CDK9 and H2B monoubiquitination: a well-choreographed dance. by Steven A Johnsen

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Epigenetic Targeting of Aberrant Transcriptional Modulation in Pancreatic Cancer by Feda H. Hamdan, Steven A. Johnsen

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Perturbing Enhancer Activity in Cancer Therapy by Feda H. Hamdan, Steven A. Johnsen

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Store-Operated Calcium Entry: Shaping the Transcriptional and Epigenetic Landscape in Pancreatic Cancer by Ana P. Kutschat, Steven A. Johnsen, Feda H. Hamdan

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SAGA-Dependent Histone H2Bub1 Deubiquitination Is Essential for Cellular Ubiquitin Balance during Embryonic Development by Farrah El-Saafin, Didier Devys, Steven A. Johnsen, Stéphane D. Vincent, László Tora

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USP22 Suppresses <i>SPARC</i> Expression in Acute Colitis and Inflammation-Associated Colorectal Cancer by Robyn Laura Kosinsky, Dominik Saul, Christoph Ammer-Herrmenau, William A. Faubion, Albrecht Neesse, Steven A. Johnsen

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Epigenome Mapping Identifies Tumor-Specific Gene Expression in Primary Rectal Cancer by Hannah Flebbe, Feda H. Hamdan, Vijayalakshmi Kari, Julia Kitz, Jochen Gaedcke, B. Michael Ghadimi, Steven A. Johnsen, Marian Grade

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USP22 supports the aggressive behavior of basal-like breast cancer by stimulating cellular respiration by Evangelos Prokakis, Husam Bamahmoud, Shaishavi Jansari, Lena Fritsche, Alexander Dietz, Angela Boshnakovska, Peter Rehling, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz

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RNF40 epigenetically modulates glycolysis to support the aggressiveness of basal-like breast cancer by Evangelos Prokakis, Shaishavi Jansari, Angela Boshnakovska, Maria Wiese, Kathrin Kusch, Christof Kramm, Christian Dullin, Peter Rehling, Markus Glatzel, Klaus Pantel, Harriet Wikman, Steven A. Johnsen, Julia Gallwas, Florian Wegwitz

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Bromodomain Protein BRD4 Is Required for Estrogen Receptor-Dependent Enhancer Activation and Gene Transcription by Sankari Nagarajan, Tareq Hossan, Malik Alawi, Zeynab Najafova, Daniela Indenbirken, Upasana Bedi, Hanna Taipaleenmäki, Isabel Ben-Batalla, Marina Scheller, Sonja Loges, Stefan Knapp, Eric Hesse, Cheng-Ming Chiang, Adam Grundhoff, Steven A. Johnsen

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NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell ReprogrammingSummary by Zhe Zhang, Xin Wang, Feda H. Hamdan, Anna Likhobabina, Shilpa Patil, Lena Aperdannier, Madhobi Sen, Jacobe Traub, Albrecht Neesse, André Fischer, Argyris Papantonis, Shiv K. Singh, Volker Ellenrieder, Steven A. Johnsen, Elisabeth Hessmann

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NOTCH Activation via gp130/STAT3 Signaling Confers Resistance to Chemoradiotherapy by Kristin Koerdel, Melanie Spitzner, Thomas Meyer, Niklas Engels, Florian Krause, Jochen Gaedcke, Lena-Christin Conradi, Martin Haubrock, Tim Beißbarth, Andreas Leha, Steven A. Johnsen, B. Michael Ghadimi, Stefan Rose-John, Marian Grade, Jürgen Wienands

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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness by Vijayalakshmi Kari, Sanjay Kumar Raul, Jana Maria Henck, Julia Kitz, Frank Kramer, Robyn Laura Kosinsky, Nadine Übelmesser, Wael Yassin Mansour, Jessica Eggert, Melanie Spitzner, Zeynab Najafova, Holger Bastians, Marian Grade, Jochen Gaedcke, Florian Wegwitz, Steven A. Johnsen

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Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolitesResearch in context by Melanie S. Patzak, Vijayalakshmi Kari, Shilpa Patil, Feda H. Hamdan, Robert G. Goetze, Marius Brunner, Jochen Gaedcke, Julia Kitz, Duncan I. Jodrell, Frances M. Richards, Christian Pilarsky, Robert Gruetzmann, Petra Rümmele, Thomas Knösel, Elisabeth Hessmann, Volker Ellenrieder, Steven A. Johnsen, Albrecht Neesse

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Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation by Laura K. Godfrey, Jan Forster, Sven-Thorsten Liffers, Christopher Schröder, Johannes Köster, Leonie Henschel, Kerstin U. Ludwig, David Lähnemann, Marija Trajkovic-Arsic, Diana Behrens, Aldo Scarpa, Rita T. Lawlor, Kathrin E. Witzke, Barbara Sitek, Steven A. Johnsen, Sven Rahmann, Bernhard Horsthemke, Michael Zeschnigk, Jens T. Siveke

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Super enhancer regulation of cytokine-induced chemokine production in alcoholic hepatitis by Mengfei Liu, Sheng Cao, Li He, Jinhang Gao, Juan P. Arab, Huarui Cui, Weixia Xuan, Yandong Gao, Tejasav S. Sehrawat, Feda H. Hamdan, Meritxell Ventura-Cots, Josepmaria Argemi, William C. K. Pomerantz, Steven A. Johnsen, Jeong-Heon Lee, Fei Gao, Tamas Ordog, Philippe Mathurin, Alexander Revzin, Ramon Bataller, Huihuang Yan, Vijay H. Shah

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Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells by Karolin Walter, Eva Rodriguez-Aznar, Monica S. Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen, Laura Lerma, Nora Daiss, Lucas-Alexander Schulte, Zeynab Najafova, Frank Arnold, Valentyn Usachov, Ninel Azoitei, Mert Erkan, Andre Lechel, Tim H. Brümmendorf, Thomas Seufferlein, Alexander Kleger, Enrique Tabarés, Cagatay Günes, Steven A. Johnsen, Fabian Beier, Bruno Sainz, Patrick C. Hermann

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Estrogen receptor beta repurposes EZH2 to suppress oncogenic NFκB/p65 signaling in triple negative breast cancer by Kirsten G. M. Aspros, Jodi M. Carter, Tanya L. Hoskin, Vera J. Suman, Malayannan Subramaniam, Michael J. Emch, Zhenqing Ye, Zhifu Sun, Jason P. Sinnwell, Kevin J. Thompson, Xiaojia Tang, Esther P. B. Rodman, Xiyin Wang, Adam W. Nelson, Igor Chernukhin, Feda H. Hamdan, Elizabeth S. Bruinsma, Jason S. Carroll, Martin E. Fernandez-Zapico, Steven A. Johnsen, Krishna R. Kalari, Haojie Huang, Roberto A. Leon-Ferre, Fergus J. Couch, James N. Ingle, Matthew P. Goetz, John R. Hawse

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