A common biological basis of obesity and nicotine addiction. by Thorgeirsson, T, Gudbjartsson, D, Sulem, P, Besenbacher, S, Styrkarsdottir, U, Thorleifsson, G, Walters, G, Furberg, H, Sullivan, P, Marchini, J, McCarthy, M, Steinthorsdottir, V, Thorsteinsdottir, U, Stefansson, K

Linkage of osteoporosis to chromosome 20p12 and association to BMP2 by Styrkarsdottir, U, Cazier, J, Kong, A, Rolfsson, O, Larsen, H, Bjarnadottir, E, Johannsdottir, V, Sigurdardottir, MS, Bagger, Y, Christiansen, C, Reynisdottir, I, Grant, S, Jonasson, K, Frigge, M, Gulcher, JR, Sigurdsson, G, Stefansson, K

A genome-wide association study identifies a common variant near the GRP22 gene as a new locus involved in prevalence and progression of osteoarthritis by Kerkhof, H, Jonsdottir, I, Meulenbelt, I, Stolk, L, Valdes, A, Zhai, G, Zhu, Y, Doherty, M, Doherty, S, Tsezou, A, Gonzalez, A, Carr, A, Felson, D, Styrkarsdottir, U, Slagboom, E, Loughlin, J, Rivadeneira, F, Hofman, A, Pols, H, Spector, T, Uitterlinden, A, van Meurs, J

The genetic basis of cross-phenotype correlation with bone fracture risk: the GEFOS consortium by Oei, L, Nordstrom, P, Ntzani, E, Zheng, H, Estrada, K, Duncan, E, Medina-Gomez, C, Kaptoge, S, Hsu, Y, Yang, J, Nielson, C, Styrkarsdottir, U, Ridker, P, Garcia, M, Aragaki, A, Enneman, A, Lehtimaki, T, Esko, T, Trompet, S, Eriksson, J, Amin, N, Kung, A, Tsilidis, K, Thorleifsson, G, Rose, L

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22. by Evangelou, E, Valdes, A, Kerkhof, H, Styrkarsdottir, U, Zhu, Y, Meulenbelt, I, Lories, R, Karassa, F, Tylzanowski, P, Bos, S, Akune, T, Arden, N, Carr, A, Chapman, K, Cupples, L, Dai, J, Deloukas, P, Doherty, M, Doherty, S, Engstrom, G, Gonzalez, A, Halldorsson, B, Hammond, C, Hart, D, Helgadottir, H

Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31. by Styrkarsdottir, U, Thorleifsson, G, Helgadottir, H, Bomer, N, Metrustry, S, Bierma-Zeinstra, S, Strijbosch, A, Evangelou, E, Hart, D, Beekman, M, Jonasdottir, A, Sigurdsson, A, Eiriksson, F, Thorsteinsdottir, M, Frigge, M, Kong, A, Gudjonsson, SA, Magnusson, O, Masson, G, Hofman, A, Arden, N, Ingvarsson, T, Lohmander, S, Kloppenburg, M, Rivadeneira, F

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture by Estrada, K, Styrkarsdottir, U, Evangelou, E, Hsu, Y, Duncan, E, Ntzani, E, Oei, L, Albagha, O, Amin, N, Kemp, J, Koller, D, Li, G, Liu, C, Minster, R, Moayyeri, A, Vandenput, L, Willner, D, Xiao, S, Yerges-Armstrong, L, Zheng, H, Alonso, N, Eriksson, J, Kammerer, C, Kaptoge, S, Leo, P

Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22 by Evangelou, E, Valdes, A, Kerkhof, H, Styrkarsdottir, U, Zhu, Y, Meulenbelt, I, Lories, R, Karassa, F, Tylzanowski, P, Bos, S, Rayner, N, Southam, L, Zhai, G, Elliott, K, Hunt, SE, Blackburn, H, Potter, S, Day-Williams, A, Beazley, C, Akune, T, Arden, N, Carr, A, Chapman, K, Cupples, L, Dai, J

