Towards an encyclopaedia of mammalian gene function: the International Mouse Phenotyping Consortium by Steve D. M. Brown, Mark W. Moore

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Understanding mammalian genetic systems: the challenge of phenotyping in the mouse. by Steve D M Brown, John M Hancock, Hilary Gates

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The Jeff Mouse Mutant Model for Chronic Otitis Media Manifests Gain-of-Function as Well as Loss-of-Function Effects by Oana Kubinyecz, Pratik P. Vikhe, Thomas Purnell, Steve D. M. Brown, Hilda Tateossian

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Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung by Hilda Tateossian, Susan Morse, Michelle M. Simon, Charlotte H. Dean, Steve D. M. Brown

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Mutation in Fbxo11 Leads to Altered Immune Cell Content in Jeff Mouse Model of Otitis Media by Pratik P. Vikhe, Hilda Tateossian, Gurpreet Bharj, Steve D.M. Brown, Derek W. Hood

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Multivariate phenotype analysis enables genome-wide inference of mammalian gene function. by George Nicholson, Hugh Morgan, Habib Ganjgahi, Steve D M Brown, Ann-Marie Mallon, Chris Holmes

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Gelsolin plays a role in the actin polymerization complex of hair cell stereocilia. by Philomena Mburu, María Rosario Romero, Helen Hilton, Andrew Parker, Stuart Townsend, Yoshiaki Kikkawa, Steve D M Brown

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The actin-binding proteins eps8 and gelsolin have complementary roles in regulating the growth and stability of mechanosensory hair bundles of mammalian cochlear outer hair cells. by Jennifer Olt, Philomena Mburu, Stuart L Johnson, Andy Parker, Stephanie Kuhn, Mike Bowl, Walter Marcotti, Steve D M Brown

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Loss of the homeostatic protein BPIFA1, leads to exacerbation of otitis media severity in the Junbo mouse model by Apoorva Mulay, Derek W. Hood, Debbie Williams, Catherine Russell, Steve D. M. Brown, Lynne Bingle, Michael Cheeseman, Colin D. Bingle

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Regulatory variation at glypican-3 underlies a major growth QTL in mice. by Fiona Oliver, Julian K Christians, Xiaojun Liu, Susan Rhind, Vinesh Verma, Claire Davison, Steve D M Brown, Paul Denny, Peter D Keightley

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A new model for non-typeable Haemophilus influenzae middle ear infection in the Junbo mutant mouse by Derek Hood, Richard Moxon, Tom Purnell, Caroline Richter, Debbie Williams, Ali Azar, Michael Crompton, Sara Wells, Martin Fray, Steve D. M. Brown, Michael T. Cheeseman

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The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells by Andrew Parker, Sally H. Cross, Ian J. Jackson, Rachel Hardisty-Hughes, Susan Morse, George Nicholson, Emma Coghill, Michael R. Bowl, Steve D. M. Brown

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Reducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice. by Silvia Corrochano, Maurizio Renna, Georgina Osborne, Sarah Carter, Michelle Stewart, Joel May, Gillian P Bates, Steve D M Brown, David C Rubinsztein, Abraham Acevedo-Arozena

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A holistic view of mouse enhancer architectures reveals analogous pleiotropic effects and correlation with human disease by Siddharth Sethi, Ilya E. Vorontsov, Ivan V. Kulakovskiy, Simon Greenaway, John Williams, Vsevolod J. Makeev, Steve D. M. Brown, Michelle M. Simon, Ann-Marie Mallon

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An in vitro model of murine middle ear epithelium by Apoorva Mulay, Khondoker M. Akram, Debbie Williams, Hannah Armes, Catherine Russell, Derek Hood, Stuart Armstrong, James P. Stewart, Steve D. M. Brown, Lynne Bingle, Colin D. Bingle

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Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing. by Sherylanne Newton, Fanbo Kong, Adam J Carlton, Carlos Aguilar, Andrew Parker, Gemma F Codner, Lydia Teboul, Sara Wells, Steve D M Brown, Walter Marcotti, Michael R Bowl

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N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models. by Christopher T Esapa, Fadil M Hannan, Valerie N Babinsky, Paul Potter, Gethin P Thomas, Peter I Croucher, Matthew A Brown, Steve D M Brown, Roger D Cox, Rajesh V Thakker

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A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation. by Sian E Piret, Christopher T Esapa, Caroline M Gorvin, Rosie Head, Nellie Y Loh, Olivier Devuyst, Gethin Thomas, Steve D M Brown, Matthew Brown, Peter Croucher, Roger Cox, Rajesh V Thakker

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AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness by Jing-Yi Jeng, Adam J. Carlton, Richard J. Goodyear, Colbie Chinowsky, Federico Ceriani, Stuart L. Johnson, Tsung-Chang Sung, Yelena Dayn, Guy P. Richardson, Michael R. Bowl, Steve D.M. Brown, Uri Manor, Walter Marcotti

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CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells by Arnaud P. J. Giese, Yi-Quan Tang, Ghanshyam P. Sinha, Michael R. Bowl, Adam C. Goldring, Andrew Parker, Mary J. Freeman, Steve D. M. Brown, Saima Riazuddin, Robert Fettiplace, William R. Schafer, Gregory I. Frolenkov, Zubair M. Ahmed

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