Autoimmune lymphoproliferative immunodeficiencies (ALPID) in childhood: breakdown of immune homeostasis and immune dysregulation by Vasil Toskov, Stephan Ehl

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Cell Versus Cytokine – Directed Therapies for Hemophagocytic Lymphohistiocytosis (HLH) in Inborn Errors of Immunity by Oliver Wegehaupt, Oliver Wegehaupt, Katharina Wustrau, Kai Lehmberg, Stephan Ehl, Stephan Ehl

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Germline STAT3 gain-of-function mutations in primary immunodeficiency: Impact on the cellular and clinical phenotype by Laura Faletti, Stephan Ehl, Maximilian Heeg

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Tuberculosis-Associated HLH in an 8-Month-Old Infant: A Case Report and Review by Holger Hauch, Susanne Skrzypek, Wilhelm Woessmann, Kai Lehmberg, Stephan Ehl, Stephan Ehl, Carsten Speckmann, Carsten Speckmann, Emmanuel Schneck, Dieter Koerholz, Christian Jux, Christoph Neuhäuser

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SOCS1 deficiency—crossroads of autoimmunity and autoinflammation—two case reports by Kajetan Trojovsky, Maximilian Seidl, Florian Babor, Stephan Ehl, Stephan Ehl, Min Ae Lee-Kirsch, Michael Friedt, Hans-Juergen Laws, Nibras Naami, Prasad Thomas Oommen, Sujal Ghosh

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Adoptive T cell therapy cures mice from active hemophagocytic lymphohistiocytosis (HLH) by Kristoffer Weißert, Sandra Ammann, Tamara Kögl, Viviane Dettmer‐Monaco, Christoph Schell, Toni Cathomen, Stephan Ehl, Peter Aichele

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High Levels of IL-18 and IFN-γ in Chronically Inflamed Tissue in Chronic Granulomatous Disease by Virginia Meda Spaccamela, Virginia Meda Spaccamela, Rocio G. Valencia, Oleksandr Pastukhov, Oleksandr Pastukhov, Andrea Duppenthaler, Matthias S. Dettmer, Juliane Erb, Urs C. Steiner, Sven Hillinger, Carsten Speckmann, Carsten Speckmann, Stephan Ehl, Stephan Ehl, Janine Reichenbach, Janine Reichenbach, Janine Reichenbach, Janine Reichenbach, Ulrich Siler, Ulrich Siler

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Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7) by Doris Boeckelmann, Mira Wolter, Katharina Neubauer, Felix Sobotta, Antonia Lenz, Hannah Glonnegger, Barbara Käsmann-Kellner, Jasmin Mann, Stephan Ehl, Barbara Zieger

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Dysregulated PI3K Signaling in B Cells of CVID Patients by Ina Harder, Matthias Münchhalfen, Geoffroy Andrieux, Melanie Boerries, Bodo Grimbacher, Hermann Eibel, Maria Elena Maccari, Stephan Ehl, Jürgen Wienands, Julia Jellusova, Klaus Warnatz, Baerbel Keller

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Disease‐causing mutations in the XIAP BIR2 domain impair NOD2‐dependent immune signalling by Rune Busk Damgaard, Berthe Katrine Fiil, Carsten Speckmann, Monica Yabal, Udo zur Stadt, Simon Bekker‐Jensen, Philipp J. Jost, Stephan Ehl, Niels Mailand, Mads Gyrd‐Hansen

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Long-term robustness of a T-cell system emerging from somatic rescue of a genetic block in T-cell development by Patrick Kury, Marita Führer, Sebastian Fuchs, Myriam R. Lorenz, Orlando Bruno Giorgetti, Shahrzad Bakhtiar, Andreas P. Frei, Paul Fisch, Thomas Boehm, Klaus Schwarz, Carsten Speckmann, Stephan Ehl

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Case Report: Hemophagocytic Lymphohistiocytosis and Non-Tuberculous Mycobacteriosis Caused by a Novel GATA2 Variant by Thomas Mika, Deepak Vangala, Matthias Eckhardt, Paul La Rosée, Christoph Lange, Christoph Lange, Kai Lehmberg, Charlotte Wohlschläger, Saskia Biskup, Ilka Fuchs, Jasmin Mann, Stephan Ehl, Klaus Warnatz, Klaus Warnatz, Roland Schroers

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Griscelli Syndrome Type 2 Sine Albinism: Unraveling Differential RAB27A Effector Engagement by Yuta Ohishi, Sandra Ammann, Sandra Ammann, Vahid Ziaee, Vahid Ziaee, Katharina Strege, Miriam Groß, Carla Vazquez Amos, Mohammad Shahrooei, Parisa Ashournia, Anahita Razaghian, Gillian M. Griffiths, Stephan Ehl, Mitsunori Fukuda, Nima Parvaneh, Nima Parvaneh

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Germline biallelic PIK3CG mutations in a multifaceted immunodeficiency with immune dysregulation by Marini Thian, Birgit Hoeger, Anton Kamnev, Fiona Poyer, Sevgi Köstel Bal, Michael Caldera, Raúl Jiménez-Heredia, Jakob Huemer, Winfried F. Pickl, Miriam Groß, Stephan Ehl, Carrie L. Lucas, Jörg Menche, Caroline Hutter, Andishe Attarbaschi, Loïc Dupré, Kaan Boztug

