A dynamic landscape for antibody binding modulates antibody-mediated neutralization of West Nile virus. by Kimberly A Dowd, Christiane A Jost, Anna P Durbin, Stephen S Whitehead, Theodore C Pierson

Get full text

Dual miRNA targeting restricts host range and attenuates neurovirulence of flaviviruses. by Konstantin A Tsetsarkin, Guangping Liu, Heather Kenney, Jose Bustos-Arriaga, Christopher T Hanson, Stephen S Whitehead, Alexander G Pletnev

Get full text

Primary vaccination with low dose live dengue 1 virus generates a proinflammatory, multifunctional T cell response in humans. by Janet C Lindow, Nathan Borochoff-Porte, Anna P Durbin, Stephen S Whitehead, Kelly A Fimlaid, Janice Y Bunn, Beth D Kirkpatrick

Get full text

A Full-Length Infectious cDNA Clone of Zika Virus from the 2015 Epidemic in Brazil as a Genetic Platform for Studies of Virus-Host Interactions and Vaccine Development by Konstantin A. Tsetsarkin, Heather Kenney, Rubing Chen, Guangping Liu, Hasmik Manukyan, Stephen S. Whitehead, Majid Laassri, Konstantin Chumakov, Alexander G. Pletnev

Get full text

The innate immune response following multivalent dengue vaccination and implications for protection against dengue challenge by Ruixue Hou, Lewis E. Tomalin, Jessica Pintado Silva, Seunghee Kim-Schulze, Stephen S. Whitehead, Ana Fernandez-Sesma, Anna P. Durbin, Mayte Suárez-Fariñas

Get full text

Antigenic Variation of the Dengue Virus 2 Genotypes Impacts the Neutralization Activity of Human Antibodies in Vaccinees by David R. Martinez, Boyd Yount, Usha Nivarthi, Jennifer E. Munt, Matthew J. Delacruz, Stephen S. Whitehead, Anna P. Durbin, Aravinda M. de Silva, Ralph S. Baric

Get full text

Lethal Zika Virus Disease Models in Young and Older Interferon α/β Receptor Knock Out Mice by Andrea Marzi, Jackson Emanuel, Julie Callison, Kristin L. McNally, Nicolette Arndt, Spencer Chadinha, Cynthia Martellaro, Rebecca Rosenke, Dana P. Scott, David Safronetz, Stephen S. Whitehead, Sonja M. Best, Heinz Feldmann

Get full text

Cross-reactive antibodies facilitate innate sensing of dengue and Zika viruses by Laura K. Aisenberg, Kimberly E. Rousseau, Katherine Cascino, Guido Massaccesi, William H. Aisenberg, Wensheng Luo, Kar Muthumani, David B. Weiner, Stephen S. Whitehead, Michael A. Chattergoon, Anna P. Durbin, Andrea L. Cox

Get full text

Neutralizing antibodies from prior exposure to dengue virus negatively correlate with viremia on re-infection by Anbalagan Anantharaj, Tanvi Agrawal, Pooja Kumari Shashi, Alok Tripathi, Parveen Kumar, Imran Khan, Madhu Pareek, Balwant Singh, Chitra Pattabiraman, Saurabh Kumar, Rajesh Pandey, Anmol Chandele, Rakesh Lodha, Stephen S. Whitehead, Guruprasad R. Medigeshi

Get full text

Viridot: An automated virus plaque (immunofocus) counter for the measurement of serological neutralizing responses with application to dengue virus. by Leah C Katzelnick, Ana Coello Escoto, Benjamin D McElvany, Christian Chávez, Henrik Salje, Wensheng Luo, Isabel Rodriguez-Barraquer, Richard Jarman, Anna P Durbin, Sean A Diehl, Derek J Smith, Stephen S Whitehead, Derek A T Cummings

Get full text

Longitudinal analysis of acute and convalescent B cell responses in a human primary dengue serotype 2 infection modelResearch in context by Usha K. Nivarthi, Huy A. Tu, Matthew J. Delacruz, Jesica Swanstrom, Bhumi Patel, Anna P. Durbin, Stephen S. Whitehead, Kristen K. Pierce, Beth D. Kirkpatrick, Ralph S. Baric, Ngan Nguyen, Daniel E. Emerling, Aravinda M. de Silva, Sean A. Diehl

Get full text

Corticosteroids for dengue - why don't they work? by Thi Hanh Tien Nguyen, Than Ha Quyen Nguyen, Tuan Trung Vu, Jeremy Farrar, Truong Long Hoang, Thi Hoai Tam Dong, Van Ngoc Tran, Khanh Lam Phung, Marcel Wolbers, Stephen S Whitehead, Martin L Hibberd, Bridget Wills, Cameron P Simmons