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. by Estrada, K, Styrkarsdottir, U, Evangelou, E, Hsu, Y, Duncan, E, Ntzani, E, Oei, L, Albagha, O, Amin, N, Kemp, J, Koller, D, Li, G, Liu, C, Minster, R, Moayyeri, A, Vandenput, L, Willner, D, Xiao, S, Yerges-Armstrong, L, Zheng, H, Alonso, N, Eriksson, J, Kammerer, C, Kaptoge, S, Leo, P

A genome-wide copy number association study of osteoporotic fractures points to the 6p25.1 locus. by Oei, L, Hsu, Y, Styrkarsdottir, U, Eussen, B, de Klein, A, Peters, M, Halldorsson, B, Liu, C, Alonso, N, Kaptoge, S, Thorleifsson, G, Hallmans, G, Hocking, L, Husted, L, Jameson, K, Kruk, M, Lewis, JR, Patel, MS, Scollen, S, Svensson, O, Trompet, S, van Schoor, N, Zhu, K, Buckley, B, Cooper, C

Association analyses of 47,500 individuals identifies six fracture loci and 82 BMD loci clustering in biological pathways that regulate osteoblast and osteoclast activity by Estrada, K, Evangelou, E, Hsu, Y, Styrkarsdottir, U, Liu, C, Moayyeri, A, Kaptoge, S, Duncan, E, Amin, N, Kiel, D, Karasik, D, Albagha, O, Brown, M, Spector, T, Zillikens, M, Ohlsson, C, Thorleifsson, G, Reeve, J, Vandenput, L, Pettersson, U, O'Neill, T, Riancho, J, Ijunggren, O, Rousseau, F, Leslie, W

COMMON VARIANTS IN SKELETAL DYSPLASIA GENES ARE ASSOCIATED WITH OSTEOARTHRITIS by Kerkhof, H, Panagiotou, O, Irving, M, Esko, T, Meulenbelt, I, Panoutsopoulou, K, Styrkarsdottir, U, Zhu, Y, Cupples, A, Felson, D, Kloppenburg, M, Arden, N, Albert, H, Slagboom, E, Frank, L, Metspalu, A, Ioannidis, J, Jonsdottir, I, Stefansson, K, Spector, T, Uitterlinden, A, Zeggini, E, Valdes, A, Evangelou, V, van Meurs, J

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations. by Valdes, A, Styrkarsdottir, U, Doherty, M, Morris, D, Mangino, M, Tamm, A, Doherty, SA, Kisand, K, Kerna, I, Tamm, A, Wheeler, M, Maciewicz, R, Zhang, W, Muir, K, Dennison, E, Hart, D, Metrustry, S, Jonsdottir, I, Jonsson, G, Jonsson, H, Ingvarsson, T, Cooper, C, Vyse, T, Spector, T, Stefansson, K, Arden, N

Functional characterization of GWAS loci associated with fracture risk by Oei, L, Reppe, S, Ntzani, E, Hibbs, M, Choi, K, Zheng, H, Estrada, K, van de Peppel, J, Nielson, C, Styrkarsdottir, U, Ridker, P, Hsu, Y, Garcia, M, Aragaki, A, Duncan, E, Enneman, A, Lehtimaki, T, Esko, T, Trompet, S, Kaptoge, S, Eriksson, J, Amin, N, Kung, A, Medina-Gomez, C, Tsilidis, K

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. by Evangelou, E, Kerkhof, H, Styrkarsdottir, U, Ntzani, E, Bos, S, Esko, T, Evans, D, Metrustry, S, Panoutsopoulou, K, Ramos, Y, Thorleifsson, G, Tsilidis, K, Arden, N, Aslam, N, Bellamy, N, Birrell, F, Blanco, F, Carr, A, Chapman, K, Day-Williams, A, Deloukas, P, Doherty, M, Engström, G, Helgadottir, H, Hofman, A

Novel genetic variants for cartilage thickness and hip osteoarthritis by Castaño-Betancourt, MC, Evans, DS, Ramos, YF, Boer, CG, Metrustry, S, Liu, Y, Hollander, W, van Rooij, J, Kraus, VB, Yau, MS, Mitchell, BD, Muir, K, Hofman, A, Doherty, M, Doherty, S, Zhang, W, Kraaij, R, Rivadeneira, F, Barrett-Connor, E, Maciewicz, RA, Arden, N, Nelissen, RG, Kloppenburg, M, Jordan, JM, Nevitt, MC, Slagboom, EP, Hart, DJ, Lafeber, F, Styrkarsdottir, U, Zeggini, E, Evangelou, E, Spector, TD, Uitterlinden, AG, Lane, NE, Meulenbelt, I, Valdes, AM, van Meurs, JB

