Proteomic Substrate Identification for Membrane Proteases in the Brain by Stephan A Müller, Simone D Scilabra, Stefan F Lichtenthaler

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Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons by Rohit Kumar, Sainitin Donakonda, Stephan A. Müller, Stefan F. Lichtenthaler, Kai Bötzel, Günter U. Höglinger, Thomas Koeglsperger

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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer’s disease patients from controls by Ida Pesämaa, Stephan A. Müller, Sophie Robinson, Alana Darcher, Dominik Paquet, Henrik Zetterberg, Stefan F. Lichtenthaler, Christian Haass

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NrCAM is a marker for substrate‐selective activation of ADAM10 in Alzheimer's disease by Tobias Brummer, Stephan A Müller, Francisco Pan‐Montojo, Fumiaki Yoshida, Andreas Fellgiebel, Taisuke Tomita, Kristina Endres, Stefan F Lichtenthaler

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Reactivated endogenous retroviruses promote protein aggregate spreading by Shu Liu, Stefanie-Elisabeth Heumüller, André Hossinger, Stephan A. Müller, Oleksandra Buravlova, Stefan F. Lichtenthaler, Philip Denner, Ina M. Vorberg

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Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State by Chun-Yao Yang, Simone Bonelli, Matteo Calligaris, Anna Paola Carreca, Stephan A. Müller, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra

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FGF2 Affects Parkinson’s Disease-Associated Molecular Networks Through Exosomal Rab8b/Rab31 by Rohit Kumar, Rohit Kumar, Rohit Kumar, Sainitin Donakonda, Stephan A. Müller, Kai Bötzel, Günter U. Höglinger, Günter U. Höglinger, Günter U. Höglinger, Thomas Koeglsperger, Thomas Koeglsperger

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The Alzheimer’s disease-linked protease BACE1 modulates neuronal IL-6 signaling through shedding of the receptor gp130 by Stephan A. Müller, Merav D. Shmueli, Xiao Feng, Johanna Tüshaus, Neele Schumacher, Ryan Clark, Brad E. Smith, An Chi, Stefan Rose-John, Matthew E. Kennedy, Stefan F. Lichtenthaler

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Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage by Alkmini A. Papadopoulou, Walter Stelzer, Mara Silber, Christine Schlosser, Charlotte Spitz, Martina Haug-Kröper, Tobias Straub, Stephan A. Müller, Stefan F. Lichtenthaler, Claudia Muhle-Goll, Dieter Langosch, Regina Fluhrer

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Loss of CLN3 in microglia leads to impaired lipid metabolism and myelin turnover by Seda Yasa, Elisabeth S. Butz, Alessio Colombo, Uma Chandrachud, Luca Montore, Sarah Tschirner, Matthias Prestel, Steven D. Sheridan, Stephan A. Müller, Janos Groh, Stefan F. Lichtenthaler, Sabina Tahirovic, Susan L. Cotman

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Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions by Shu Liu, André Hossinger, Stefanie-Elisabeth Heumüller, Annika Hornberger, Oleksandra Buravlova, Katerina Konstantoulea, Stephan A. Müller, Lydia Paulsen, Frederic Rousseau, Joost Schymkowitz, Stefan F. Lichtenthaler, Manuela Neumann, Philip Denner, Ina M. Vorberg

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Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics by Matteo Calligaris, Matteo Calligaris, Chun Y. Yang, Simone Bonelli, Simone Bonelli, Donatella Pia Spanò, Donatella Pia Spanò, Stephan A. Müller, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Stefan F. Lichtenthaler, Linda Troeberg, Simone D. Scilabra

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Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia by Alessio Colombo, Lina Dinkel, Stephan A. Müller, Laura Sebastian Monasor, Martina Schifferer, Ludovico Cantuti-Castelvetri, Jasmin König, Lea Vidatic, Tatiana Bremova-Ertl, Andrew P. Lieberman, Silva Hecimovic, Mikael Simons, Stefan F. Lichtenthaler, Michael Strupp, Susanne A. Schneider, Sabina Tahirovic

