Leveraging on past investment in understanding the immunology of COVID-19 – the South African experience by Thandeka Moyo-Gwete, Penny L. Moore

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Dependence on a variable residue limits the breadth of an HIV MPER neutralizing antibody, despite convergent evolution with broadly neutralizing antibodies. by Cathrine Scheepers, Prudence Kgagudi, Nonkululeko Mzindle, Elin S Gray, Thandeka Moyo-Gwete, Bronwen E Lambson, Brent Oosthuysen, Batsirai Mabvakure, Nigel J Garrett, Salim S Abdool Karim, Lynn Morris, Penny L Moore

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Enhanced neutralization potency of an identical HIV neutralizing antibody expressed as different isotypes is achieved through genetically distinct mechanisms by Thandeka Moyo-Gwete, Cathrine Scheepers, Zanele Makhado, Prudence Kgagudi, Nonkululeko B. Mzindle, Rutendo Ziki, Sharon Madzorera, Nelia P. Manamela, Frances Ayres, Bronwen E. Lambson, Simone I. Richardson, Lynn Morris, Penny L. Moore

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Despite delayed kinetics, people living with HIV achieve equivalent antibody function after SARS-CoV-2 infection or vaccination by Boitumelo M. Motsoeneng, Boitumelo M. Motsoeneng, Nelia P. Manamela, Nelia P. Manamela, Haajira Kaldine, Haajira Kaldine, Prudence Kgagudi, Prudence Kgagudi, Tandile Hermanus, Tandile Hermanus, Frances Ayres, Frances Ayres, Zanele Makhado, Zanele Makhado, Thandeka Moyo-Gwete, Thandeka Moyo-Gwete, Mieke A. van der Mescht, Fareed Abdullah, Fareed Abdullah, Michael T. Boswell, Veronica Ueckermann, Theresa M. Rossouw, Shabir A. Madhi, Shabir A. Madhi, Shabir A. Madhi, Penny L. Moore, Penny L. Moore, Penny L. Moore, Simone I. Richardson, Simone I. Richardson

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Rapid and Successful Implementation of a COVID-19 Convalescent Plasma Programme—The South African Experience by Tanya Nadia Glatt, Caroline Hilton, Cynthia Nyoni, Avril Swarts, Ronel Swanevelder, James Cowley, Cordelia Mmenu, Thandeka Moyo-Gwete, Penny L. Moore, Munzhedzi Kutama, Jabulisile Jaza, Itumeleng Phayane, Tinus Brits, Johan Koekemoer, Ute Jentsch, Derrick Nelson, Karin van den Berg, Marion Vermeulen

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SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021 by Jonathan Mandolo, Jacquline Msefula, Marc Y. R. Henrion, Comfort Brown, Brewster Moyo, Aubrey Samon, Thandeka Moyo-Gwete, Zanele Makhado, Frances Ayres, Thopisang Motlou, Nonkululeko Mzindle, Newton Kalata, Adamson S. Muula, Gaurav Kwatra, Natasha Nsamala, Andrew Likaka, Thom Mfune, Penny L. Moore, Bridon Mbaya, Neil French, Robert S. Heyderman, Todd Swarthout, Kondwani C. Jambo

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AstraZeneca COVID-19 vaccine induces robust broadly cross-reactive antibody responses in Malawian adults previously infected with SARS-CoV-2 by Marah G. Chibwana, Thandeka Moyo-Gwete, Gaurav Kwatra, Jonathan Mandolo, Tandile Hermanaus, Thopisang Motlou, Nonkululeko Mzindle, Frances Ayres, Mphatso Chaponda, Godwin Tembo, Percy Mwenechanya, Ndaona Mitole, Chisomo Jassi, Raphael Kamng’ona, Louise Afran, David Mzinza, Henry C. Mwandumba, Stephen B. Gordon, Khuzwayo Jere, Shabir Madhi, Penny L. Moore, Robert S. Heyderman, Kondwani C. Jambo

