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CRISPR Loss-of-Function Screen Identifies the Hippo Signaling Pathway as the Mediator of Regorafenib Efficacy in Hepatocellular Carcinoma by Shigeki Suemura, Takahiro Kodama, Yuta Myojin, Ryoko Yamada, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Published 2019-09-01
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Serum Mac-2 Binding Protein Levels Associate with Metabolic Parameters and Predict Liver Fibrosis Progression in Subjects with Fatty Liver Disease: A 7-Year Longitudinal Study by Yoshihiro Kamada, Koichi Morishita, Masahiro Koseki, Mayu Nishida, Tatsuya Asuka, Yukiko Naito, Makoto Yamada, Shinji Takamatsu, Yasushi Sakata, Tetsuo Takehara, Eiji Miyoshi
Published 2020-06-01
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A novel role for Helicobacter pylori cytotoxin-associated gene A in negative regulation of autophagy in human gastric cells by Akihiko Sakatani, Yoshito Hayashi, Hirotsugu Saiki, Minoru Kato, Ryotaro Uema, Takanori Inoue, Keiichi Kimura, Shunsuke Yoshii, Yoshiki Tsujii, Shinichiro Shinzaki, Hideki Iijima, Tetsuo Takehara
Published 2023-09-01
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CEACAM1 Is Associated With the Suppression of Natural Killer Cell Function in Patients With Chronic Hepatitis C by Takahiro Suda, Tomohide Tatsumi, Akira Nishio, Tadashi Kegasawa, Teppei Yoshioka, Ryoko Yamada, Kunimaro Furuta, Takahiro Kodama, Minoru Shigekawa, Hayato Hikita, Ryotaro Sakamori, Takasuke Fukuhara, Yoshiharu Matsuura, Tetsuo Takehara
Published 2018-10-01
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Activation of p53 After Irradiation Impairs the Regenerative Capacity of the Mouse Liver by Makiko Urabe, Hayato Hikita, Yoshinobu Saito, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuta Myojin, Akira Doi, Katsuhiko Sato, Sadatsugu Sakane, Yuki Makino, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Published 2022-02-01
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White Adipose Tissue Autophagy and Adipose-Liver Crosstalk Exacerbate Nonalcoholic Fatty Liver Disease in MiceSummary by Sadatsugu Sakane, Hayato Hikita, Kumiko Shirai, Yuta Myojin, Youichi Sasaki, Shinnosuke Kudo, Kenji Fukumoto, Naoki Mizutani, Yuki Tahata, Yuki Makino, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Published 2021-01-01
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Seasonal variations in gut microbiota and disease course in patients with inflammatory bowel disease. by Mizuki Tani, Shinichiro Shinzaki, Akiko Asakura, Taku Tashiro, Takahiro Amano, Yuriko Otake-Kasamoto, Takeo Yoshihara, Shunsuke Yoshii, Yoshiki Tsujii, Yoshito Hayashi, Takahiro Inoue, Daisuke Motooka, Shota Nakamura, Hideki Iijima, Tetsuo Takehara
Published 2023-01-01
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Capsid Allosteric Modulators Enhance the Innate Immune Response in Hepatitis B Virus–Infected Hepatocytes During Interferon Administration by Keisuke Fukutomi, Hayato Hikita, Kazuhiro Murai, Tasuku Nakabori, Akiyoshi Shimoda, Makoto Fukuoka, Takuo Yamai, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Ryoko Yamada, Takahiro Kodama, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Published 2022-02-01
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Initial drainage‐related prognostic factors for perihilar cholangiocarcinoma: A single‐center retrospective study by Katsuhiko Sato, Minoru Shigekawa, Kazuhiro Kozumi, Junya Okabe, Yu Sato, Takeshi Tamura, Teppei Yoshioka, Ryotaro Sakamori, Yoshifumi Iwagami, Daisaku Yamada, Yoshito Tomimaru, Takehiro Noda, Hidenori Takahashi, Shogo Kobayashi, Hidetoshi Eguchi, Tomohide Tatsumi, Tetsuo Takehara
Published 2023-04-01
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Regnase-1 downregulation promotes pancreatic cancer through myeloid-derived suppressor cell-mediated evasion of anticancer immunity by Junya Okabe, Takahiro Kodama, Yu Sato, Satoshi Shigeno, Takayuki Matsumae, Kazuma Daiku, Katsuhiko Sato, Teppei Yoshioka, Minoru Shigekawa, Masaya Higashiguchi, Shogo Kobayashi, Hayato Hikita, Tomohide Tatsumi, Toru Okamoto, Takashi Satoh, Hidetoshi Eguchi, Shizuo Akira, Tetsuo Takehara
Published 2023-10-01
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STAT3 is Activated by CTGF-mediated Tumor-stroma Cross Talk to Promote HCC ProgressionSummary by Yuki Makino, Hayato Hikita, Seiya Kato, Masaya Sugiyama, Minoru Shigekawa, Tatsuya Sakamoto, Yoichi Sasaki, Kazuhiro Murai, Sadatsugu Sakane, Takahiro Kodama, Ryotaro Sakamori, Shogo Kobayashi, Hidetoshi Eguchi, Nobuyuki Takemura, Norihiro Kokudo, Hideki Yokoi, Masashi Mukoyama, Tomohide Tatsumi, Tetsuo Takehara
