The mystery of missing heritability: Genetic interactions create phantom heritability by Sunyaev, Shamil R., Lander, Eric Steven

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Computational and statistical approaches to analyzing variants identified by exome sequencing by Stitziel, Nathan O., Kiezun, Adam, Sunyaev, Shamil R.

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Computational and statistical approaches to analyzing variants identified by exome sequencing by Stitziel, Nathan O., Kiezun, Adam, Sunyaev, Shamil R.

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Impact of deleterious passenger mutations on cancer progression by Korolev, Kirill Sergeevich, Sunyaev, Shamil R., McFarland, Christopher D., Kryukov, Gregory V., Mirny, Leonid A

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Identification of cancer driver genes based on nucleotide context by Dietlein, Felix, Weghorn, Donate, Taylor-Weiner, Amaro, Richters, André, Reardon, Brendan, Liu, David, Lander, Eric S, Van Allen, Eliezer M, Sunyaev, Shamil R

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Identification of cancer driver genes based on nucleotide context by Dietlein, Felix, Weghorn, Donate, Taylor-Weiner, Amaro, Richters, André, Reardon, Brendan, Liu, David, Lander, Eric S., Van Allen, Eliezer M., Sunyaev, Shamil R.

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Quantifying unobserved protein-coding variants in human populations provides a roadmap for large-scale sequencing projects by Zou, James, Valiant, Gregory, Valiant, Paul, Karczewski, Konrad, Chan, Siu On, Samocha, Kaitlin, Lek, Monkol, MacArthur, Daniel G., Sunyaev, Shamil R., Daly, Mark J.

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Searching for missing heritability: Designing rare variant association studies by Zuk, Or, Schaffner, Stephen F., Samocha, Kaitlin, Do, Ron, Hechter, Eliana, Kathiresan, Sekar, Daly, Mark J., Neale, Benjamin M., Sunyaev, Shamil R., Lander, Eric Steven

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Mutation mapping and identification by whole-genome sequencing by Leshchiner, Ignaty, Alexa, Kristen, Kelsey, Peter, Adzhubey, Ivan, Austin-Tse, Christina A., Cooney, Jeffrey D., Anderson, Heidi, King, Matthew J., Stottmann, Rolf W., Garnaas, Maija K., Ha, Seungshin, Drummond, Iain A., Paw, Barry H., North, Trista E., Beier, David R., Goessling, Wolfram, Sunyaev, Shamil R.

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Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy by Kousi, Maria, Söylemez, Onuralp, Ozanturk, Aysegül, Mourtzi, Niki, Akle, Sebastian, Jungreis, Irwin, Muller, Jean, Cassa, Christopher A, Brand, Harrison, Mokry, Jill Anne, Wolf, Maxim Y, Sadeghpour, Azita, McFadden, Kelsey, Lewis, Richard A, Talkowski, Michael E, Dollfus, Hélène, Kellis, Manolis, Davis, Erica E, Sunyaev, Shamil R, Katsanis, Nicholas

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Evidence for secondary-variant genetic burden and non-random distribution across biological modules in a recessive ciliopathy by Kousi, Maria, Söylemez, Onuralp, Ozanturk, Aysegül, Mourtzi, Niki, Akle, Sebastian, Jungreis, Irwin, Muller, Jean, Cassa, Christopher A, Brand, Harrison, Mokry, Jill Anne, Wolf, Maxim Y., Sadeghpour, Azita, McFadden, Kelsey, Lewis, Richard A, Talkowski, Michael E, Dollfus, Hélène, Kellis, Manolis, Davis, Erica E, Sunyaev, Shamil R, Katsanis, Nicholas

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The Parkinson’s disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability by Hallacli, Erinc, Kayatekin, Can, Nazeen, Sumaiya, Wang, Xiou H, Sheinkopf, Zoe, Sathyakumar, Shubhangi, Sarkar, Souvarish, Jiang, Xin, Dong, Xianjun, Di Maio, Roberto, Wang, Wen, Keeney, Matthew T, Felsky, Daniel, Sandoe, Jackson, Vahdatshoar, Aazam, Udeshi, Namrata D, Mani, DR, Carr, Steven A, Lindquist, Susan, De Jager, Philip L, Bartel, David P, Myers, Chad L, Greenamyre, J Timothy, Feany, Mel B, Sunyaev, Shamil R, Chung, Chee Yeun, Khurana, Vikram

