Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease by Xiaoting Wu, Takashi Saito, Takaomi C Saido, Anna M Barron, Christiane Ruedl

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CRISPR/dCas9-Dnmt3a-mediated targeted DNA methylation of APP rescues brain pathology in a mouse model of Alzheimer’s disease by Hanseul Park, Jaein Shin, Yunkyung Kim, Takashi Saito, Takaomi C. Saido, Jongpil Kim

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Adenosine deficiency facilitates CA1 synaptic hyperexcitability in the presymptomatic phase of a knockin mouse model of Alzheimer disease by Mattia Bonzanni, Alice Braga, Takashi Saito, Takaomi C. Saido, Giuseppina Tesco, Philip G. Haydon

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Impaired sharp-wave ripple coordination between the medial entorhinal cortex and hippocampal CA1 of knock-in model of Alzheimer’s disease by Tsukasa Funane, Heechul Jun, Stephanie Sutoko, Takaomi C. Saido, Akihiko Kandori, Kei M. Igarashi

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The senile plaque: Morphological differences in APP knock‐in mice brains by fixatives by Rikuya Yoshimura, Tomohiro Miyasaka, Satoru Funamoto, Takashi Saito, Takaomi C. Saido, Masaya Ikegawa, Nobuto Kakuda

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Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease by Ting Wang, Akira Sobue, Seiji Watanabe, Okiru Komine, Takaomi C. Saido, Takashi Saito, Koji Yamanaka

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Effects of early tooth loss on chronic stress and progression of neuropathogenesis of Alzheimer’s disease in adult Alzheimer’s model AppNL-G-F mice by Suzuko Ochi, Kumiko Yamada, Takashi Saito, Takaomi C. Saido, Mitsuo Iinuma, Kagaku Azuma, Kin-Ya Kubo

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Impairment in novelty-promoted memory via behavioral tagging and capture before apparent memory loss in a knock-in model of Alzheimer’s disease by Tabitha Broadbelt, Menekse Mutlu-Smith, Daniel Carnicero-Senabre, Takaomi C. Saido, Takashi Saito, Szu-Han Wang

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Single-cell RNA-sequencing identifies disease-associated oligodendrocytes in male APP NL-G-F and 5XFAD mice by Hanseul Park, Byounggook Cho, Hongwon Kim, Takashi Saito, Takaomi C. Saido, Kyoung-Jae Won, Jongpil Kim

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Transient sleep apnea results in long-lasting increase in β-amyloid generation and tau hyperphosphorylation by Takeru Nagayama, Sosuke Yagishita, Megumi Shibata, Akiko Furuno, Takashi Saito, Takaomi C. Saido, Shuji Wakatsuki, Toshiyuki Araki

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Amelioration of Alzheimer’s Disease by Gut-Pancreas-Liver-Brain Interaction in an App Knock-In Mouse Model by Mayumi Minamisawa, Yuma Sato, Eitarou Ishiguro, Tetsuyuki Taniai, Taiichi Sakamoto, Gota Kawai, Takashi Saito, Takaomi C. Saido

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Cerebral Aβ deposition precedes reduced cerebrospinal fluid and serum Aβ42/Aβ40 ratios in the App NL−F/NL−F knock-in mouse model of Alzheimer’s disease by Emelie Andersson, Nina Schultz, Takashi Saito, Takaomi C. Saido, Kaj Blennow, Gunnar K. Gouras, Henrik Zetterberg, Oskar Hansson

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Effects of high‐fat diet on nutrient metabolism and cognitive functions in young APPKINL‐G‐F/NL‐G‐F mice by Wei Wang, Daisuke Tanokashira, Yudai Shibayama, Ryuhei Tsuji, Megumi Maruyama, Chiemi Kuroiwa, Takashi Saito, Takaomi C. Saido, Akiko Taguchi

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T-type calcium channel enhancer SAK3 promotes dopamine and serotonin releases in the hippocampus in naive and amyloid precursor protein knock-in mice. by Shuo Wang, Yasushi Yabuki, Kazuya Matsuo, Jing Xu, Hisanao Izumi, Kenji Sakimura, Takashi Saito, Takaomi C Saido, Kohji Fukunaga

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Insoluble Aβ overexpression in an App knock-in mouse model alters microstructure and gamma oscillations in the prefrontal cortex, affecting anxiety-related behaviours by Eleftheria Pervolaraki, Stephen P. Hall, Denise Foresteire, Takashi Saito, Takaomi C. Saido, Miles A. Whittington, Colin Lever, James Dachtler

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Behavioral and neuropathological characterization over the adult lifespan of the human tau knock-in mouse by Matthew J. Benskey, Spencer Panoushek, Takashi Saito, Takashi Saito, Takaomi C. Saido, Tessa Grabinski, Nicholas M. Kanaan, Nicholas M. Kanaan

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Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation by Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Naoko Kamano, Naoto Watamura, Hiroki Sasaguri, Yuhei Takado, Yoshihiro Yoshihara, Takashi Saito, Takaomi C. Saido

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Microglia-Based Sex-Biased Neuropathology in Early-Stage Alzheimer’s Disease Model Mice and the Potential Pharmacologic Efficacy of Dioscin by Xiao Liu, Qian Zhou, Jia-He Zhang, Ke-Yong Wang, Takashi Saito, Takaomi C. Saido, Xiaoying Wang, Xiumei Gao, Kagaku Azuma

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Prenatal stress aggravates age-dependent cognitive decline, insulin signaling dysfunction, and the pro-inflammatory response in the APPNL-F/NL-F mouse model of Alzheimer's disease by Ewa Trojan, Katarzyna Curzytek, Paulina Cieślik, Joanna M. Wierońska, Johannes Graff, Władysław Lasoń, Takashi Saito, Takaomi C. Saido, Agnieszka Basta-Kaim

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Suppression of the amyloidogenic metabolism of APP and the accumulation of Aβ by alcadein α in the brain during aging by Keiko Honda, Hiroo Takahashi, Saori Hata, Ruriko Abe, Takashi Saito, Takaomi C. Saido, Hidenori Taru, Yuriko Sobu, Kanae Ando, Tohru Yamamoto, Toshiharu Suzuki

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