Biology of secondary leukemia by Andrew M. Brunner, Timothy A. Graubert

Get full text

P758: INHIBITION OF ATR WITH CERALASERTIB (AZD6738) FOR THE TREATMENT OF PROGRESSIVE OR RELAPSED MYELODYSPLASTIC SYNDROMES AND CHRONIC MYELOMONOCYTIC LEUKEMIA: A PHASE IB/II STUDY by A. Brunner, Y. Liu, L. Mendez, J. Garcia, P. Amrein, D. Neuberg, E. Dean, S. Smith, R. Stone, A. Fathi, M. Walter, T. Graubert, M. Jacoby

Get full text

Integrated genomic analysis implicates haploinsufficiency of multiple chromosome 5q31.2 genes in de novo myelodysplastic syndromes pathogenesis. by Timothy A Graubert, Michelle A Payton, Jin Shao, Richard A Walgren, Ryan S Monahan, John L Frater, Mark A Walshauser, Mike G Martin, Yumi Kasai, Matthew J Walter

Get full text

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome by Cara Lunn Shirai, Brian S. White, Manorama Tripathi, Roberto Tapia, James N. Ley, Matthew Ndonwi, Sanghyun Kim, Jin Shao, Alexa Carver, Borja Saez, Robert S. Fulton, Catrina Fronick, Michelle O’Laughlin, Chandraiah Lagisetti, Thomas R. Webb, Timothy A. Graubert, Matthew J. Walter

Get full text

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity by van Galen, Peter, Hovestadt, Volker, Wadsworth II, Marc H., Hughes, Travis K., Griffin, Gabriel K., Battaglia, Sofia, Verga, Julia A., Stephansky, Jason, Pastika, Timothy J., Lombardi Story, Jennifer, Pinkus, Geraldine S., Pozdnyakova, Olga, Galinsky, Ilene, Stone, Richard M., Graubert, Timothy A., Shalek, Alex K., Aster, Jon C., Lane, Andrew A., Bernstein, Bradley E.

Get full text

Integrative cytogenetic and molecular studies unmask “chromosomal mimicry” in hematologic malignancies by Melissa Zhao, Scott Ryall, Samuel J. Brody, Amyah C. Harris, Kristin Cabral, Catherine Brownstein, Jaeseung C. Kim, Adam C. Smith, Paola Dal Cin, Rupa Narayan, Kristin Sikkink, Anthony Schmitt, Gabriela S. Hobbs, Amir T. Fathi, Gabriel K. Griffin, Sheila N. J. Sait, Anthony J. Iafrate, Jon C. Aster, Timothy A. Graubert, Valentina Nardi, Adrian M. Dubuc

Get full text

Clonal architecture of secondary acute myeloid leukemia defined by single-cell sequencing. by Andrew E O Hughes, Vincent Magrini, Ryan Demeter, Christopher A Miller, Robert Fulton, Lucinda L Fulton, William C Eades, Kevin Elliott, Sharon Heath, Peter Westervelt, Li Ding, Donald F Conrad, Brian S White, Jin Shao, Daniel C Link, John F DiPersio, Elaine R Mardis, Richard K Wilson, Timothy J Ley, Matthew J Walter, Timothy A Graubert

Get full text

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential by Terrence N. Wong, Christopher A. Miller, Matthew R. M. Jotte, Nusayba Bagegni, Jack D. Baty, Amy P. Schmidt, Amanda F. Cashen, Eric J. Duncavage, Nichole M. Helton, Mark Fiala, Robert S. Fulton, Sharon E. Heath, Megan Janke, Kierstin Luber, Peter Westervelt, Ravi Vij, John F. DiPersio, John S. Welch, Timothy A. Graubert, Matthew J. Walter, Timothy J. Ley, Daniel C. Link

Get full text

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia by Amir T. Fathi, Seth A. Wander, Traci M. Blonquist, Andrew M. Brunner, Philip C. Amrein, Jeffrey Supko, Nicole M. Hermance, Amity L. Manning, Hossein Sadrzadeh, Karen K. Ballen, Eyal C. Attar, Timothy A. Graubert, Gabriela Hobbs, Christelle Joseph, Ashley M. Perry, Meghan Burke, Regina Silver, Julia Foster, Meghan Bergeron, Aura Y. Ramos, Tina T. Som, Kaitlyn M. Fishman, Kristin L. McGregor, Christine Connolly, Donna S. Neuberg, Yi-Bin Chen

Get full text

SF3B1-mutant MDS as a distinct disease subtype: a proposal from the International Working Group for the Prognosis of MDS by Malcovati, L, Stevenson, K, Papaemmanuil, E, Neuberg, D, Bejar, R, Boultwood, J, Bowen, DT, Campbell, PJ, Ebert, BL, Fenaux, P, Haferlach, T, Heuser, M, Jansen, JH, Komrokji, RS, Maciejewski, JP, Walter, MJ, Fontenay, M, Garcia-Manero, G, Graubert, TA, Karsan, A, Meggendorfer, M, Pellagatti, A, Sallman, DA, Savona, MR, Sekeres, M, Steensma, DP, Tauro, S, Thol, F, Vyas, P, Van de Loosdrecht, AA, Haase, DT, Tuechler, H, Greenberg, PL, Ogawa, S, Hellstrom-Lindberg, ES, Cazzola, M

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups by Haase, D, Stevenson, KE, Neuberg, D, Maciejewski, JP, Nazha, A, Sekeres, MA, Ebert, BL, Garcia-Manero, G, Haferlach, C, Haferlach, T, Kern, W, Ogawa, S, Nagata, Y, Yoshida, K, Graubert, TA, Walter, MJ, List, AF, Komrokji, RS, Padron, E, Sallman, D, Papaemmanuil, E, Campbell, PJ, Savona, MR, Seegmiller, A, Adès, L, Fenaux, P, Shih, L-Y, Bowen, D, Groves, MJ, Tauro, S, Fontenay, M, Kosmider, O, Bar-Natan, M, Steensma, D, Stone, R, Heuser, M, Thol, F, Cazzola, M, Malcovati, L, Karsan, A, Ganster, C, Hellström-Lindberg, E, Boultwood, J, Pellagatti, A, Santini, V, Quek, L, Vyas, P, Tüchler, H, Greenberg, PL, Bejar, R, International Working Group For Mds Molecular Prognostic Committee