Stephen O'Rahilly

Stephen O'Rahilly '''Sir Stephen Patrick O'Rahilly''' (born 1 April 1958) is an Irish-British physician and scientist known for his research into the molecular pathogenesis of human obesity, insulin resistance and related metabolic and endocrine disorders. Provided by Wikipedia
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  1. 1
    AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles

    AMPK is required for exercise to enhance insulin sensitivity in skeletal muscles by Jørgen Jensen, Stephen O'Rahilly

    Published 2017-04-01
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  2. 2
    Development, factor structure and application of the Dog Obesity Risk and Appetite (DORA) questionnaire

    Development, factor structure and application of the Dog Obesity Risk and Appetite (DORA) questionnaire by Eleanor Raffan, Stephen P. Smith, Stephen O’Rahilly, Jane Wardle

    Published 2015-09-01
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  3. 3
    The McKittrick–Wheelock syndrome: a rare cause of curable diabetes

    The McKittrick–Wheelock syndrome: a rare cause of curable diabetes by Benjamin G Challis, Chung Thong Lim, Alison Cluroe, Ewen Cameron, Stephen O’Rahilly

    Published 2016-05-01
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  4. 4
    Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity.

    Genetic variance in the spinocerebellar ataxia type 2 (ATXN2) gene in children with severe early onset obesity. by Karla P Figueroa, Sadaf Farooqi, Kristopher Harrup, Johnathan Frank, Stephen O'Rahilly, Stefan M Pulst

    Published 2009-12-01
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  5. 5
    Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

    Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis by Md. Mesbah Uddin Talukder, M.F. Michelle Sim, Stephen O'Rahilly, J. Michael Edwardson, Justin J. Rochford

    Published 2015-03-01
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  6. 6
    Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats.

    Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. by Yi-Chun Loraine Tung, Eduard Ayuso, Xiaoye Shan, Fatima Bosch, Stephen O'Rahilly, Anthony P Coll, Giles S H Yeo

    Published 2010-01-01
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  7. 7
    The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15

    The gastrointestinal tract is a major source of the acute metformin-stimulated rise in GDF15 by John W. R. Kincaid, Debra Rimmington, John A. Tadross, Irene Cimino, Ilona Zvetkova, Arthur Kaser, Paul Richards, Satish Patel, Stephen O’Rahilly, Anthony P. Coll

    Published 2024-01-01
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  8. 8
    Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action.

    Candidate gene association study in type 2 diabetes indicates a role for genes involved in beta-cell function as well as insulin action. by Inês Barroso, Jian'an Luan, Rita P S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, D Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham

    Published 2003-10-01
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  9. 9
    Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels

    Sequence variants in the melatonin-related receptor gene (GPR50) associate with circulating triglyceride and HDL levels by Sumit Bhattacharyya, Jian'an Luan, Benjamin Challis, Julia Keogh, Carl Montague, John Brennand, John Morten, Sarah Lowenbeim, Suzanne Jenkins, I. Sadaf Farooqi, Nicholas J. Wareham, Stephen O'Rahilly

    Published 2006-04-01
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  10. 10
    In PLoS Biology, volume 1, issue 1:: Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action.

    In PLoS Biology, volume 1, issue 1:: Candidate Gene Association Study in Type 2 Diabetes Indicates a Role for Genes Involved in β-Cell Function as Well as Insulin Action. by Inês Barroso, Jian'an Luan, Rita P. S Middelberg, Anne-Helen Harding, Paul W Franks, Rupert W Jakes, David Clayton, Alan J Schafer, Stephen O'Rahilly, Nicholas J Wareham

    Published 2003-12-01
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  11. 11
    FTO is necessary for the induction of leptin resistance by high-fat feeding

    FTO is necessary for the induction of leptin resistance by high-fat feeding by Y.C. Loraine Tung, Pawan Gulati, Che-Hsiung Liu, Debra Rimmington, Rowena Dennis, Marcella Ma, Vladimir Saudek, Stephen O'Rahilly, Anthony P. Coll, Giles S.H. Yeo

    Published 2015-04-01
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  12. 12
    Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion

