Early signals of vaccine driven perturbation seen in pneumococcal carriage population genomic data by Chaguza, C, Heinsbroek, E, Gladstone, R, Tafatatha, T, Alaerts, M, Peno, C, Cornick, J, Musicha, P, Bar-Zeev, N, Kamng'Ona, A, Kadioglu, A, McGee, L, Hanage, W, Breiman, R, Heyderman, R, French, N, Everett, D, Bentley, S