Tanja Kortemme

Tanja Kortemme is a bioengineering professor at University of California, San Francisco. She has been recognized for outstanding contributions in computational protein design, including energy functions, sampling algorithms, and molecules to rewire cellular control circuits. She was an inaugural Chan Zuckerberg Biohub investigator and was inducted into American Institute for Medical and Biological Engineering College of Fellows. Provided by Wikipedia
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  1. 1
    An integrative approach to protein sequence design through multiobjective optimization.

    An integrative approach to protein sequence design through multiobjective optimization. by Lu Hong, Tanja Kortemme

    Published 2024-07-01
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  2. 2
    Computational protein design quantifies structural constraints on amino acid covariation.

    Computational protein design quantifies structural constraints on amino acid covariation. by Noah Ollikainen, Tanja Kortemme

    Published 2013-01-01
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  3. 3
    Complex topology rather than complex membership is a determinant of protein dosage sensitivity

    Complex topology rather than complex membership is a determinant of protein dosage sensitivity by Richard Oberdorf, Tanja Kortemme

    Published 2009-03-01
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  4. 4
    Design of multi-specificity in protein interfaces.

    Design of multi-specificity in protein interfaces. by Elisabeth L Humphris, Tanja Kortemme

    Published 2007-08-01
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  5. 5
    New computational protein design methods for de novo small molecule binding sites.

    New computational protein design methods for de novo small molecule binding sites. by James E Lucas, Tanja Kortemme

    Published 2020-10-01
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  6. 6
    Predicting the tolerated sequences for proteins and protein interfaces using RosettaBackrub flexible backbone design.

    Predicting the tolerated sequences for proteins and protein interfaces using RosettaBackrub flexible backbone design. by Colin A Smith, Tanja Kortemme

    Published 2011-01-01
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  7. 7
    Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity.

    Coupling Protein Side-Chain and Backbone Flexibility Improves the Re-design of Protein-Ligand Specificity. by Noah Ollikainen, René M de Jong, Tanja Kortemme

    Published 2015-01-01
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  8. 8
    Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme

    Altered expression of a quality control protease in E. coli reshapes the in vivo mutational landscape of a model enzyme by Samuel Thompson, Yang Zhang, Christine Ingle, Kimberly A Reynolds, Tanja Kortemme

    Published 2020-07-01
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  9. 9
    Prediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein design.

    Prediction of mutational tolerance in HIV-1 protease and reverse transcriptase using flexible backbone protein design. by Elisabeth Humphris-Narayanan, Eyal Akiva, Rocco Varela, Shane Ó Conchúir, Tanja Kortemme

    Published 2012-01-01
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  10. 10
    A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family.

    A correspondence between solution-state dynamics of an individual protein and the sequence and conformational diversity of its family. by Gregory D Friedland, Nils-Alexander Lakomek, Christian Griesinger, Jens Meiler, Tanja Kortemme

    Published 2009-05-01
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  11. 11
    Author Correction: Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor

    Author Correction: Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor by Anum Glasgow, Helen T. Hobbs, Zion R. Perry, Malcolm L. Wells, Susan Marqusee, Tanja Kortemme

    Published 2023-07-01
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  12. 12
    Amino-acid site variability among natural and designed proteins

    Amino-acid site variability among natural and designed proteins by Eleisha L. Jackson, Noah Ollikainen, Arthur W. Covert III, Tanja Kortemme, Claus O. Wilke

    Published 2013-11-01
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  13. 13
    Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor

    Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor by Anum Glasgow, Helen T. Hobbs, Zion R. Perry, Malcolm L. Wells, Susan Marqusee, Tanja Kortemme

    Published 2023-03-01
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  14. 14
    A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design.