Get full text

Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance by Carol L. Vinton, Samuel J. Magaziner, Kimberly A. Dowd, Shelly J. Robertson, Emerito Amaro-Carambot, Erik P. Karmele, Alexandra M. Ortiz, Carly E. Starke, Joseph C. Mudd, Stephen S. Whitehead, Sonja M. Best, Theodore C. Pierson, Heather D. Hickman, Jason M. Brenchley

Get full text

Clinical and virological features of Dengue in Vietnamese infants. by Tran Nguyen Bich Chau, Katherine L Anders, Le Bich Lien, Nguyen Thanh Hung, Lu Thi Minh Hieu, Nguyen Minh Tuan, Tran Thi Thuy, Le Thi Phuong, Nguyen Thi Hong Tham, Mai Ngoc Lanh, Jeremy J Farrar, Stephen S Whitehead, Cameron P Simmons

Get full text

Phase 1 trial to model primary, secondary, and tertiary dengue using a monovalent vaccine by Camila D. Odio, Kelsey E. Lowman, Melissa Law, Rosemary A. Aogo, Sally Hunsberger, Brad J. Wood, Michael Kassin, Elliot Levy, Viviane Callier, Saba Firdous, Chloe M. Hasund, Charlie Voirin, Robbie Kattappuram, Christina Yek, Jessica Manning, Anna Durbin, Stephen S. Whitehead, Leah C. Katzelnick

Get full text

Current vector research challenges in the greater Mekong subregion for dengue, Malaria, and Other Vector-Borne Diseases: A report from a multisectoral workshop March 2019. by Rebecca C Christofferson, Daniel M Parker, Hans J Overgaard, Jeffrey Hii, Gregor Devine, Bruce A Wilcox, Vu Sinh Nam, Sazaly Abubakar, Sebastien Boyer, Kobporn Boonnak, Stephen S Whitehead, Rekol Huy, Leang Rithea, Tho Sochantha, Thomas E Wellems, Jesus G Valenzuela, Jessica E Manning

Get full text

Immunotranscriptomic profiling the acute and clearance phases of a human challenge dengue virus serotype 2 infection model by John P. Hanley, Huy A. Tu, Julie A. Dragon, Dorothy M. Dickson, Roxana del Rio-Guerra, Scott W. Tighe, Korin M. Eckstrom, Nicholas Selig, Samuel V. Scarpino, Stephen S. Whitehead, Anna P. Durbin, Kristen K. Pierce, Beth D. Kirkpatrick, Donna M. Rizzo, Seth Frietze, Sean A. Diehl

Get full text

In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination. by Stephen S Whitehead, Anna P Durbin, Kristen K Pierce, Dan Elwood, Benjamin D McElvany, Ellen A Fraser, Marya P Carmolli, Cecilia M Tibery, Noreen A Hynes, Matthew Jo, Janece M Lovchik, Catherine J Larsson, Elena A Doty, Dorothy M Dickson, Catherine J Luke, Kanta Subbarao, Sean A Diehl, Beth D Kirkpatrick

Get full text

Rapid Induction and Maintenance of Virus-Specific CD8+ TEMRA and CD4+ TEM Cells Following Protective Vaccination Against Dengue Virus Challenge in Humans by Nancy Graham, Nancy Graham, Phil Eisenhauer, Phil Eisenhauer, Sean A. Diehl, Sean A. Diehl, Kristen K. Pierce, Kristen K. Pierce, Stephen S. Whitehead, Anna P. Durbin, Beth D. Kirkpatrick, Beth D. Kirkpatrick, Beth D. Kirkpatrick, Alessandro Sette, Alessandro Sette, Daniela Weiskopf, Jonathan E. Boyson, Jason W. Botten, Jason W. Botten, Jason W. Botten

Get full text

Beneath the surface: Amino acid variation underlying two decades of dengue virus antigenic dynamics in Bangkok, Thailand. by Angkana T Huang, Henrik Salje, Ana Coello Escoto, Nayeem Chowdhury, Christian Chávez, Bernardo Garcia-Carreras, Wiriya Rutvisuttinunt, Irina Maljkovic Berry, Gregory D Gromowski, Lin Wang, Chonticha Klungthong, Butsaya Thaisomboonsuk, Ananda Nisalak, Luke M Trimmer-Smith, Isabel Rodriguez-Barraquer, Damon W Ellison, Anthony R Jones, Stefan Fernandez, Stephen J Thomas, Derek J Smith, Richard Jarman, Stephen S Whitehead, Derek A T Cummings, Leah C Katzelnick

Get full text