Longterm outcomes of rheumatoid arthritis patients with severe osteoporosis treated with either Teriparatide or antiresorptive treatment – an observational study by Barbara Hauser, Kathryn Berg, Justine Lambert, Stuart H. Ralston

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Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status by Ilhame Diboun, Sachin Wani, Stuart H Ralston, Omar ME Albagha

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Prophylactic zoledronic acid therapy to prevent or modify Paget’s disease of bone progression in adults with SQSTM1 mutations: the ZiPP RCT by Jonathan Phillips, Deepak Subedi, Steff C Lewis, Catriona Keerie, Stuart H Ralston

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Probiotics prevent cartilage damage and progression of osteoarthritis in mice by Antonia Sophocleous, Asim Azfer, Carmen Huesa, Eleni Stylianou, Giovanny Rodriguez Blanco, Stuart H. Ralston

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Adult hypophosphatasia with a novel ALPL mutation: Report of an Indian kindred by Sanjay K. Bhadada, Rimesh Pal, Vandana Dhiman, Nerea Alonso, Stuart H. Ralston, Simran Kaur, Rajat Gupta

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Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone by Ilhame Diboun, Ilhame Diboun, Sachin Wani, Stuart H. Ralston, Omar M. E. Albagha, Omar M. E. Albagha

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The Paget's disease of bone risk gene PML is a negative regulator of osteoclast differentiation and bone resorption by Sachin Wani, Anna Daroszewska, Donald M. Salter, Rob J. van ‘t Hof, Stuart H. Ralston, Omar M. E. Albagha

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Zoledronic acid prevents pagetic-like lesions and accelerated bone loss in the p62P394L mouse model of Paget's disease by Anna Daroszewska, Lorraine Rose, Nadine Sarsam, Gemma Charlesworth, Amanda Prior, Kenneth Rose, Stuart H. Ralston, Robert J. van ‘t Hof

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Optineurin Negatively Regulates Osteoclast Differentiation by Modulating NF-κB and Interferon Signaling: Implications for Paget’s Disease by Rami Obaid, Sachin E. Wani, Asim Azfer, Toby Hurd, Ruth Jones, Philip Cohen, Stuart H. Ralston, Omar M.E. Albagha

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Protocol of a randomised trial of teriparatide followed by zoledronic acid to reduce fracture risk in adults with osteogenesis imperfecta by Jennifer Walsh, Catriona Keerie, Stuart H Ralston, Christopher J Weir, Muhammad K Javaid, WAYNE LAM, Bente L Langdahl, Jannie D Hald, Patricia Osborne

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ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta. by Thomas S Lisse, Frank Thiele, Helmut Fuchs, Wolfgang Hans, Gerhard K H Przemeck, Koichiro Abe, Birgit Rathkolb, Leticia Quintanilla-Martinez, Gabriele Hoelzlwimmer, Miep Helfrich, Eckhard Wolf, Stuart H Ralston, Martin Hrabé de Angelis

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Glutamine repeat variants in human RUNX2 associated with decreased femoral neck BMD, broadband ultrasound attenuation and target gene transactivation. by Nigel A Morrison, Alexandre A Stephens, Motomi Osato, Patsie Polly, Timothy C Tan, Namiko Yamashita, James D Doecke, Julie Pasco, Nicolette Fozzard, Graeme Jones, Stuart H Ralston, Philip N Sambrook, Richard L Prince, Geoff C Nicholson

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Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing miceResearch in context by Silvia Marino, Daniëlle de Ridder, Ryan T. Bishop, Nathalie Renema, Marco Ponzetti, Antonia Sophocleous, Mattia Capulli, Abdullah Aljeffery, Giovana Carrasco, Marianela Dalghi Gens, Asim Khogeer, Stuart H. Ralston, Jürg Gertsch, Francois Lamoureux, Dominique Heymann, Nadia Rucci, Aymen I. Idris

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Ubiquitin-protein ligase Ubr5 cooperates with hedgehog signalling to promote skeletal tissue homeostasis. by David Mellis, Katherine A Staines, Silvia Peluso, Ioanna Ch Georgiou, Natalie Dora, Malgorzata Kubiak, Rob Van't Hof, Michela Grillo, Colin Farquharson, Elaine Kinsella, Anna Thornburn, Stuart H Ralston, Donald M Salter, Natalia A Riobo-Del Galdo, Robert E Hill, Mark Ditzel

