Tania A. Baker

Tania A. Baker is an American biochemist who is a Professor of Biology at the Massachusetts Institute of Technology and formally the head of the Department of Biology. She earned her B.S. in Biochemistry from University of Wisconsin–Madison and her Ph.D. in Biochemistry from Stanford University under the guidance of Arthur Kornberg. She joined the MIT faculty in 1992 and her research is focused on the mechanisms and regulation of DNA transposition and protein chaperones. She is a member of the National Academy of Sciences, fellow of the American Academy of Arts and Sciences, and has been a Howard Hughes Medical Institute (HHMI) investigator since 1994. Provided by Wikipedia
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  1. 1
    The Non-dominant AAA+ Ring in the ClpAP Protease Functions as an Anti-stalling Motor to Accelerate Protein Unfolding and Translocation

    The Non-dominant AAA+ Ring in the ClpAP Protease Functions as an Anti-stalling Motor to Accelerate Protein Unfolding and Translocation by Hema Chandra Kotamarthi, Robert T. Sauer, Tania A. Baker

    Published 2020-02-01
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    Article
  2. 2
    Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding

    Interactions between a subset of substrate side chains and AAA+ motor pore loops determine grip during protein unfolding by Tristan A Bell, Tania A Baker, Robert T Sauer

    Published 2019-06-01
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    Article
  3. 3
    Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding

    Mitochondrial ClpX activates an essential biosynthetic enzyme through partial unfolding by Julia R Kardon, Jamie A Moroco, John R Engen, Tania A Baker

    Published 2020-02-01
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  4. 4
    Regulation of Antimycin Biosynthesis Is Controlled by the ClpXP Protease

    Regulation of Antimycin Biosynthesis Is Controlled by the ClpXP Protease by Bohdan Bilyk, Sora Kim, Asif Fazal, Tania A. Baker, Ryan F. Seipke

    Published 2020-04-01
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  5. 5
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates

    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates by Xue Fei, Tristan A Bell, Sarah R Barkow, Tania A Baker, Robert T Sauer

    Published 2020-10-01
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  6. 6
    ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP

    ClpAP proteolysis does not require rotation of the ClpA unfoldase relative to ClpP by Sora Kim, Kristin L Zuromski, Tristan A Bell, Robert T Sauer, Tania A Baker

    Published 2020-12-01
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  7. 7
    NOA1, a novel ClpXP substrate, takes an unexpected nuclear detour prior to mitochondrial import.

    NOA1, a novel ClpXP substrate, takes an unexpected nuclear detour prior to mitochondrial import. by Natalie Al-Furoukh, Julia R Kardon, Marcus Krüger, Marten Szibor, Tania A Baker, Thomas Braun

    Published 2014-01-01
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  8. 8
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate

    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate by Xue Fei, Tristan A Bell, Simon Jenni, Benjamin M Stinson, Tania A Baker, Stephen C Harrison, Robert T Sauer

    Published 2020-02-01
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  9. 9
    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease

    Lon degrades stable substrates slowly but with enhanced processivity, redefining the attributes of a successful AAA+ protease by Meghann R. Kasal, Hema Chandra Kotamarthi, Madeline M. Johnson, Hannah M. Stephens, Matthew J. Lang, Robert T. Sauer, Tania A. Baker

    Published 2023-09-01
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  10. 10
    A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation

    A closed translocation channel in the substrate-free AAA+ ClpXP protease diminishes rogue degradation by Alireza Ghanbarpour, Steven E. Cohen, Xue Fei, Laurel F. Kinman, Tristan A. Bell, Jia Jia Zhang, Tania A. Baker, Joseph H. Davis, Robert T. Sauer

    Published 2023-11-01
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  11. 11
    Substrate specificity of [alpha]-proteobacterial N-end rule adaptors

    Substrate specificity of [alpha]-proteobacterial N-end rule adaptors by Stein, Benjamin J. (Benjamin Joseph)

    Published 2016
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  12. 12
    Mechanisms of CipS reprogramming of the AAA+ protease CipAP

    Mechanisms of CipS reprogramming of the AAA+ protease CipAP by Torres-Delgado, Amaris

    Published 2016
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  13. 13
    Functions of alternative ClpP subunits in Pseudomonas aeruginosa

    Functions of alternative ClpP subunits in Pseudomonas aeruginosa by Mawla, Gina D. (Gina Danielle), Ph.D., Massachusetts Institute of Technology

    Published 2020
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  14. 14
    Substrate selection by the ClpXP protease : a tail of destruction

    Substrate selection by the ClpXP protease : a tail of destruction by Flynn, Julia M., 1976-

    Published 2005
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  15. 15
    Mechanism and consequences of Mu transpososome remodeling by the ClpX chaperone

    Mechanism and consequences of Mu transpososome remodeling by the ClpX chaperone by Burton, Briana M. (Briana Marie), 1977-

    Published 2005
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  16. 16
    Dynamics of protein-DNA interactions in a Mu transpososome

    Dynamics of protein-DNA interactions in a Mu transpososome by Goldhaber-Gordon, Ilana Michal, 1972-

    Published 2006
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  17. 17
    The role of ClpXP-mediated proteolysis in resculpting the proteome after DNA damage

    The role of ClpXP-mediated proteolysis in resculpting the proteome after DNA damage by Neher, Saskia B. (Saskia Byerly)

    Published 2006
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  18. 18
    Dissecting the steps of substrate processing by the energy-dependent protease ClpXP

    Dissecting the steps of substrate processing by the energy-dependent protease ClpXP by Siddiqui, Samia M. (Siddiqui Mohammed), 1977-

    Published 2006
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  19. 19
    Binding with intent to destroy : RssB adaptor function in Clp-XP-mediated proteolysis of sigmaS

    Binding with intent to destroy : RssB adaptor function in Clp-XP-mediated proteolysis of sigmaS by Ebrahim, Shamsah

    Published 2008
    Other Authors: “…Tania A. Baker.…”
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    Thesis
  20. 20
    Regulation of Mu transposition via communication between the transposase and Mu-encoded accessory protein

    Regulation of Mu transposition via communication between the transposase and Mu-encoded accessory protein by Schweidenback, Caterina Taiani Hill

    Published 2008
    Other Authors: “…Tania A. Baker.…”
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    Thesis

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