JoAnne Stubbe

Stubbe receiving [[National Medal of Science]] in 2009 JoAnne Stubbe (born June 11, 1946) is an American chemist best known for her work on ribonucleotide reductases, for which she was awarded the National Medal of Science in 2009. In 2017, she retired as a professor of chemistry and biology at the Massachusetts Institute of Technology. Provided by Wikipedia
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  1. 1
    5.08J / 7.08J Biological Chemistry II, Spring 2004

    5.08J / 7.08J Biological Chemistry II, Spring 2004 by Stubbe, JoAnne, Ting, Alice

    Published 2019
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  2. 2
    Clofarabine 5′-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit

    Clofarabine 5′-di and -triphosphates inhibit human ribonucleotide reductase by altering the quaternary structure of its large subunit by Aye, Yimon, Stubbe, JoAnne

    Published 2011
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  3. 3
    Bacillus subtilis Class Ib Ribonucleotide Reductase Is a Dimanganese(III)-Tyrosyl Radical Enzyme

    Bacillus subtilis Class Ib Ribonucleotide Reductase Is a Dimanganese(III)-Tyrosyl Radical Enzyme by Zhang, Yan, Stubbe, JoAnne

    Published 2012
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  4. 4
    Chemistry with an Artificial Primer of Polyhydroxybutyrate Synthase Suggests a Mechanism for Chain Termination

    Chemistry with an Artificial Primer of Polyhydroxybutyrate Synthase Suggests a Mechanism for Chain Termination by Stubbe, JoAnne, Buckley, Rachael M.

    Published 2016
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  5. 5
    Escherichia coli class Ib ribonucleotide reductase contains a dimanganese(III)-tyrosyl radical cofactor in vivo

    Escherichia coli class Ib ribonucleotide reductase contains a dimanganese(III)-tyrosyl radical cofactor in vivo by Cotruvo, Joseph A., Stubbe, JoAnne

    Published 2012
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  6. 6
    An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase

    An active dimanganese(III)-tyrosyl radical cofactor in Escherichia coli class Ib ribonucleotide reductase by Cotruvo, Joseph A., Stubbe, JoAnne

    Published 2012
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  7. 7
    Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F2CTP: covalent modification

    Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F2CTP: covalent modification by Lohman, Gregory J. S., Stubbe, JoAnne

    Published 2012
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  8. 8
    Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study

    Metallation and mismetallation of iron and manganese proteins in vitro and in vivo: the class I ribonucleotide reductases as a case study by Stubbe, JoAnne, Cotruvo, Joseph A.

    Published 2013
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  9. 9
    Control of metallation and active cofactor assembly in the class Ia and Ib ribonucleotide reductases: diiron or dimanganese?

    Control of metallation and active cofactor assembly in the class Ia and Ib ribonucleotide reductases: diiron or dimanganese? by Stubbe, JoAnne, Cotruvo, Joseph A.

    Published 2015
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  10. 10
    A hot oxidant, 3-NO[subscript 2]Y[subscript 122] radical, unmasks conformational gating in reductase

    A hot oxidant, 3-NO[subscript 2]Y[subscript 122] radical, unmasks conformational gating in reductase by Yokoyama, Kenichi, Uhlin, Ulla, Stubbe, JoAnne

    Published 2012
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  11. 11
    Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of pK[subscript a] Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase

    Site-Specific Incorporation of 3-Nitrotyrosine as a Probe of pK[subscript a] Perturbation of Redox-Active Tyrosines in Ribonucleotide Reductase by Yokoyama, Kenichi, Uhlin, Ulla, Stubbe, JoAnne

    Published 2012
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  12. 12
    Detection of Covalent and Noncovalent Intermediates in the Polymerization Reaction Catalyzed by a C149S Class III Polyhydroxybutyrate Synthase

    Detection of Covalent and Noncovalent Intermediates in the Polymerization Reaction Catalyzed by a C149S Class III Polyhydroxybutyrate Synthase by Li, Ping, Chakraborty, Sumit, Stubbe, JoAnne

    Published 2013
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  13. 13
    Charge-Transfer Dynamics at the α/β Subunit Interface of a Photochemical Ribonucleotide Reductase

    Charge-Transfer Dynamics at the α/β Subunit Interface of a Photochemical Ribonucleotide Reductase by Olshansky, Lisa, Stubbe, JoAnne, Nocera, Daniel G.

    Published 2017
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  14. 14
    Use of 2,3,5-F[subscript 3]Y-beta 2 and 3-NH[subscript 2]Y-alpha 2 To Study Proton-Coupled Electron Transfer in Escherichia coli Ribonucleotide Reductase

    Use of 2,3,5-F[subscript 3]Y-beta 2 and 3-NH[subscript 2]Y-alpha 2 To Study Proton-Coupled Electron Transfer in Escherichia coli Ribonucleotide Reductase by Seyedsayamdost, Mohammad R., Yee, Cyril S., Stubbe, JoAnne

    Published 2012
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  15. 15
    Bacillus Subtilis Class Ib Ribonucleotide Reductase: High Activity and Dynamic Subunit Interactions

    Bacillus Subtilis Class Ib Ribonucleotide Reductase: High Activity and Dynamic Subunit Interactions by Zhu, Xuling, Stubbe, JoAnne, Parker, Mackenzie James

    Published 2015
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  16. 16
    Mechanistic Insight with HBCH[subscript 2]CoA as a Probe to Polyhydroxybutyrate (PHB) Synthases

    Mechanistic Insight with HBCH[subscript 2]CoA as a Probe to Polyhydroxybutyrate (PHB) Synthases by Zhang, Wei, Shrestha, Ruben, Buckley, Rachael M., Jewell, Jamie, Bossmann, Stefan H., Stubbe, JoAnne, Li, Ping, Stubbe, JoAnne

    Published 2015
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  17. 17
    Reversible, Long-Range Radical Transfer in E. coli Class Ia Ribonucleotide Reductase

    Reversible, Long-Range Radical Transfer in E. coli Class Ia Ribonucleotide Reductase by Minnihan, Ellen Catherine, Stubbe, JoAnne, Nocera, Daniel G.

    Published 2017
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  18. 18
    Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F2CTP: adenosylcobalamin destruction and formation of a nucleotide based radical

    Inactivation of Lactobacillus leichmannii ribonucleotide reductase by F2CTP: adenosylcobalamin destruction and formation of a nucleotide based radical by Lohman, Gregory J. S., Gerfen, Gary J., Stubbe, JoAnne

    Published 2012
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  19. 19
    Use of 3-Aminotyrosine To Examine the Pathway Dependence of Radical Propagation in Escherichia coli Ribonucleotide Reductase

    Use of 3-Aminotyrosine To Examine the Pathway Dependence of Radical Propagation in Escherichia coli Ribonucleotide Reductase by Minnihan, Ellen Catherine, Seyedsayamdost, Mohammad R., Stubbe, JoAnne

    Published 2013
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  20. 20
    Formal Reduction Potential of 3,5-Difluorotyrosine in a Structured Protein: Insight into Multistep Radical Transfer

    Formal Reduction Potential of 3,5-Difluorotyrosine in a Structured Protein: Insight into Multistep Radical Transfer by Liang, Li, Stubbe, JoAnne, Tommos, Cecilia, Ravichandran, Kanchana

    Published 2015
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