Emicizumab, A Bispecific Antibody to Factors IX/IXa and X/Xa, Does Not Interfere with Antithrombin or TFPI Activity In Vitro by Mariko Noguchi-Sasaki, Tetsuhiro Soeda, Atsunori Ueyama, Atsushi Muto, Michinori Hirata, Hidetomo Kitamura, Kaori Fujimoto-Ouchi, Yoshiki Kawabe, Keiji Nogami, Midori Shima, Takehisa Kitazawa

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Determination of starting dose of the T cell-redirecting bispecific antibody ERY974 targeting glypican-3 in first-in-human clinical trial by Shun-ichiro Komatsu, Yoko Kayukawa, Yoko Miyazaki, Akihisa Kaneko, Hisashi Ikegami, Takahiro Ishiguro, Mikiko Nakamura, Werner Frings, Natsuki Ono, Kiyoaki Sakata, Toshihiko Fujii, Shohei Kishishita, Takehisa Kitazawa, Mika Endo, Yuji Sano

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Antibody engineering to generate SKY59, a long-acting anti-C5 recycling antibody. by Zenjiro Sampei, Kenta Haraya, Tatsuhiko Tachibana, Taku Fukuzawa, Meiri Shida-Kawazoe, Siok Wan Gan, Yuichiro Shimizu, Yoshinao Ruike, Shu Feng, Taichi Kuramochi, Masaru Muraoka, Takehisa Kitazawa, Yoshiki Kawabe, Tomoyuki Igawa, Kunihiro Hattori, Junichi Nezu

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1172 SAIL66, a next generation of T cell engager targeting CLDN6, potentiates efficacy by Hiroyuki Aburatani, Mika Kamata-Sakurai, Shinya Ishii, Takayuki Kamikawa, Naoki Kimura, Masaru Muraoka, Kenji Taniguchi, Ryo Uchikawa, Moe Yoshimoto, Momoko Okuda-Miura, Sho Akai, Tatsushi Kodama, Hirofumi Sakumoto, Shigeto Kawai, Mei Shimada, Takehisa Kitazawa, Tomoyuki Igawa

Efficient production of bispecific antibody by FAST-IgTM and its application to NXT007 for the treatment of hemophilia A by Hikaru Koga, Takashi Yamano, Juan Betancur, Satoko Nagatomo, Yousuke Ikeda, Kazuki Yamaguchi, Yoshiaki Nabuchi, Kazuki Sato, Yuri Teranishi-Ikawa, Motohiko Sato, Hiroyuki Hirayama, Akira Hayasaka, Takuya Torizawa, Kenta Haraya, Zenjiro Sampei, Hirotake Shiraiwa, Takehisa Kitazawa, Tomoyuki Igawa, Taichi Kuramochi

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Combination of T cell-redirecting bispecific antibody ERY974 and chemotherapy reciprocally enhances efficacy against non-inflamed tumours by Yuji Sano, Yumiko Azuma, Toshiaki Tsunenari, Yoko Kayukawa, Junko Shinozuka, Etsuko Fujii, Jun Amano, Yukari Nishito, Toru Maruyama, Yasuko Kinoshita, Yuichiro Sakamoto, Ayae Yoshida, Yoko Miyazaki, Yuta Sato, Chifumi Teramoto-Seida, Takahiro Ishiguro, Takayoshi Tanaka, Takehisa Kitazawa, Mika Endo

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Identification and multidimensional optimization of an asymmetric bispecific IgG antibody mimicking the function of factor VIII cofactor activity. by Zenjiro Sampei, Tomoyuki Igawa, Tetsuhiro Soeda, Yukiko Okuyama-Nishida, Chifumi Moriyama, Tetsuya Wakabayashi, Eriko Tanaka, Atsushi Muto, Tetsuo Kojima, Takehisa Kitazawa, Kazutaka Yoshihashi, Aya Harada, Miho Funaki, Kenta Haraya, Tatsuhiko Tachibana, Sachiyo Suzuki, Keiko Esaki, Yoshiaki Nabuchi, Kunihiro Hattori

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Novel myostatin-specific antibody enhances muscle strength in muscle disease models by Hiroyasu Muramatsu, Taichi Kuramochi, Hitoshi Katada, Atsunori Ueyama, Yoshinao Ruike, Ken Ohmine, Meiri Shida-Kawazoe, Rie Miyano-Nishizawa, Yuichiro Shimizu, Momoko Okuda, Yuji Hori, Madoka Hayashi, Kenta Haraya, Nobuhiro Ban, Tatsuya Nonaka, Masaki Honda, Hidetomo Kitamura, Kunihiro Hattori, Takehisa Kitazawa, Tomoyuki Igawa, Yoshiki Kawabe, Junichi Nezu

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Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease by Yuu Okura, Yuri Ikawa-Teranishi, Akihiko Mizoroki, Noriyuki Takahashi, Takashi Tsushima, Machiko Irie, Zulkarnain Harfuddin, Momoko Miura-Okuda, Shunsuke Ito, Genki Nakamura, Hiroaki Takesue, Yui Ozono, Masamichi Nishihara, Kenta Yamada, Siok Wan Gan, Akira Hayasaka, Shinya Ishii, Tetsuya Wakabayashi, Masaru Muraoka, Nishiki Nagaya, Hiroshi Hino, Takayuki Nemoto, Taichi Kuramochi, Takuya Torizawa, Hideaki Shimada, Takehisa Kitazawa, Makoto Okazaki, Junichi Nezu, Ludvig M. Sollid, Tomoyuki Igawa

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Long lasting neutralization of C5 by SKY59, a novel recycling antibody, is a potential therapy for complement-mediated diseases by Taku Fukuzawa, Zenjiro Sampei, Kenta Haraya, Yoshinao Ruike, Meiri Shida-Kawazoe, Yuichiro Shimizu, Siok Wan Gan, Machiko Irie, Yoshinori Tsuboi, Hitoshi Tai, Tetsushi Sakiyama, Akihisa Sakamoto, Shinya Ishii, Atsuhiko Maeda, Yuki Iwayanagi, Norihito Shibahara, Mitsuko Shibuya, Genki Nakamura, Takeru Nambu, Akira Hayasaka, Futa Mimoto, Yuu Okura, Yuji Hori, Kiyoshi Habu, Manabu Wada, Takaaki Miura, Tatsuhiko Tachibana, Kiyofumi Honda, Hiroyuki Tsunoda, Takehisa Kitazawa, Yoshiki Kawabe, Tomoyuki Igawa, Kunihiro Hattori, Junichi Nezu

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