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Immunodeficiency with susceptibility to lymphoma with complex genotype affecting energy metabolism (FBP1, ACAD9) and vesicle trafficking (RAB27A) by Nina Brauer, Yuto Maruta, Miriam Lisci, Miriam Lisci, Katharina Strege, Ilske Oschlies, Hikari Nakamura, Svea Böhm, Kai Lehmberg, Leon Brandhoff, Stephan Ehl, Nima Parvaneh, Wolfram Klapper, Mitsunori Fukuda, Gillian M. Griffiths, Hans Christian Hennies, Hans Christian Hennies, Tim Niehues, Sandra Ammann, Sandra Ammann

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Atypical familial hemophagocytic lymphohistiocytosis due to mutations in UNC13D and STXBP2 overlaps with primary immunodeficiency diseases by Jan Rohr, Karin Beutel, Andrea Maul-Pavicic, Thomas Vraetz, Jens Thiel, Klaus Warnatz, Ilka Bondzio, Ute Gross-Wieltsch, Michael Schündeln, Barbara Schütz, Wilhelm Woessmann, Andreas H. Groll, Brigitte Strahm, Julia Pagel, Carsten Speckmann, Gritta Janka, Gillian Griffiths, Klaus Schwarz, Udo zur Stadt, Stephan Ehl

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Evolution of disease activity and biomarkers on and off rapamycin in 28 patients with autoimmune lymphoproliferative syndrome by Christian Klemann, Myrian Esquivel, Aude Magerus-Chatinet, Myriam R. Lorenz, Ilka Fuchs, Nathalie Neveux, Martin Castelle, Jan Rohr, Claudia Bettoni da Cunha, Martin Ebinger, Robin Kobbe, Bernhard Kremens, Florian Kollert, Eleonora Gambineri, Kai Lehmberg, Markus G. Seidel, Kathrin Siepermann, Thomas Voelker, Volker Schuster, Sigune Goldacker, Klaus Schwarz, Carsten Speckmann, Capucine Picard, Alain Fischer, Frederic Rieux-Laucat, Stephan Ehl, Anne Rensing-Ehl, Benedicte Neven

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Immune profiling and functional analysis of NK and T cells in ataxia telangiectasia by Lea Graafen, Lea Graafen, Annekathrin Heinze, Annekathrin Heinze, Nawid Albinger, Nawid Albinger, Emilia Salzmann-Manrique, Franziska Ganß, Franziska Ganß, Franziska Ganß, Sabine Hünecke, Claudia Cappel, Sandra Wölke, Sandra Wölke, Helena Donath, Helena Donath, Jordis Trischler, Jordis Trischler, Till-Martin Theilen, Christine Heller, Christoph Königs, Stephan Ehl, Peter Bader, Thomas Klingebiel, Jan-Henning Klusmann, Jan-Henning Klusmann, Stefan Zielen, Stefan Zielen, Ralf Schubert, Ralf Schubert, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich, Evelyn Ullrich

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The syndrome of hemophagocytic lymphohistiocytosis in primary immunodeficiencies: implications for differential diagnosis and pathogenesis by Sebastian FN Bode, Sandra Ammann, Waleed Al-Herz, Mihaela Bataneant, Christopher C Dvorak, Stephan Gehring, Andrew Gennery, Kimberly C Gilmour, Luis I Gonzalez-Granado, Ute Groß-Wieltsch, Marianne Ifversen, Jenny Lingman-Framme, Susanne Matthes-Martin, Rolf Mesters, Isabelle Meyts, Joris M van Montfrans, Jana Pachlopnik Schmid, Sung-Yun Pai, Pere Soler-Palacin, Uta Schuermann, Volker Schuster, Markus G. Seidel, Carsten Speckmann, Polina Stepensky, Karl-Walter Sykora, Bianca Tesi, Thomas Vraetz, Catherine Waruiru, Yenan T. Bryceson, Despina Moshous, Kai Lehmberg, Michael B Jordan, Stephan Ehl

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Sequential decisions on FAS sequencing guided by biomarkers in patients with lymphoproliferation and autoimmune cytopenia by Anne Rensing-Ehl, Ales Janda, Myriam R. Lorenz, Beryl P. Gladstone, Ilka Fuchs, Mario Abinun, Michael Albert, Karina Butler, Andrew Cant, Anna-Maria Cseh, Martin Ebinger, Sigune Goldacker, Sophie Hambleton, Holger Hebart, Leonora Houet, Karim Kentouche, Ingrid Kühnle, Kai Lehmberg, Ester Mejstrikova, Charlotte Niemeyer, Milen Minkov, Olaf Neth, Gregor Dückers, Stephan Owens, Joachim Rösler, Freimut H. Schilling, Volker Schuster, Markus G. Seidel, Petr Smisek, Martina Sukova, Peter Svec, Thomas Wiesel, Benjamin Gathmann, Klaus Schwarz, Werner Vach, Stephan Ehl, Carsten Speckmann

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