Genome-wide association study using extreme truncate selection identifies novel genes affecting bone mineral density and fracture risk. by Duncan, E, Danoy, P, Kemp, J, Leo, P, McCloskey, E, Nicholson, G, Eastell, R, Prince, R, Eisman, J, Jones, G, Sambrook, P, Reid, I, Dennison, E, Wark, J, Richards, J, Uitterlinden, A, Spector, T, Esapa, C, Cox, R, Brown, S, Thakker, R, Addison, K, Bradbury, L, Center, JR, Cooper, C, Cremin, C, Estrada, K, Felsenberg, D, Gluer, C, Hadler, J, Henry, M, Hofman, A, Kotowicz, M, Makovey, J, Nguyen, S, Nguyen, T, Pasco, J, Pryce, K, Reid, D, Rivadeneira, F, Roux, C, Stefansson, K, Styrkarsdottir, U, Thorleifsson, G, Tichawangana, R, Evans, D, Brown, M

Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria by Day, F, Karaderi, T, Jones, MR, Meun, C, He, C, Drong, A, Kraft, P, Lin, N, Huang, H, Broer, L, Magi, R, Saxena, R, Laisk, T, Urbanek, M, Hayes, MG, Thorleifsson, G, Fernandez-Tajes, J, Mahajan, A, Mullin, BH, Stuckey, BGA, Spector, TD, Wilson, SG, Goodarzi, MO, Davis, L, Obermayer-Pietsch, B, Uitterlinden, AG, Anttila, V, Neale, BM, Jarvelin, M-R, Fauser, B, Kowalska, I, Visser, JA, Andersen, M, Ong, K, Stener-Victorin, E, Ehrmann, D, Legro, RS, Salumets, A, McCarthy, MI, Morin-Papunen, L, Thorsteinsdottir, U, Stefansson, K, 23Andme Research Team, Styrkarsdottir, U, Perry, JRB, Dunaif, A, Laven, J, Franks, S, Lindgren, CM, Welt, CK

Disentangling the genetics of lean mass by Karasik, D, Zillikens, MC, Hsu, Y-H, Aghdassi, A, Akesson, K, Amin, N, Barroso, I, Bennett, DA, Bertram, L, Bochud, M, Borecki, IB, Broer, L, Buchman, AS, Byberg, L, Campbell, H, Campos-Obando, N, Cauley, JA, Cawthon, PM, Chambers, JC, Chen, Z, Cho, NH, Choi, HJ, Chou, W-C, Cummings, SR, De Groot, LCPGM, De Jager, PL, Demuth, I, Diatchenko, L, Econs, MJ, Eiriksdottir, G, Enneman, AW, Eriksson, J, Eriksson, JG, Estrada, K, Evans, DS, Feitosa, MF, Fu, M, Gieger, C, Grallert, H, Gudnason, V, Lenore, LJ, Hayward, C, Hofman, A, Homuth, G, Huffman, KM, Husted, LB, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Johnson, T, Biffar, R, Jordan, JM, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, TO, Klopp, N, Kloth, JSL, Koller, DL, Kooner, JS, Kraus, WE, Kritchevsky, S, Kutalik, Z, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, BL, Lerch, MM, Lewis, JR, Lill, C, Lind, L, Lindgren, C, Liu, Y, Livshits, G, Ljunggren, Ö, Loos, RJF, Lorentzon, M, Luan, J, Luben, RN, Malkin, I, McGuigan, FE, Medina-Gomez, C, Meitinger, T, Melhus, H, Mellström, D, Michaëlsson, K, Mitchell, BD, Morris, AP, Mosekilde, L, Nethander, M, Newman, AB, O'Connell, JR, Oostra, BA, Orwoll, ES, Palotie, A, Peacock, M, Perola, M, Peters, A, Prince, RL, Psaty, BM, Räikkönen, K, Ralston, SH, Ripatti, S, Rivadeneira, F, Robbins, JA, Rotter, JI, Rudan, I, Salomaa, V, Satterfield, S, Schipf, S, Shin, CS, Smith, AV, Smith, SB, Soranzo, N, Spector, TD, Stancáková, A, Stefansson, K, Steinhagen-Thiessen, E, Stolk, L, Streeten, EA, Styrkarsdottir, U, Swart, KMA, Thompson, P, Thomson, CA, Thorleifsson, G, Thorsteinsdottir, U, Tikkanen, E, Tranah, GJ, Uitterlinden, AG, Van Duijn, CM, Van Schoor, NM, Vandenput, L, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Wareham, N, Waterworth, D, Weedon, MN, Wichmann, H-E, Widen, E, Williams, FMK, Wilson, JF, Wright, NC, Yerges-Armstrong, LM, Yu, L, Zhang, W, Zhao, JH, Zhou, Y, Nielson, CM, Harris, TB, Demissie, S, Kiel, DP, Ohlsson, C