Published 2023-01-01
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Inhibition of nonhomologous end joining‐mediated DNA repair enhances anti‐HBV CRISPR therapy by Kazuhiro Murai, Takahiro Kodama, Hayato Hikita, Akiyoshi Shimoda, Makoto Fukuoka, Keisuke Fukutomi, Satoshi Shigeno, Yuto Shiode, Daisuke Motooka, Yuichiro Higuchi, Kei Miyakawa, Hiroshi Suemizu, Akihide Ryo, Yuki Tahata, Yuki Makino, Ryoko Yamada, Ryotaro Sakamori, Tomohide Tatsumi, Tetsuo Takehara
Published 2022-09-01
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Interleukin-6 Is a Circulating Prognostic Biomarker for Hepatocellular Carcinoma Patients Treated with Combined Immunotherapy by Yuta Myojin, Takahiro Kodama, Ryotaro Sakamori, Kazuki Maesaka, Takayuki Matsumae, Yoshiyuki Sawai, Yasuharu Imai, Kazuyoshi Ohkawa, Masanori Miyazaki, Satoshi Tanaka, Eiji Mita, Seiichi Tawara, Takayuki Yakushijin, Yasutoshi Nozaki, Hideki Hagiwara, Yuki Tahata, Ryoko Yamada, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Published 2022-02-01
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Liver Fibrosis Is Associated With Corrected QT Prolongation During Ledipasvir/Sofosbuvir Treatment for Patients With Chronic Hepatitis C by Yuki Tahata, Ryotaro Sakamori, Ayako Urabe, Naoki Morishita, Ryoko Yamada, Takayuki Yakushijin, Naoki Hiramatsu, Yoshinori Doi, Akira Kaneko, Hideki Hagiwara, Yukinori Yamada, Taizo Hijioka, Masami Inada, Shinji Tamura, Yasuharu Imai, Kunimaro Furuta, Takahiro Kodama, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Published 2018-08-01
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Fucosylated haptoglobin is a novel predictive marker of hepatocellular carcinoma after hepatitis C virus elimination in patients with advanced liver fibrosis. by Kumiko Shirai, Hayato Hikita, Ryotaro Sakamori, Akira Doi, Yuki Tahata, Sadatsugu Sakane, Yoshihiro Kamada, Kazuhiro Murai, Akira Nishio, Ryoko Yamada, Takahiro Kodama, Yasutoshi Nozaki, Naruyasu Kakita, Hisashi Ishida, Fumihiko Nakanishi, Naoki Morishita, Kazuho Imanaka, Mitsuru Sakakibara, Tomohide Tatsumi, Eiji Miyoshi, Tetsuo Takehara
Published 2022-01-01
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Thrombospondin-2 as a Predictive Biomarker for Hepatocellular Carcinoma after Hepatitis C Virus Elimination by Direct-Acting Antiviral by Takayuki Matsumae, Takahiro Kodama, Yuki Tahata, Yuta Myojin, Akira Doi, Akira Nishio, Ryoko Yamada, Yasutoshi Nozaki, Masahide Oshita, Naoki Hiramatsu, Naoki Morishita, Kazuyoshi Ohkawa, Taizo Hijioka, Mitsuru Sakakibara, Yoshinori Doi, Naruyasu Kakita, Takayuki Yakushijin, Ryotaro Sakamori, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Published 2023-01-01
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Hepatitis B surface antigen reduction is associated with hepatitis B core-specific CD8+ T cell quality by Shokichi Takahama, Sachiyo Yoshio, Yuji Masuta, Hirotomo Murakami, Hirotomo Murakami, Ryotaro Sakamori, Shun Kaneko, Shun Kaneko, Takashi Honda, Miyako Murakawa, Masaya Sugiyama, Masayuki Kurosaki, Yasuhiro Asahina, Yasuhiro Asahina, Tetsuo Takehara, Victor Appay, Victor Appay, Tatsuya Kanto, Takuya Yamamoto, Takuya Yamamoto, Takuya Yamamoto, Takuya Yamamoto
Published 2023-10-01
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Use of Mac‐2 binding protein as a biomarker for nonalcoholic fatty liver disease diagnosis by Yoshihiro Kamada, Masafumi Ono, Hideyuki Hyogo, Hideki Fujii, Yoshio Sumida, Makoto Yamada, Kojiroh Mori, Saiyu Tanaka, Tomohiro Maekawa, Yusuke Ebisutani, Akiko Yamamoto, Shinji Takamatsu, Masashi Yoneda, Norifumi Kawada, Kazuaki Chayama, Toshiji Saibara, Tetsuo Takehara, Eiji Miyoshi, Japan Study Group of Nonalcoholic Fatty Liver Disease (JSG‐NAFLD)
Published 2017-10-01
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Circulating Cell-Free DNA Profiling Predicts the Therapeutic Outcome in Advanced Hepatocellular Carcinoma Patients Treated with Combination Immunotherapy by Takayuki Matsumae, Takahiro Kodama, Yuta Myojin, Kazuki Maesaka, Ryotaro Sakamori, Ayako Takuwa, Keiko Oku, Daisuke Motooka, Yoshiyuki Sawai, Masahide Oshita, Tasuku Nakabori, Kazuyoshi Ohkawa, Masanori Miyazaki, Satoshi Tanaka, Eiji Mita, Seiichi Tawara, Takayuki Yakushijin, Yasutoshi Nozaki, Hideki Hagiwara, Yuki Tahata, Ryoko Yamada, Hayato Hikita, Tomohide Tatsumi, Tetsuo Takehara
Published 2022-07-01
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