The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER. by Belinda S Hall, Kirsti Hill, Michael McKenna, Joy Ogbechi, Stephen High, Anne E Willis, Rachel E Simmonds

Get full text

Proteomics Identifies Substrates and a Novel Component in hSnd2-Dependent ER Protein Targeting by Andrea Tirincsi, Sarah O’Keefe, Duy Nguyen, Mark Sicking, Johanna Dudek, Friedrich Förster, Martin Jung, Drazena Hadzibeganovic, Volkhard Helms, Stephen High, Richard Zimmermann, Sven Lang

Get full text

Synthesis, Biological Evaluation and Docking Studies of Ring-Opened Analogues of Ipomoeassin F by Sarah O’Keefe, Pratiti Bhadra, Kwabena B. Duah, Guanghui Zong, Levise Tenay, Lauren Andrews, Hayden Schneider, Ashley Anderson, Zhijian Hu, Hazim S. Aljewari, Belinda S. Hall, Rachel E. Simmonds, Volkhard Helms, Stephen High, Wei Q. Shi

Get full text

Endocytic recycling is central to circadian collagen fibrillogenesis and disrupted in fibrosis by Joan Chang, Adam Pickard, Jeremy A Herrera, Sarah O'Keefe, Richa Garva, Matthew Hartshorn, Anna Hoyle, Lewis Dingle, John Knox, Thomas A Jowitt, Madeleine Coy, Jason Wong, Adam Reid, Yinhui Lu, Cédric Zeltz, Rajamiyer V Venkateswaran, Patrick T Caswell, Stephen High, Donald Gullberg, Karl E Kadler

Get full text

The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity by Hazel Stewart, Yongxu Lu, Sarah O’Keefe, Anusha Valpadashi, Luis Daniel Cruz-Zaragoza, Hendrik A. Michel, Samantha K. Nguyen, George W. Carnell, Nina Lukhovitskaya, Rachel Milligan, Yasmin Adewusi, Irwin Jungreis, Valeria Lulla, David A. Matthews, Stephen High, Peter Rehling, Edward Emmott, Jonathan L. Heeney, Andrew D. Davidson, James R. Edgar, Geoffrey L. Smith, Andrew E. Firth

Get full text