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Infection pre-Ad26.COV2.S-vaccination primes greater class switching and reduced CXCR5 expression by SARS-CoV-2-specific memory B cells by Robert G. E. Krause, Thandeka Moyo-Gwete, Simone I. Richardson, Zanele Makhado, Nelia P. Manamela, Tandile Hermanus, Nonhlanhla N. Mkhize, Roanne Keeton, Ntombi Benede, Mathilda Mennen, Sango Skelem, Farina Karim, Khadija Khan, Catherine Riou, Ntobeko A. B. Ntusi, Ameena Goga, Glenda Gray, Willem Hanekom, Nigel Garrett, Linda-Gail Bekker, Andreas Groll, Alex Sigal, Penny L. Moore, Wendy A. Burgers, Alasdair Leslie

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Homologous Ad26.COV2.S vaccination results in reduced boosting of humoral responses in hybrid immunity, but elicits antibodies of similar magnitude regardless of prior infection. by Thandeka Moyo-Gwete, Simone I Richardson, Roanne Keeton, Tandile Hermanus, Holly Spencer, Nelia P Manamela, Frances Ayres, Zanele Makhado, Thopisang Motlou, Marius B Tincho, Ntombi Benede, Amkele Ngomti, Richard Baguma, Masego V Chauke, Mathilda Mennen, Marguerite Adriaanse, Sango Skelem, Ameena Goga, Nigel Garrett, Linda-Gail Bekker, Glenda Gray, Ntobeko A B Ntusi, Catherine Riou, Wendy A Burgers, Penny L Moore

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Distinct T cell polyfunctional profile in SARS-CoV-2 seronegative children associated with endemic human coronavirus cross-reactivity by Ntombi Benede, Marius B. Tincho, Avril Walters, Vennesa Subbiah, Amkele Ngomti, Richard Baguma, Claire Butters, Lina Hahnle, Mathilda Mennen, Sango Skelem, Marguerite Adriaanse, Heidi Facey-Thomas, Christiaan Scott, Jonathan Day, Timothy F. Spracklen, Strauss van Graan, Sashkia R. Balla, Thandeka Moyo-Gwete, Penny L. Moore, Rae MacGinty, Maresa Botha, Lesley Workman, Marina Johnson, David Goldblatt, Heather J. Zar, Ntobeko A.B. Ntusi, Liesl Zühlke, Kate Webb, Catherine Riou, Wendy A. Burgers, Roanne S. Keeton

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Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants. by Catherine Riou, Jinal N Bhiman, Yashica Ganga, Shobna Sawry, Frances Ayres, Richard Baguma, Sashkia R Balla, Ntombi Benede, Mallory Bernstein, Asiphe S Besethi, Sandile Cele, Carol Crowther, Mrinmayee Dhar, Sohair Geyer, Katherine Gill, Alba Grifoni, Tandile Hermanus, Haajira Kaldine, Roanne S Keeton, Prudence Kgagudi, Khadija Khan, Erica Lazarus, Jean Le Roux, Gila Lustig, Mashudu Madzivhandila, Siyabulela F J Magugu, Zanele Makhado, Nelia P Manamela, Qiniso Mkhize, Paballo Mosala, Thopisang P Motlou, Hygon Mutavhatsindi, Nonkululeko B Mzindle, Anusha Nana, Rofhiwa Nesamari, Amkele Ngomti, Anathi A Nkayi, Thandeka P Nkosi, Millicent A Omondi, Ravindre Panchia, Faeezah Patel, Alessandro Sette, Upasna Singh, Strauss van Graan, Elizabeth M Venter, Avril Walters, Thandeka Moyo-Gwete, Simone I Richardson, Nigel Garrett, Helen Rees, Linda-Gail Bekker, Glenda Gray, Wendy A Burgers, Alex Sigal, Penny L Moore, Lee Fairlie

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