding and Redox Activity of α-Synuclein in Membrane-Like Environment by Chiara Bacchella, Francesca Camponeschi, Paulina Kolkowska, Arian Kola, Isabella Tessari, Maria Camilla Baratto, Marco Bisaglia, Enrico Monzani, Luigi Bubacco, Stefano Mangani, Luigi Casella, Simone Dell’Acqua, Daniela Valensin

    Published 2023-02-01
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  10. 10
    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery

    Exploiting the 2‑Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery by Pasquale Linciano, Alice Dawson, Ina Pöhner, David M. Costa, Monica S. Sá, Anabela Cordeiro-da-Silva, Rosaria Luciani, Sheraz Gul, Gesa Witt, Bernhard Ellinger, Maria Kuzikov, Philip Gribbon, Jeanette Reinshagen, Markus Wolf, Birte Behrens, Véronique Hannaert, Paul A. M. Michels, Erika Nerini, Cecilia Pozzi, Flavio di Pisa, Giacomo Landi, Nuno Santarem, Stefania Ferrari, Puneet Saxena, Sandra Lazzari, Giuseppe Cannazza, Lucio H. Freitas-Junior, Carolina B. Moraes, Bruno S. Pascoalino, Laura M. Alcântara, Claudia P. Bertolacini, Vanessa Fontana, Ulrike Wittig, Wolfgang Müller, Rebecca C. Wade, William N. Hunter, Stefano Mangani, Luca Costantino, Maria P. Costi

    Published 2017-09-01
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  11. 11
    Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth

    Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth by Luca Costantino, Stefania Ferrari, Matteo Santucci, Outi MH Salo-Ahen, Emanuele Carosati, Silvia Franchini, Angela Lauriola, Cecilia Pozzi, Matteo Trande, Gaia Gozzi, Puneet Saxena, Giuseppe Cannazza, Lorena Losi, Daniela Cardinale, Alberto Venturelli, Antonio Quotadamo, Pasquale Linciano, Lorenzo Tagliazucchi, Maria Gaetana Moschella, Remo Guerrini, Salvatore Pacifico, Rosaria Luciani, Filippo Genovese, Stefan Henrich, Silvia Alboni, Nuno Santarem, Anabela da Silva Cordeiro, Elisa Giovannetti, Godefridus J Peters, Paolo Pinton, Alessandro Rimessi, Gabriele Cruciani, Robert M Stroud, Rebecca C Wade, Stefano Mangani, Gaetano Marverti, Domenico D'Arca, Glauco Ponterini, Maria Paola Costi

    Published 2022-12-01
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  12. 12
    Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6

    Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6 by Jean Jacques Vanden Eynde, Arduino A. Mangoni, Jarkko Rautio, Jérôme Leprince, Yasu-Taka Azuma, Alfonso T. García-Sosa, Christopher Hulme, Josef Jampilek, Rafik Karaman, Wei Li, Paula A. C. Gomes, Dimitra Hadjipavlou-Litina, Raffaele Capasso, Athina Geronikaki, Laura Cerchia, Jean-Marc Sabatier, Rino Ragno, Tiziano Tuccinardi, Andrea Trabocchi, Jean-Yves Winum, F. Javier Luque, Katalin Prokai-Tatrai, Mariana Spetea, Michael Gütschow, Ivan Kosalec, Catherine Guillou, M. Helena Vasconcelos, George Kokotos, Giulio Rastelli, Maria Emília de Sousa, Clementina Manera, Sandra Gemma, Stefano Mangani, Carlo Siciliano, Stefania Galdiero, Hong Liu, Peter J. H. Scott, Cristóbal de los Ríos, Luigi A. Agrofoglio, Simona Collina, Rita C. Guedes, Diego Muñoz-Torrero

    Published 2019-12-01
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  13. 13
    Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7

    Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7 by Michael Gütschow, Jean Jacques Vanden Eynde, Josef Jampilek, CongBao Kang, Arduino A. Mangoni, Paola Fossa, Rafik Karaman, Andrea Trabocchi, Peter J. H. Scott, Jóhannes Reynisson, Simona Rapposelli, Stefania Galdiero, Jean-Yves Winum, Chiara Brullo, Katalin Prokai-Tatrai, Arun K. Sharma, Matthieu Schapira, Yasu-Taka Azuma, Laura Cerchia, Mariana Spetea, Giangiacomo Torri, Simona Collina, Athina Geronikaki, Alfonso T. García-Sosa, M. Helena Vasconcelos, Maria Emília Sousa, Ivan Kosalec, Tiziano Tuccinardi, Iola F. Duarte, Jorge A. R. Salvador, Massimo Bertinaria, Maurizio Pellecchia, Jussara Amato, Giulio Rastelli, Paula A. C. Gomes, Rita C. Guedes, Jean-Marc Sabatier, Ana Estévez-Braun, Bruno Pagano, Stefano Mangani, Rino Ragno, George Kokotos, Margherita Brindisi, Florenci V. González, Fernanda Borges, Mariarosaria Miloso, Jarkko Rautio, Diego Muñoz-Torrero

    Published 2020-06-01
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