Target-specific compound selectivity for multi-target drug discovery and repurposing by Tianduanyi Wang, Tianduanyi Wang, Otto I. Pulkkinen, Otto I. Pulkkinen, Otto I. Pulkkinen, Tero Aittokallio, Tero Aittokallio, Tero Aittokallio, Tero Aittokallio, Tero Aittokallio

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Glioblastoma and the search for non-hypothesis driven combination therapeutics in academia by Timothy Johanssen, Laura McVeigh, Sara Erridge, Geoffrey Higgins, Joelle Straehla, Margaret Frame, Tero Aittokallio, Tero Aittokallio, Tero Aittokallio, Neil O. Carragher, Daniel Ebner, Daniel Ebner

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Tissue-specific identification of multi-omics features for pan-cancer drug response prediction by Zhi Zhao, Shixiong Wang, Manuela Zucknick, Tero Aittokallio

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Improved detection of differentially represented DNA barcodes for high‐throughput clonal phenomics by Yevhen Akimov, Daria Bulanova, Sanna Timonen, Krister Wennerberg, Tero Aittokallio

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Predicting quantitative genetic interactions by means of sequential matrix approximation. by Aki P Järvinen, Jukka Hiissa, Laura L Elo, Tero Aittokallio

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OSCAR: Optimal subset cardinality regression using the L0-pseudonorm with applications to prognostic modelling of prostate cancer. by Anni S Halkola, Kaisa Joki, Tuomas Mirtti, Marko M Mäkelä, Tero Aittokallio, Teemu D Laajala

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Quantitative subcellular proteome and secretome profiling of influenza A virus-infected human primary macrophages. by Niina Lietzén, Tiina Ohman, Johanna Rintahaka, Ilkka Julkunen, Tero Aittokallio, Sampsa Matikainen, Tuula A Nyman

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Systematic review of computational methods for drug combination prediction by Weikaixin Kong, Gianmarco Midena, Yingjia Chen, Paschalis Athanasiadis, Tianduanyi Wang, Juho Rousu, Liye He, Tero Aittokallio

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Computational-experimental approach to drug-target interaction mapping: A case study on kinase inhibitors. by Anna Cichonska, Balaguru Ravikumar, Elina Parri, Sanna Timonen, Tapio Pahikkala, Antti Airola, Krister Wennerberg, Juho Rousu, Tero Aittokallio

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MicroRNA‐135b regulates ERα, AR and HIF1AN and affects breast and prostate cancer cell growth by Anna Aakula, Suvi-Katri Leivonen, Petteri Hintsanen, Tero Aittokallio, Yvonne Ceder, Anne-Lise Børresen-Dale, Merja Perälä, Päivi Östling, Olli Kallioniemi

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Novel Lignan and stilbenoid mixture shows anticarcinogenic efficacy in preclinical PC-3M-luc2 prostate cancer model. by Emrah Yatkin, Lauri Polari, Teemu D Laajala, Annika Smeds, Christer Eckerman, Bjarne Holmbom, Niina M Saarinen, Tero Aittokallio, Sari I Mäkelä

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Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells by Paschalis Athanasiadis, Balaguru Ravikumar, Richard J.R. Elliott, John C. Dawson, Neil O. Carragher, Paul A. Clemons, Timothy Johanssen, Daniel Ebner, Tero Aittokallio

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Multi‐modal meta‐analysis of cancer cell line omics profiles identifies ECHDC1 as a novel breast tumor suppressor by Alok Jaiswal, Prson Gautam, Elina A Pietilä, Sanna Timonen, Nora Nordström, Yevhen Akimov, Nina Sipari, Ziaurrehman Tanoli, Thomas Fleischer, Kaisa Lehti, Krister Wennerberg, Tero Aittokallio

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Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells by Oxana V. Denisova, Joni Merisaari, Amanpreet Kaur, Laxman Yetukuri, Mikael Jumppanen, Carina von Schantz-Fant, Michael Ohlmeyer, Krister Wennerberg, Tero Aittokallio, Mikko Taipale, Jukka Westermarck

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Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation by Maja Šolman, Alessio Ligabue, Olga Blaževitš, Alok Jaiswal, Yong Zhou, Hong Liang, Benoit Lectez, Kari Kopra, Camilo Guzmán, Harri Härmä, John F Hancock, Tero Aittokallio, Daniel Abankwa

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P1228: GENOME-WIDE CRISPR-CAS9 SCREENING IDENTIFIES THERAPEUTIC TARGETS FOR MATURE T-CELL MALIGNANCIES by Sanna Timonen, Vanessa Rebecca Gasparini, Ella Piekkari, Olli Dufva, Shady Awad, Yevhen Akimov, Jana von Jan, Till Braun, Aleksandr Ianevski, Matti Kankainen, Jay Klievink, Marco Herling, Tero Aittokallio, Satu Mustjoki

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Combinations of Host- and Virus-Targeting Antiviral Drugs Confer Synergistic Suppression of SARS-CoV-2 by Jessica Wagoner, Shawn Herring, Tien-Ying Hsiang, Aleksandr Ianevski, Scott B. Biering, Shuang Xu, Markus Hoffmann, Stefan Pöhlmann, Michael Gale, Tero Aittokallio, Joshua T. Schiffer, Judith M. White, Stephen J. Polyak

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PP2A‐based triple‐strike therapy overcomes mitochondrial apoptosis resistance in brain cancer cells by Oxana V. Denisova, Joni Merisaari, Riikka Huhtaniemi, Xi Qiao, Laxman Yetukuri, Mikael Jumppanen, Amanpreet Kaur, Mirva Pääkkönen, Сarina vonSchantz‐Fant, Michael Ohlmeyer, Krister Wennerberg, Otto Kauko, Raphael Koch, Tero Aittokallio, Mikko Taipale, Jukka Westermarck

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Single-cell transcriptomes identify patient-tailored therapies for selective co-inhibition of cancer clones by Aleksandr Ianevski, Kristen Nader, Kyriaki Driva, Wojciech Senkowski, Daria Bulanova, Lidia Moyano-Galceran, Tanja Ruokoranta, Heikki Kuusanmäki, Nemo Ikonen, Philipp Sergeev, Markus Vähä-Koskela, Anil K. Giri, Anna Vähärautio, Mika Kontro, Kimmo Porkka, Esa Pitkänen, Caroline A. Heckman, Krister Wennerberg, Tero Aittokallio

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Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia by Brian S. White, Suleiman A. Khan, Mike J. Mason, Muhammad Ammad-ud-din, Swapnil Potdar, Disha Malani, Heikki Kuusanmäki, Brian J. Druker, Caroline Heckman, Olli Kallioniemi, Stephen E. Kurtz, Kimmo Porkka, Cristina E. Tognon, Jeffrey W. Tyner, Tero Aittokallio, Krister Wennerberg, Justin Guinney

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