Altered Gene Expression Associated with microRNA Binding Site Polymorphisms. Bằng Urmo Võsa, Tõnu Esko, Silva Kasela, Tarmo Annilo

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Mendelian Randomization Identifies the Potential Causal Impact of Dietary Patterns on Circulating Blood Metabolites Bằng Nele Taba, Nele Taba, Hanna-Kristel Valge, Andres Metspalu, Andres Metspalu, Tõnu Esko, Tõnu Esko, James F. Wilson, James F. Wilson, Krista Fischer, Krista Fischer, Nicola Pirastu

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Within-trait heterogeneity in age group differences in personality domains and facets: implications for the development and coherence of personality traits. Bằng René Mõttus, Anu Realo, Jüri Allik, Tõnu Esko, Andres Metspalu, Wendy Johnson

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Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan Bằng Peter K. Joshi, Krista Fischer, Katharina E. Schraut, Harry Campbell, Tõnu Esko, James F. Wilson

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Genome-wide association study of obstructive sleep apnoea in the Million Veteran Program uncovers genetic heterogeneity by sexResearch in context Bằng Tamar Sofer, Nuzulul Kurniansyah, Michael Murray, Yuk-Lam Ho, Erik Abner, Tõnu Esko, Jennifer E. Huffman, Kelly Cho, Peter W.F. Wilson, Daniel J. Gottlieb, Andres Metspalu, Lili Milani, Tõnu Esko, Reedik Mägi, Mari Nelis, Georgi Hudjashov

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Predicting COVID-19 Transmission to Inform the Management of Mass Events: Model-Based Approach Bằng Claire Donnat, Freddy Bunbury, Jack Kreindler, David Liu, Filippos T Filippidis, Tonu Esko, Austen El-Osta, Matthew Harris

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Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification Bằng Kristi Läll, Maarja Lepamets, Marili Palover, Tõnu Esko, Andres Metspalu, Neeme Tõnisson, Peeter Padrik, Reedik Mägi, Krista Fischer

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Haplotype phasing and inheritance of copy number variants in nuclear families. Bằng Priit Palta, Lauris Kaplinski, Liina Nagirnaja, Andres Veidenberg, Märt Möls, Mari Nelis, Tõnu Esko, Andres Metspalu, Maris Laan, Maido Remm

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Genetic association and Mendelian randomization for hypothyroidism highlight immune molecular mechanisms Bằng Samuel Mathieu, Mewen Briend, Erik Abner, Christian Couture, Zhonglin Li, Yohan Bossé, Sébastien Thériault, Tõnu Esko, Benoit J. Arsenault, Patrick Mathieu

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Genetic determinants of plasma protein levels in the Estonian population Bằng Anette Kalnapenkis, Maarja Jõeloo, Kaido Lepik, Viktorija Kukuškina, Mart Kals, Kaur Alasoo, Estonian Biobank Research Team, Reedik Mägi, Tõnu Esko, Urmo Võsa

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Impact of the gut microbiota and associated metabolites on cardiometabolic traits, chronic diseases and human longevity: a Mendelian randomization study Bằng Eloi Gagnon, Patricia L. Mitchell, Hasanga D. Manikpurage, Erik Abner, Nele Taba, Tõnu Esko, Nooshin Ghodsian, Sébastien Thériault, Patrick Mathieu, Benoit J. Arsenault

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MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies. Bằng Toomas Haller, Liis Leitsalu, Krista Fischer, Marja-Liisa Nuotio, Tõnu Esko, Dorothea Irene Boomsma, Kirsten Ohm Kyvik, Tim D Spector, Markus Perola, Andres Metspalu

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Comorbidities confound metabolomics studies of human disease Bằng Madis Jaagura, Jaanika Kronberg, Anu Reigo, Oliver Aasmets, Tiit Nikopensius, Urmo Võsa, Lorenzo Bomba, Estonian Biobank research team, Karol Estrada, Arthur Wuster, Tõnu Esko, Elin Org

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Functional Impact and Evolution of a Novel Human Polymorphic Inversion That Disrupts a Gene and Creates a Fusion Transcript. Bằng Marta Puig, David Castellano, Lorena Pantano, Carla Giner-Delgado, David Izquierdo, Magdalena Gayà-Vidal, José Ignacio Lucas-Lledó, Tõnu Esko, Chikashi Terao, Fumihiko Matsuda, Mario Cáceres

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OTTERS: a powerful TWAS framework leveraging summary-level reference data Bằng Qile Dai, Geyu Zhou, Hongyu Zhao, Urmo Võsa, Lude Franke, Alexis Battle, Alexander Teumer, Terho Lehtimäki, Olli T. Raitakari, Tõnu Esko, eQTLGen Consortium, Michael P. Epstein, Jingjing Yang

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Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2 Bằng Luis A. Pérez-Jurado, Alejandro Cáceres, Laura Balagué-Dobón, Tonu Esko, Miguel López de Heredia, Inés Quintela, Raquel Cruz, Pablo Lapunzina, Ángel Carracedo, SCOURGE Cohort Group, Juan R. González

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Disentangling the consequences of type 2 diabetes on targeted metabolite profiles using causal inference and interaction QTL analyses. Bằng Ozvan Bocher, Archit Singh, Yue Huang, Urmo Võsa, Ene Reimann, Ana Arruda, Andrei Barysenska, Anastassia Kolde, Nigel W Rayner, Estonian Biobank research team, Tõnu Esko, Reedik Mägi, Eleftheria Zeggini

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The effect of X-linked dosage compensation on complex trait variation Bằng Julia Sidorenko, Irfahan Kassam, Kathryn E. Kemper, Jian Zeng, Luke R. Lloyd-Jones, Grant W. Montgomery, Greg Gibson, Andres Metspalu, Tonu Esko, Jian Yang, Allan F. McRae, Peter M. Visscher

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PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data. Bằng Yu-Han H Hsu, Claire Churchhouse, Tune H Pers, Josep M Mercader, Andres Metspalu, Krista Fischer, Kristen Fortney, Eric K Morgen, Clicerio Gonzalez, Maria E Gonzalez, Tonu Esko, Joel N Hirschhorn

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Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations Bằng Ville Salo, Juhani Määttä, Eeva Sliz, FinnGen, Ene Reimann, Reedik Mägi, Estonian Biobank Research Team, Kadri Reis, Abdelrahman G. Elhanas, Anu Reigo, Priit Palta, Tõnu Esko, Jaro Karppinen, Johannes Kettunen

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