    Phenotypic characterization of Adig null mice suggests roles for adipogenin in the regulation of fat mass accrual and leptin secretion by Anna Alvarez-Guaita, Satish Patel, Koini Lim, Afreen Haider, Liang Dong, Olivia J. Conway, Marcella K.L. Ma, Davide Chiarugi, Vladimir Saudek, Stephen O’Rahilly, David B. Savage

    Published 2021-03-01
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  13. 13
    Divergent effects of central melanocortin signalling on fat and sucrose preference in humans

    Divergent effects of central melanocortin signalling on fat and sucrose preference in humans by Agatha A. van der Klaauw, Julia M. Keogh, Elana Henning, Cheryl Stephenson, Sarah Kelway, Victoria M. Trowse, Naresh Subramanian, Stephen O’Rahilly, Paul C. Fletcher, I. Sadaf Farooqi

    Published 2016-10-01
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  14. 14
    Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis

    Quantitative mass spectrometry for human melanocortin peptides in vitro and in vivo suggests prominent roles for β-MSH and desacetyl α-MSH in energy homeostasis by Peter Kirwan, Richard G. Kay, Bas Brouwers, Vicente Herranz-Pérez, Magdalena Jura, Pierre Larraufie, Julie Jerber, Jason Pembroke, Theresa Bartels, Anne White, Fiona M. Gribble, Frank Reimann, I. Sadaf Farooqi, Stephen O'Rahilly, Florian T. Merkle

    Published 2018-11-01
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  15. 15
    Genetic architecture of human thinness compared to severe obesity.

    Genetic architecture of human thinness compared to severe obesity. by Fernando Riveros-McKay, Vanisha Mistry, Rebecca Bounds, Audrey Hendricks, Julia M Keogh, Hannah Thomas, Elana Henning, Laura J Corbin, Understanding Society Scientific Group, Stephen O'Rahilly, Eleftheria Zeggini, Eleanor Wheeler, Inês Barroso, I Sadaf Farooqi

    Published 2019-01-01
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  16. 16
    Adult onset global loss of the fto gene alters body composition and metabolism in the mouse.

    Adult onset global loss of the fto gene alters body composition and metabolism in the mouse. by Fiona McMurray, Chris D Church, Rachel Larder, George Nicholson, Sara Wells, Lydia Teboul, Y C Loraine Tung, Debra Rimmington, Fatima Bosch, Veronica Jimenez, Giles S H Yeo, Stephen O'Rahilly, Frances M Ashcroft, Anthony P Coll, Roger D Cox

    Published 2013-01-01
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  17. 17
    A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

    A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion by Jake P Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Sam Virtue, Stephen O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage

    Published 2023-02-01
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  18. 18
    Loss of Mfn1 but not Mfn2 enhances adipogenesis.

    Loss of Mfn1 but not Mfn2 enhances adipogenesis. by Jake P Mann, Luis Carlos Tábara, Satish Patel, Pushpa Pushpa, Anna Alvarez-Guaita, Liang Dong, Afreen Haider, Koini Lim, Panna Tandon, Fabio Scurria, James E N Minchin, Stephen O'Rahilly S, Daniel J Fazakerley, Julien Prudent, Robert K Semple, David B Savage

    Published 2024-01-01
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  19. 19
    Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure

    Truncation of Pik3r1 causes severe insulin resistance uncoupled from obesity and dyslipidaemia by increased energy expenditure by Albert Kwok, Ilona Zvetkova, Sam Virtue, Ineke Luijten, Isabel Huang-Doran, Patsy Tomlinson, David A. Bulger, James West, Steven Murfitt, Julian Griffin, Rafeah Alam, Daniel Hart, Rachel Knox, Peter Voshol, Antonio Vidal-Puig, Jørgen Jensen, Stephen O'Rahilly, Robert K. Semple

    Published 2020-10-01
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  20. 20
    Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice

    Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice by Satish Patel, Afreen Haider, Anna Alvarez-Guaita, Guillaume Bidault, Julia Sarah El-Sayed Moustafa, Esther Guiu-Jurado, John A. Tadross, James Warner, James Harrison, Samuel Virtue, Fabio Scurria, Ilona Zvetkova, Matthias Blüher, Kerrin S. Small, Stephen O’Rahilly, David B. Savage

    Published 2022-11-01
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