Tissue-specific expansion of Zika virus isogenic variants drive disease pathogenesisResearch in context od Kitti Wing Ki Chan, Amanda Makha Bifani, Satoru Watanabe, Milly M. Choy, Eng Eong Ooi, Subhash G. Vasudevan

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High affinity human antibody fragments to dengue virus non-structural protein 3. od Nicole J Moreland, Moon Y F Tay, Elfin Lim, Prasad N Paradkar, Danny N P Doan, Yin Hoe Yau, Susana Geifman Shochat, Subhash G Vasudevan

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Host gene expression profiling of dengue virus infection in cell lines and patients. od Joshua Fink, Feng Gu, Ling Ling, Thomas Tolfvenstam, Farzad Olfat, Keh Chuang Chin, Pauline Aw, Joshy George, Vladimir A Kuznetsov, Mark Schreiber, Subhash G Vasudevan, Martin L Hibberd

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Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection od Clement Yau, Esther Shuyi Gan, Swee Sen Kwek, Hwee Cheng Tan, Eugenia Z. Ong, Noor Zayanah Hamis, Laura Rivino, Kuan Rong Chan, Satoru Watanabe, Subhash G. Vasudevan, Eng Eong Ooi

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The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production. od Moon Y F Tay, Kate Smith, Ivan H W Ng, Kitti W K Chan, Yongqian Zhao, Eng Eong Ooi, Julien Lescar, Dahai Luo, David A Jans, Jade K Forwood, Subhash G Vasudevan

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A human PrM antibody that recognizes a novel cryptic epitope on dengue E glycoprotein. od Annie Hoi Yi Chan, Hwee Cheng Tan, Angelia Yee Chow, Angeline Pei Chiew Lim, Shee Mei Lok, Nicole J Moreland, Subhash G Vasudevan, Paul A MacAry, Eng Eong Ooi, Brendon J Hanson

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Structural basis of Zika virus NS1 multimerization and human antibody recognition od Bing Liang Alvin Chew, An Qi Ngoh, Wint Wint Phoo, Mei Jie Grace Weng, Ho Jun Sheng, Kitti Wing Ki Chan, Eddie Yong Jun Tan, Terri Gelbart, Chenrui Xu, Gene S. Tan, Subhash G. Vasudevan, Dahai Luo

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Sulfated polysaccharide, curdlan sulfate, efficiently prevents entry/fusion and restricts antibody-dependent enhancement of dengue virus infection in vitro: a possible candidate fo... od Koji Ichiyama, Sindhoora Bhargavi Gopala Reddy, Li Feng Zhang, Wei Xin Chin, Tegshi Muschin, Lars Heinig, Youichi Suzuki, Haraprasad Nanjundappa, Yoshiyuki Yoshinaka, Akihide Ryo, Nobuo Nomura, Eng Eong Ooi, Subhash G Vasudevan, Takashi Yoshida, Naoki Yamamoto

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Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. od Lukas Tanner, Mark Schreiber, Jenny G H Low, Adrian Ong, Thomas Tolfvenstam, Yee Ling Lai, Lee Ching Ng, Yee Sin Leo, Le Thi Puong, Subhash G Vasudevan, Cameron P Simmons, Martin L Hibberd, Eng Eong Ooi

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A crystal structure of the Dengue virus NS5 protein reveals a novel inter-domain interface essential for protein flexibility and virus replication. od Yongqian Zhao, Tingjin Sherryl Soh, Jie Zheng, Kitti Wing Ki Chan, Wint Wint Phoo, Chin Chin Lee, Moon Y F Tay, Kunchithapadam Swaminathan, Tobias C Cornvik, Siew Pheng Lim, Pei-Yong Shi, Julien Lescar, Subhash G Vasudevan, Dahai Luo

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Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development od Clement Yau, John Z.H. Low, Esther S. Gan, Swee Sen Kwek, Liang Cui, Hwee Cheng Tan, Darren Z.L. Mok, Candice Y.Y. Chan, October M. Sessions, Satoru Watanabe, Subhash G. Vasudevan, Yie Hou Lee, Kuan Rong Chan, Eng Eong Ooi

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The early clinical features of dengue in adults: challenges for early clinical diagnosis. od Jenny G H Low, Adrian Ong, Li Kiang Tan, Shera Chaterji, Angelia Chow, Wen Yan Lim, Koon Wui Lee, Robert Chua, Choon Rong Chua, Sharon W S Tan, Yin Bun Cheung, Martin L Hibberd, Subhash G Vasudevan, Lee-Ching Ng, Yee Sin Leo, Eng Eong Ooi

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Secreted dengue virus NS1 from infection is predominantly dimeric and in complex with high-density lipoprotein od Bing Liang Alvin Chew, AN Qi Ngoh, Wint Wint Phoo, Kitti Wing Ki Chan, Zheng Ser, Nikhil K Tulsian, Shiao See Lim, Mei Jie Grace Weng, Satoru Watanabe, Milly M Choy, Jenny Low, Eng Eong Ooi, Christiane Ruedl, Radoslaw M Sobota, Subhash G Vasudevan, Dahai Luo

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Characterization of RyDEN (C19orf66) as an Interferon-Stimulated Cellular Inhibitor against Dengue Virus Replication. od Youichi Suzuki, Wei-Xin Chin, Qi'En Han, Koji Ichiyama, Ching Hua Lee, Zhi Wen Eyo, Hirotaka Ebina, Hirotaka Takahashi, Chikako Takahashi, Beng Hui Tan, Takayuki Hishiki, Kenji Ohba, Toshifumi Matsuyama, Yoshio Koyanagi, Yee-Joo Tan, Tatsuya Sawasaki, Justin Jang Hann Chu, Subhash G Vasudevan, Kouichi Sano, Naoki Yamamoto

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A systematic approach to the development of a safe live attenuated Zika vaccine od Swee Sen Kwek, Satoru Watanabe, Kuan Rong Chan, Eugenia Z. Ong, Hwee Cheng Tan, Wy Ching Ng, Mien T. X. Nguyen, Esther S. Gan, Summer L. Zhang, Kitti W. K. Chan, Jun Hao Tan, October M. Sessions, Menchie Manuel, Julien Pompon, Camillus Chua, Sharifah Hazirah, Karl Tryggvason, Subhash G. Vasudevan, Eng Eong Ooi

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Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients. od Cynthia Sung, Yuan Wei, Satoru Watanabe, How Sung Lee, Yok Moi Khoo, Lu Fan, Abhay P S Rathore, Kitti Wing-Ki Chan, Milly M Choy, Uma S Kamaraj, October M Sessions, Pauline Aw, Paola F de Sessions, Bernett Lee, John E Connolly, Martin L Hibberd, Dhanasekaran Vijaykrishna, Limin Wijaya, Eng Eong Ooi, Jenny Guek-Hong Low, Subhash G Vasudevan

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