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A Conserved Acidic Residue in the C-Terminal Flexible Loop of HIV-1 Nef Contributes to the Activity of SERINC5 and CD4 Downregulation by Claudia Firrito, Cinzia Bertelli, Annachiara Rosa, Ajit Chande, Swetha Ananth, Hannah van Dijk, Oliver T. Fackler, Charlotte Stoneham, Rajendra Singh, John Guatelli, Massimo Pizzato
Published 2023-02-01
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SIVcol Nef counteracts SERINC5 by promoting its proteasomal degradation but does not efficiently enhance HIV-1 replication in human CD4+ T cells and lymphoid tissue. by Dorota Kmiec, Bengisu Akbil, Swetha Ananth, Dominik Hotter, Konstantin M J Sparrer, Christina M Stürzel, Birthe Trautz, Ahidjo Ayouba, Martine Peeters, Zhong Yao, Igor Stagljar, Vânia Passos, Thomas Zillinger, Christine Goffinet, Daniel Sauter, Oliver T Fackler, Frank Kirchhoff
Published 2018-08-01
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