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Fibrillar Aβ triggers microglial proteome alterations and dysfunction in Alzheimer mouse models by Laura Sebastian Monasor, Stephan A Müller, Alessio Vittorio Colombo, Gaye Tanrioever, Jasmin König, Stefan Roth, Arthur Liesz, Anna Berghofer, Anke Piechotta, Matthias Prestel, Takashi Saito, Takaomi C Saido, Jochen Herms, Michael Willem, Christian Haass, Stefan F Lichtenthaler, Sabina Tahirovic

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Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model by Jasenka Rudan Njavro, Marija Vukicevic, Emma Fiorini, Lina Dinkel, Stephan A. Müller, Anna Berghofer, Chiara Bordier, Stanislav Kozlov, Annett Halle, Katrin Buschmann, Anja Capell, Camilla Giudici, Michael Willem, Regina Feederle, Stefan F. Lichtenthaler, Chiara Babolin, Paolo Montanari, Andrea Pfeifer, Marie Kosco-Vilbois, Sabina Tahirovic

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Experimental evidence for temporal uncoupling of brain Aβ deposition and neurodegenerative sequelae by Christine Rother, Ruth E. Uhlmann, Stephan A. Müller, Juliane Schelle, Angelos Skodras, Ulrike Obermüller, Lisa M. Häsler, Marius Lambert, Frank Baumann, Ying Xu, Carina Bergmann, Giulia Salvadori, Maarten Loos, Irena Brzak, Derya Shimshek, Ulf Neumann, Dominantly Inherited Alzheimer Network, Lary C. Walker, Stephanie A. Schultz, Jasmeer P. Chhatwal, Stephan A. Kaeser, Stefan F. Lichtenthaler, Matthias Staufenbiel, Mathias Jucker

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A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases by Alexander M. Bernhardt, Steffen Tiedt, Daniel Teupser, Martin Dichgans, Bernhard Meyer, Jens Gempt, Peer-Hendrik Kuhn, Mikael Simons, Carla Palleis, Endy Weidinger, Georg Nübling, Lesca Holdt, Lisa Hönikl, Christiane Gasperi, Pieter Giesbertz, Stephan A. Müller, Stephan Breimann, Stefan F. Lichtenthaler, Bernhard Kuster, Matthias Mann, Axel Imhof, Teresa Barth, Stefanie M. Hauck, Henrik Zetterberg, Markus Otto, Wilko Weichert, Bernhard Hemmer, Johannes Levin

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The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions by Mari Takalo, Heli Jeskanen, Taisia Rolova, Inka Kervinen, Marianna Hellén, Sami Heikkinen, Hennariikka Koivisto, Kimmo Jokivarsi, Stephan A. Müller, Esa-Mikko Koivumäki, Petra Mäkinen, Sini-Pauliina Juopperi, Roosa-Maria Willman, Rosa Sinisalo, Dorit Hoffmann, Henna Jäntti, Michael Peitz, Klaus Fließbach, Teemu Kuulasmaa, Teemu Natunen, Susanna Kemppainen, Pekka Poutiainen, Ville Leinonen, Tarja Malm, Henna Martiskainen, Alfredo Ramirez, Annakaisa Haapasalo, Stefan F. Lichtenthaler, Heikki Tanila, Christian Haass, Juha Rinne, Jari Koistinaho, Mikko Hiltunen

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Rational correction of pathogenic conformational defects in HTRA1 by Nathalie Beaufort, Linda Ingendahl, Melisa Merdanovic, Andree Schmidt, David Podlesainski, Tim Richter, Thorben Neumann, Michael Kuszner, Ingrid R. Vetter, Patricia Stege, Steven G. Burston, Anto Filipovic, Yasser B. Ruiz-Blanco, Kenny Bravo-Rodriguez, Joel Mieres-Perez, Christine Beuck, Stephan Uebel, Monika Zobawa, Jasmin Schillinger, Rainer Malik, Katalin Todorov-Völgyi, Juliana Rey, Annabell Roberti, Birte Hagemeier, Benedikt Wefers, Stephan A. Müller, Wolfgang Wurst, Elsa Sanchez-Garcia, Alexander Zimmermann, Xiao-Yu Hu, Tim Clausen, Robert Huber, Stefan F. Lichtenthaler, Carsten Schmuck, Michael Giese, Markus Kaiser, Michael Ehrmann, Martin Dichgans

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