PET Imaging of Synaptic Density: Challenges and Opportunities of Synaptic Vesicle Glycoprotein 2A PET in Small Animal Imaging af Takuya Toyonaga, Arman Fesharaki-Zadeh, Arman Fesharaki-Zadeh, Stephen M. Strittmatter, Stephen M. Strittmatter, Richard E. Carson, Zhengxin Cai

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Gene-environment interaction promotes Alzheimer's risk as revealed by synergy of repeated mild traumatic brain injury and mouse App knock-in af Marius Chiasseu, Arman Fesharaki-Zadeh, Takashi Saito, Takaomi C. Saido, Stephen M. Strittmatter

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Lysosomal TMEM106B interacts with galactosylceramidase to regulate myelin lipid metabolism af Hideyuki Takahashi, Azucena Perez-Canamas, Chris W. Lee, Hongping Ye, Xianlin Han, Stephen M. Strittmatter

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Identification of Intrinsic Axon Growth Modulators for Intact CNS Neurons after Injury af Kathren L. Fink, Francesc López-Giráldez, In-Jung Kim, Stephen M. Strittmatter, William B.J. Cafferty

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Inhibiting poly(ADP-ribosylation) improves axon regeneration af Alexandra B Byrne, Rebecca D McWhirter, Yuichi Sekine, Stephen M Strittmatter, David M Miller III, Marc Hammarlund

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Neuronal transcriptome, tau and synapse loss in Alzheimer’s knock-in mice require prion protein af Austin Stoner, Li Fu, LaShae Nicholson, Chao Zheng, Takuya Toyonaga, Joshua Spurrier, Will Laird, Zhengxin Cai, Stephen M. Strittmatter

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Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase af Hideyuki Takahashi, Sanaea Bhagwagar, Sarah H. Nies, Hongping Ye, Xianlin Han, Marius T. Chiasseu, Guilin Wang, Ian R. Mackenzie, Stephen M. Strittmatter

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Fyn kinase inhibition reduces protein aggregation, increases synapse density and improves memory in transgenic and traumatic Tauopathy af Si Jie Tang, Arman Fesharaki-Zadeh, Hideyuki Takahashi, Sarah Helena Nies, Levi M. Smith, Anin Luo, Annabel Chyung, Marius Chiasseu, Stephen M. Strittmatter

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Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy af A. Harrison Brody, Sarah Helena Nies, Fulin Guan, Levi M. Smith, Bandhan Mukherjee, Santiago A. Salazar, Suho Lee, Tu Kiet T. Lam, Stephen M. Strittmatter

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Correction: Alzheimer risk gene product Pyk2 suppresses tau phosphorylation and phenotypic effects of tauopathy af A. Harrison Brody, Sarah Helena Nies, Fulin Guan, Levi M. Smith, Bandhan Mukherjee, Santiago A. Salazar, Suho Lee, Tu Kiet T. Lam, Stephen M. Strittmatter

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Human neuroepithelial stem cell regional specificity enables spinal cord repair through a relay circuit af Maria Teresa Dell’Anno, Xingxing Wang, Marco Onorati, Mingfeng Li, Francesca Talpo, Yuichi Sekine, Shaojie Ma, Fuchen Liu, William B. J. Cafferty, Nenad Sestan, Stephen M. Strittmatter

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Decreased synaptic vesicle glycoprotein 2A binding in a rodent model of familial Alzheimer's disease detected by [18F]SDM-16 af Chao Zheng, Takuya Toyonaga, Baosheng Chen, LaShae Nicholson, William Mennie, Michael Liu, Joshua Spurrier, Kristin Deluca, Stephen M. Strittmatter, Richard E. Carson, Yiyun Huang, Zhengxin Cai

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Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer’s Mouse Phenotypes af Laura T. Haas, Santiago V. Salazar, Levi M. Smith, Helen R. Zhao, Timothy O. Cox, Charlotte S. Herber, Andrew P. Degnan, Anand Balakrishnan, John E. Macor, Charles F. Albright, Stephen M. Strittmatter

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NogoA-expressing astrocytes limit peripheral macrophage infiltration after ischemic brain injury in primates af Anthony G. Boghdadi, Joshua Spurrier, Leon Teo, Mingfeng Li, Mario Skarica, Benjamin Cao, William C. Kwan, Tobias D. Merson, Susan K. Nilsson, Nenad Sestan, Stephen M. Strittmatter, James A. Bourne

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Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions af Karen Perez de Arce, Adema Ribic, Dhrubajyoti Chowdhury, Katherine Watters, Garth J. Thompson, Basavaraju G. Sanganahalli, Elizabeth T. C. Lippard, Astrid Rohlmann, Stephen M. Strittmatter, Markus Missler, Fahmeed Hyder, Thomas Biederer

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TMEM106B Puncta Is Increased in Multiple Sclerosis Plaques, and Reduced Protein in Mice Results in Delayed Lipid Clearance Following CNS Injury af Bridget Shafit-Zagardo, Simone Sidoli, James E. Goldman, Juwen C. DuBois, John R. Corboy, Stephen M. Strittmatter, Hillary Guzik, Ukuemi Edema, Anita G. Arackal, Yair M. Botbol, Emilio Merheb, Rashed M. Nagra, Sarah Graff

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B-cells expressing NgR1 and NgR3 are localized to EAE-induced inflammatory infiltrates and are stimulated by BAFF af Maha M. Bakhuraysah, Paschalis Theotokis, Jae Young Lee, Amani A. Alrehaili, Pei-Mun Aui, William A. Figgett, Michael F. Azari, John-Paul Abou-Afech, Fabienne Mackay, Christopher Siatskas, Frank Alderuccio, Stephen M. Strittmatter, Nikolaos Grigoriadis, Steven Petratos

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PET imaging of mGluR5 in Alzheimer’s disease af Adam P. Mecca, Julia W. McDonald, Hannah R. Michalak, Tyler A. Godek, Joanna E. Harris, Erika A. Pugh, Emily C. Kemp, Ming-Kai Chen, Arash Salardini, Nabeel B. Nabulsi, Keunpoong Lim, Yiyun Huang, Richard E. Carson, Stephen M. Strittmatter, Christopher H. van Dyck

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Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia af Marco Onorati, Zhen Li, Fuchen Liu, André M.M. Sousa, Naoki Nakagawa, Mingfeng Li, Maria Teresa Dell’Anno, Forrest O. Gulden, Sirisha Pochareddy, Andrew T.N. Tebbenkamp, Wenqi Han, Mihovil Pletikos, Tianliuyun Gao, Ying Zhu, Candace Bichsel, Luis Varela, Klara Szigeti-Buck, Steven Lisgo, Yalan Zhang, Anze Testen, Xiao-Bing Gao, Jernej Mlakar, Mara Popovic, Marie Flamand, Stephen M. Strittmatter, Leonard K. Kaczmarek, E.S. Anton, Tamas L. Horvath, Brett D. Lindenbach, Nenad Sestan

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