    A Web Resource for Standardized Benchmark Datasets, Metrics, and Rosetta Protocols for Macromolecular Modeling and Design. by Shane Ó Conchúir, Kyle A Barlow, Roland A Pache, Noah Ollikainen, Kale Kundert, Matthew J O'Meara, Colin A Smith, Tanja Kortemme

    Published 2015-01-01
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  15. 15
    Deconstruction of the Ras switching cycle through saturation mutagenesis

    Deconstruction of the Ras switching cycle through saturation mutagenesis by Pradeep Bandaru, Neel H Shah, Moitrayee Bhattacharyya, John P Barton, Yasushi Kondo, Joshua C Cofsky, Christine L Gee, Arup K Chakraborty, Tanja Kortemme, Rama Ranganathan, John Kuriyan

    Published 2017-07-01
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  16. 16
    Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads

    Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads by Huy Quoc Nguyen, Jagoree Roy, Björn Harink, Nikhil P Damle, Naomi R Latorraca, Brian C Baxter, Kara Brower, Scott A Longwell, Tanja Kortemme, Kurt S Thorn, Martha S Cyert, Polly Morrell Fordyce

    Published 2019-07-01
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  17. 17
    Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs

    Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs by Kale Kundert, James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin M. Heineike, Christina M. Fitzsimmons, Benjamin L. Oakes, Jiuxin Qu, Neha Prasad, Oren S. Rosenberg, David F. Savage, Hana El-Samad, Jennifer A. Doudna, Tanja Kortemme

    Published 2019-05-01
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  18. 18
    Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE).

    Serverification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE). by Sergey Lyskov, Fang-Chieh Chou, Shane Ó Conchúir, Bryan S Der, Kevin Drew, Daisuke Kuroda, Jianqing Xu, Brian D Weitzner, P Douglas Renfrew, Parin Sripakdeevong, Benjamin Borgo, James J Havranek, Brian Kuhlman, Tanja Kortemme, Richard Bonneau, Jeffrey J Gray, Rhiju Das

    Published 2013-01-01
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  19. 19
    Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting

    Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting by David Mavor, Kyle Barlow, Samuel Thompson, Benjamin A Barad, Alain R Bonny, Clinton L Cario, Garrett Gaskins, Zairan Liu, Laura Deming, Seth D Axen, Elena Caceres, Weilin Chen, Adolfo Cuesta, Rachel E Gate, Evan M Green, Kaitlin R Hulce, Weiyue Ji, Lillian R Kenner, Bruk Mensa, Leanna S Morinishi, Steven M Moss, Marco Mravic, Ryan K Muir, Stefan Niekamp, Chimno I Nnadi, Eugene Palovcak, Erin M Poss, Tyler D Ross, Eugenia C Salcedo, Stephanie K See, Meena Subramaniam, Allison W Wong, Jennifer Li, Kurt S Thorn, Shane Ó Conchúir, Benjamin P Roscoe, Eric D Chow, Joseph L DeRisi, Tanja Kortemme, Daniel N Bolon, James S Fraser

    Published 2016-04-01
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  20. 20
    Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks

    Ensuring scientific reproducibility in bio-macromolecular modeling via extensive, automated benchmarks by Julia Koehler Leman, Sergey Lyskov, Steven M. Lewis, Jared Adolf-Bryfogle, Rebecca F. Alford, Kyle Barlow, Ziv Ben-Aharon, Daniel Farrell, Jason Fell, William A. Hansen, Ameya Harmalkar, Jeliazko Jeliazkov, Georg Kuenze, Justyna D. Krys, Ajasja Ljubetič, Amanda L. Loshbaugh, Jack Maguire, Rocco Moretti, Vikram Khipple Mulligan, Morgan L. Nance, Phuong T. Nguyen, Shane Ó Conchúir, Shourya S. Roy Burman, Rituparna Samanta, Shannon T. Smith, Frank Teets, Johanna K. S. Tiemann, Andrew Watkins, Hope Woods, Brahm J. Yachnin, Christopher D. Bahl, Chris Bailey-Kellogg, David Baker, Rhiju Das, Frank DiMaio, Sagar D. Khare, Tanja Kortemme, Jason W. Labonte, Kresten Lindorff-Larsen, Jens Meiler, William Schief, Ora Schueler-Furman, Justin B. Siegel, Amelie Stein, Vladimir Yarov-Yarovoy, Brian Kuhlman, Andrew Leaver-Fay, Dominik Gront, Jeffrey J. Gray, Richard Bonneau

    Published 2021-11-01
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