Mechanistic insights and the clinical prospects of targeted therapies for glioblastoma: a comprehensive review by Yating Shen, Dexter Kai Hao Thng, Andrea Li Ann Wong, Tan Boon Toh

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JAK/STAT signaling in hepatocellular carcinoma by Justin Jit Hin Tang, Dexter Kai Hao Thng, Jhin Jieh Lim, Tan Boon Toh

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Biomarkers for immune checkpoint inhibition in sarcomas – are we close to clinical implementation? by Chin Sern Yiong, Tzu Ping Lin, Vivian Yujing Lim, Tan Boon Toh, Valerie Shiwen Yang

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Rational drug combination design in patient-derived avatars reveals effective inhibition of hepatocellular carcinoma with proteasome and CDK inhibitors by Jhin Jieh Lim, Lissa Hooi, Yock Young Dan, Glenn K. Bonney, Lei Zhou, Pierce K.-H. Chow, Cheng Ean Chee, Tan Boon Toh, Edward K.-H. Chow

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Splice‐switch oligonucleotide‐based combinatorial platform prioritizes synthetic lethal targets CHK1 and BRD4 against MYC‐driven hepatocellular carcinoma by Dexter Kai Hao Thng, Tan Boon Toh, Paolo Pigini, Lissa Hooi, Yock Young Dan, Pierce Kah‐Hoe Chow, Glenn Kunnath Bonney, Masturah Bte Mohd Abdul Rashid, Ernesto Guccione, Dave Keng Boon Wee, Edward Kai‐Hua Chow

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Targeted Inhibition of Purine Metabolism Is Effective in Suppressing Hepatocellular Carcinoma Progression by Yong Chun Chong, Tan Boon Toh, Zhiling Chan, Quy Xiao Xuan Lin, Dexter Kai Hao Thng, Lissa Hooi, Zhaobing Ding, Timothy Shuen, Han Chong Toh, Yock Young Dan, Glenn Kunnath Bonney, Lei Zhou, Pierce Chow, Yulan Wang, Touati Benoukraf, Edward Kai‐Hua Chow, Weiping Han

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A functional personalised oncology approach against metastatic colorectal cancer in matched patient derived organoids by Dexter Kai Hao Thng, Lissa Hooi, Bei En Siew, Kai-Yin Lee, Ian Jse-Wei Tan, Bettina Lieske, Norman Sihan Lin, Alfred Wei Chieh Kow, Shi Wang, Masturah Bte Mohd Abdul Rashid, Chermaine Ang, Jasmin Jia Min Koh, Tan Boon Toh, Ker-Kan Tan, Edward Kai-Hua Chow

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Evaluation of ex vivo drug combination optimization platform in recurrent high grade astrocytic glioma: An interventional, non-randomized, open-label trial protocol. by Tan Boon Toh, Dexter Kai Hao Thng, Nagarjun Bolem, Balamurugan A Vellayappan, Bryce Wei Quan Tan, Yating Shen, Sou Yen Soon, Yvonne Li En Ang, Nivedh Dinesh, Kejia Teo, Vincent Diong Weng Nga, Shiong Wen Low, Pek Lan Khong, Edward Kai-Hua Chow, Dean Ho, Tseng Tsai Yeo, Andrea Li Ann Wong

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Histone‐lysine N‐methyltransferase EHMT2 (G9a) inhibition mitigates tumorigenicity in Myc‐driven liver cancer by Dexter Kai Hao Thng, Lissa Hooi, Clarissa Chin Min Toh, Jhin Jieh Lim, Deepa Rajagopalan, Imran Qamar Charles Syariff, Zher Min Tan, Masturah Bte Mohd Abdul Rashid, Lei Zhou, Alfred Wei Chieh Kow, Glenn Kunnath Bonney, Brian Kim Poh Goh, Juinn Huar Kam, Sudhakar Jha, Yock Young Dan, Pierce Kah Hoe Chow, Tan Boon Toh, Edward Kai‐Hua Chow

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METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity by Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong

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Author Correction: METTL8 links mt-tRNA m3C modification to the HIF1α/RTK/Akt axis to sustain GBM stemness and tumorigenicity by Bernice Woon Li Lee, You Heng Chuah, Jeehyun Yoon, Oleg V. Grinchuk, Yajing Liang, Jayshree L. Hirpara, Yating Shen, Loo Chien Wang, Yan Ting Lim, Tianyun Zhao, Radoslaw M. Sobota, Tseng Tsai Yeo, Andrea Li Ann Wong, Kejia Teo, Vincent Diong Weng Nga, Bryce Wei Quan Tan, Toshio Suda, Tan Boon Toh, Shazib Pervaiz, Zhewang Lin, Derrick Sek Tong Ong

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