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Aged G Protein-Coupled Receptor Kinase 3 (Grk3)-Deficient Mice Exhibit Enhanced Osteoclastogenesis and Develop Bone Lesions Analogous to Human Paget’s Disease of Bone by Emily M. Rabjohns, Rishi R. Rampersad, Arin Ghosh, Katlyn Hurst, Amanda M. Eudy, Jaime M. Brozowski, Hyun Ho Lee, Yinshi Ren, Anthony Mirando, Justin Gladman, Jessica L. Bowser, Kathryn Berg, Sachin Wani, Stuart H. Ralston, Matthew J. Hilton, Teresa K. Tarrant

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Benefit of burosumab in adults with X-linked hypophosphataemia (XLH) is maintained with long-term treatment by Karine Briot, Wei Sun, Rachel K Crowley, Maria Luisa Brandi, Stuart H Ralston, Peter Kamenický, Martine Cohen-Solal, Richard Keen, Angela Williams, Muhammad K Javaid, Robin H Lachmann, Annabel Nixon, Mark Nixon, Anne-Lise Lecoq, Sami Kolta, Jennifer S Walsh, Angela J Rylands

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Harm, benefit and costs associated with low-dose glucocorticoids added to the treatment strategies for rheumatoid arthritis in elderly patients (GLORIA trial): study protocol for a... by Linda Hartman, Linda A. Rasch, Thomas Klausch, Hans W. J. Bijlsma, Robin Christensen, Yvo M. Smulders, Stuart H. Ralston, Frank Buttgereit, Maurizio Cutolo, Jose A. P. Da Silva, Daniela Opris, Jozef Rovenský, Szilvia Szamosi, Leonie M. Middelink, Willem F. Lems, Maarten Boers

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Effect of Denosumab or Alendronate on Vascular Calcification: Secondary Analysis of SALTIRE2 Randomized Controlled Trial by Jolien Geers, Rong Bing, Tania A. Pawade, Mhairi K. Doris, Marwa Daghem, Alexander J. Fletcher, Audrey C. White, Laura Forsyth, Emily Evans, Jacek Kwieciński, Michelle C. Williams, Edwin J. R. van Beek, Soongu Kwak, Frederique E.C.M. Peeters, Evangelos Tzolos, Piotr J Slomka, Christophe Lucatelli, Stuart H. Ralston, Bernard Prendergast, David E. Newby, Marc R. Dweck

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Opportunities and Challenges in Functional Genomics Research in Osteoporosis: Report From a Workshop Held by the Causes Working Group of the Osteoporosis and Bone Research Academy... by Jonathan H. Tobias, Jonathan H. Tobias, Emma L. Duncan, Erika Kague, Chrissy L. Hammond, Celia L. Gregson, Celia L. Gregson, Duncan Bassett, Graham R. Williams, Josine L. Min, Tom R. Gaunt, David Karasik, Claes Ohlsson, Fernando Rivadeneira, James R. Edwards, Fadil M. Hannan, John P. Kemp, John P. Kemp, Sophie J. Gilbert, Nerea Alonso, Neelam Hassan, Juliet E. Compston, Stuart H. Ralston

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Burosumab treatment in adults with X-linked hypophosphataemia: 96-week patient-reported outcomes and ambulatory function from a randomised phase 3 trial and open-label extension by Karine Briot, Rachel K Crowley, Maria Luisa Brandi, Stuart H Ralston, Han-Wook Yoo, Peter Kamenický, Takuo Kubota, Nobuaki Ito, Martine Cohen-Solal, Richard Keen, Angela Williams, Muhammad K Javaid, Hiroyuki Tanaka, Robin H Lachmann, Karl Insogna, Richard Eastell, Yasuhiro Takeuchi, Anthony A Portale, Thomas O Carpenter, Hae Ii Cheong, Yasuo Imanishi, Steven Ing, Suzanne Jan de Beur, Farzana Perwad, Pisit Pitukcheewanont, Thomas J Weber, Annabel Nixon, Mark Nixon, Erik A Imel

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