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An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge by Brownstein, Catherine A., Beggs, Alan H., Homer, Nils, Merriman, Barry, Yu, Timothy W., Flannery, Katherine C., DeChene, Elizabeth T., Towne, Meghan C., Savage, Sarah K., Price, Emily N., Holm, Ingrid A., Luquette, Lovelace J., Lyon, Elaine, Majzoub, Joseph, Neupert, Peter, McCallie Jr., David, Szolovits, Peter, Willard, Huntington F., Mendelsohn, Nancy J., Temme, Renee, Finkel, Richard S., Yum, Sabrina W., Medne, Livija, Sunyaev, Shamil R., Adzhubey, Ivan, Cassa, Christopher A., de Bakker, Paul I. W., Duzkale, Hatice, Dworzyński, Piotr, Fairbrother, William G., Francioli, Laurent, Funke, Birgit H., Giovanni, Monica A., Handsaker, Robert E., Lage, Kasper, Lebo, Matthew S., Lek, Monkol, Leshchiner, Ignaty, MacArthur, Daniel G., McLaughlin, Heather M., Murray, Michael F., Pers, Tune H., Polak, Paz P., Raychaudhuri, Soumya, Rehm, Heidi L., Soemedi, Rachel, Stitziel, Nathan O., Vestecka, Sara, Supper, Jochen, Gugenmus, Claudia, Klocke, Bernward, Hahn, Alexander, Schubach, Max, Menzel, Mortiz, Biskup, Saskia, Freisinger, Peter, Deng, Mario, Braun, Martin, Perner, Sven, Smith, Richard J. H., Andorf, Janeen L., Huang, Jian, Ryckman, Kelli, Sheffield, Val C., Stone, Edwin M., Bair, Thomas, Black-Ziegelbein, E. A., Braun, Terry A., Darbro, Benjamin, DeLuca, Adam P., Kolbe, Diana L., Scheetz, Todd E., Shearer, Aiden E., Sompallae, Rama, Wang, Kai, Bassuk, Alexander G., Edens, Erik, Mathews, Katherine, Moore, Steven A., Shchelochkov, Oleg A., Trapane, Pamela, Bossler, Aaron, Campbell, Colleen A., Heusel, Jonathan W., Kwitek, Anne, Maga, Tara, Panzer, Karin, Wassink, Thomas, Van Daele, Douglas, Azaiez, Hela, Booth, Kevin, Meyer, Nic, Segal, Michael M., Williams, Marc S., Tromp, Gerard, White, Peter, Corsmeier, Donald, Fitzgerald-Butt, Sara, Herman, Gail, Lamb-Thrush, Devon, McBride, Kim L., Newsom, David, Pierson, Christopher R., Rakowsky, Alexander T., Maver, Ales, Lovrečić, Luca, Palandacic, Anja, Peterlin, Borut, Torkamani, Ali, Wedell, Anna, Huss, Mikael, Alexeyenko, Andrey, Lindvall, Jessica M., Magnusson, Mans, Nilsson, Daniel, Stranneheim, Henrik, Taylan, Fulya, Gilissen, Christian, Hoischen, Alexander, van Bon, Bregje, Yntema, Helger, Nelen, Marcel, Zhang, Weidong, Sager, Jason, Zhang, Lu, Blair, Kathryn, Kural, Deniz, Cariaso, Michael, Lennon, Greg G., Javed, Asif, Agrawal, Saloni, Ng, Pauline C., Sandhu, Komal S., Krishna, Shuba, Veeramachaneni, Vamsi, Isakov, Ofer, Halperin, Eran, Friedman, Eitan, Shomron, Noam, Glusman, Gustavo, Roach, Jared C., Caballero, Juan, Cox, Hannah C., Mauldin, Denise, Ament, Seth A., Rowen, Lee, Richards, Daniel R., Lucas, F Anthony S., Gonzalez-Garay, Manuel L., Caskey, C. T., Bai, Yu, Huang, Ying, Fang, Fang, Zhang, Yan, Wang, Zhengyuan, Barrera, Jorge, Garcia-Lobo, Juan M., González-Lamuno, Domingo, Llorca, Javier, Rodriguez, Maria C., Varela, Ignacio, Reese, Martin G., De La Vega, Francisco M., Kiruluta, Edward, Cargill, Michele, Hart, Reece K., Sorenson, Jon M., Lyon, Gholson J., Stevenson, David A., Bray, Bruce E., Moore, Barry M., Eilbeck, Karen, Yandell, Mark, Zhao, Hongyu, Hou, Lin, Chen, Xiaowei, Yan, Xiting, Chen, Mengjie, Li, Cong, Yang, Can, Gunel, Murat, Li, Peining, Kong, Yong, Alexander, Austin C., Albertyn, Zayed I., Boycott, Kym M., Bulman, Dennis E., Gordon, Paul M. K., Innes, A. M., Knoppers, Bartha M., Majewski, Jacek, Marshall, Christian R., Parboosingh, Jillian S., Sawyer, Sarah L., Samuels, Mark E., Schwartzentruber, Jeremy, Kohane, Isaac, Margulies, David M.

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