Whole‐genome sequencing identifies EN1 as a determinant of bone density and fracture by Zheng, H, Forgetta, V, Hsu, Y-H, Estrada, K, Rosello-Diez, A, Leo, PJ, Dahia, C, Park-Min, K, Tobias, J, Kooperberg, C, Kleinman, A, Styrkarsdottir, U, Liu, C, Uggla, C, Evans, D, Nielson, C, Walter, K, Pettersson-Kymmer, U, McCarthy, S, Eriksson, J, Kwan, T, Jhamai, M, Trajanoska, K, Memari, Y, Min, J, Huang, J, Danecek, P, Wilmot, B, Li, R, Chou, W, Mokry, L, Moayyeri, A, Claussnitzer, M, Cheng, C, Cheung, W, Medina-Gómez, C, Ge, B, Chen, S, Choi, K, Oei, L, Fraser, J, Kraaij, R, Hibbs, M, Gregson, C, Paquette, D, Hofman, A, Wibom, C, Tranah, G, Marshall, M, Gardiner, B, Cremin, K, Auer, P, Hsu, L, Ring, S, Tung, J, Thorleifsson, G, Enneman, A, van Schoor, N, de Groot, L, van der Velde, N, Melin, B, Kemp, J, Christiansen, C, Sayers, A, Zhou, Y, Calderari, S, van Rooij, J, Carlson, C, Peters, U, Berlivet, S, Dostie, J, Uitterlinden, A, Williams, S, Farber, C, Grinberg, D, LaCroix, A, Haessler, J, Chasman, D, Giulianini, F, Rose, L, Ridker, P, Eisman, J, Nguyen, T, Center, J, Nogues, X, Garcia-Giralt, N, Launer, L, Gudnason, V, Mellström, D, Vandenput, L, Amin, N, van Duijn, C, Karlsson, M, Ljunggren, Ö, Svensson, O, Hallmans, G, Rousseau, F, Giroux, S, Bussière, J, Arp, P, Koromani, F, Prince, R, Lewis, J, Langdahl, B, Hermann, A, Jensen, J, Kaptoge, S, Khaw, K, Reeve, J, Formosa, M, Xuereb-Anastasi, A, Åkesson, K, McGuigan, F, Garg, G, Olmos, J, Zarrabeitia, M, Riancho, J, Ralston, S, Alonso, N, Jiang, X, Goltzman, D, Pastinen, T, Grundberg, E, Gauguier, D, Orwoll, E, Karasik, D, Davey-Smith, G, Smith, A, Siggeirsdottir, K, Harris, T, Zillikens, M, van Meurs, J, Thorsteinsdottir, U, Maurano, M, Timpson, N, Soranzo, N, Durbin, R, Wilson, S, Ntzani, E, Brown, M, Stefansson, K, Hinds, D, Spector, T, Cupples, L, Ohlsson, C, Greenwood, C, Jackson, R, Rowe, D, Loomis, C, Evans, D, Ackert-Bicknell, C, Joyner, A, Duncan, E, Kiel, D, Rivadeneira, F, Richards, J