Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study Por Joanna Lankester, Daniela Zanetti, Erik Ingelsson, Themistocles L. Assimes

Obter o texto integral

Associations between a Genetic Risk Score for Clinical CAD and Early Stage Lesions in the Coronary Artery and the Aorta. Por Elias L Salfati, David M Herrington, Themistocles L Assimes

Obter o texto integral

Alcohol use and cardiometabolic risk in the UK Biobank: A Mendelian randomization study. Por Joanna Lankester, Daniela Zanetti, Erik Ingelsson, Themistocles L Assimes

Obter o texto integral

Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort Por Wangjing Ke, Kristin A. Rand, David V. Conti, Veronica W. Setiawan, Daniel O. Stram, Lynne Wilkens, Loic Le Marchand, Themistocles L. Assimes, Themistocles L. Assimes, Christopher A. Haiman

Obter o texto integral

Large‐Scale Plasma Protein Profiling of Incident Myocardial Infarction, Ischemic Stroke, and Heart Failure Por Lars Lind, Daniela Zanetti, Martin Ingelsson, Stefan Gustafsson, Johan Ärnlöv, Themistocles L. Assimes

Obter o texto integral

Plasma proteomics and carotid intima-media thickness in the UK biobank cohort Por Ming-Li Chen, Pik Fang Kho, Rodrigo Guarischi-Sousa, Rodrigo Guarischi-Sousa, Jiayan Zhou, Daniel J. Panyard, Zahra Azizi, Trisha Gupte, Kathleen Watson, Fahim Abbasi, Fahim Abbasi, Themistocles L. Assimes, Themistocles L. Assimes

Obter o texto integral

Long-term use of angiotensin receptor blockers and the risk of cancer. Por Laurent Azoulay, Themistocles L Assimes, Hui Yin, Dorothee B Bartels, Ernesto L Schiffrin, Samy Suissa

Obter o texto integral

Associations between accurate measures of adiposity and fitness, blood proteins, and insulin sensitivity among South Asians and Europeans Por Pik Fang Kho, Pik Fang Kho, Laurel Stell, Shirin Jimenez, Shirin Jimenez, Daniela Zanetti, Daniela Zanetti, Daniela Zanetti, Daniel J. Panyard, Kathleen L. Watson, Ashish Sarraju, Ashish Sarraju, Ming-Li Chen, Ming-Li Chen, Lars Lind, John R. Petrie, Khin N. Chan, Holly Fonda, Kyla Kent, Kyla Kent, Jonathan N. Myers, Jonathan N. Myers, Jonathan N. Myers, Latha Palaniappan, Latha Palaniappan, Latha Palaniappan, Fahim Abbasi, Themistocles L. Assimes, Themistocles L. Assimes, Themistocles L. Assimes, Themistocles L. Assimes

Obter o texto integral

Mendelian randomization analyses clarify the effects of height on cardiovascular diseases. Por Daniel Hui, Eric Sanford, Kimberly Lorenz, Scott M Damrauer, Themistocles L Assimes, Christopher S Thom, Benjamin F Voight

Obter o texto integral

Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensiti... Por Karlijn A. C. Meeks, Amy R. Bentley, Themistocles L. Assimes, Nora Franceschini, Adebowale A. Adeyemo, Charles N. Rotimi, Ayo P. Doumatey

Obter o texto integral

Broad clinical manifestations of polygenic risk for coronary artery disease in the Women’s Health Initiative Por Shoa L. Clarke, Matthew Parham, Joanna Lankester, Aladdin H. Shadyab, Simin Liu, Charles Kooperberg, JoAnn E. Manson, Catherine Tcheandjieu, Themistocles L. Assimes

Obter o texto integral

Genetic Loci Associated With COVID-19 Positivity and Hospitalization in White, Black, and Hispanic Veterans of the VA Million Veteran Program Por Gina M. Peloso, Gina M. Peloso, Catherine Tcheandjieu, Catherine Tcheandjieu, Catherine Tcheandjieu, John E. McGeary, John E. McGeary, Daniel C. Posner, Yuk-Lam Ho, Jin J. Zhou, Jin J. Zhou, Austin T. Hilliard, Jacob Joseph, Jacob Joseph, Jacob Joseph, Christopher J. O’Donnell, Christopher J. O’Donnell, Christopher J. O’Donnell, Jimmy T. Efird, Dana C. Crawford, Dana C. Crawford, Dana C. Crawford, Dana C. Crawford, Wen-Chih Wu, Wen-Chih Wu, Mehrdad Arjomandi, Mehrdad Arjomandi, VA Million Veteran Program COVID-19 Science Initiative, Yan V. Sun, Yan V. Sun, Themistocles L Assimes, Themistocles L Assimes, Themistocles L Assimes, Jennifer E. Huffman

Obter o texto integral

Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study Por Ming-Li Chen, Jin Li, Kruthika R. Iyer, Catherine Tcheandjieu, Shirin Jimenez, Elias Levy Itshak Salfati, Liana C. Del Gobbo, Marcia L Stefanick, Manisha Desai, Xiaonan Xue, Themistocles L Assimes

Obter o texto integral

Multi-trait association studies discover pleiotropic loci between Alzheimer’s disease and cardiometabolic traits Por William P. Bone, Katherine M. Siewert, Anupama Jha, Derek Klarin, Scott M. Damrauer, The VA Million Veteran Program, Kyong-Mi Chang, Philip S. Tsao, Themistocles L. Assimes, Marylyn D. Ritchie, Benjamin F. Voight

Obter o texto integral

Interactions of physical activity, muscular fitness, adiposity, and genetic risk for NAFLD Por Theresia M. Schnurr, Sophia Figueroa Katz, Johanne M. Justesen, Jack W. O’Sullivan, Peter Saliba‐Gustafsson, Themistocles L. Assimes, Ivan Carcamo‐Orive, Aijaz Ahmed, Euan A. Ashley, Torben Hansen, Joshua W. Knowles

Obter o texto integral

Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation. Por Clint L Miller, Ulrike Haas, Roxanne Diaz, Nicholas J Leeper, Ramendra K Kundu, Bhagat Patlolla, Themistocles L Assimes, Frank J Kaiser, Ljubica Perisic, Ulf Hedin, Lars Maegdefessel, Heribert Schunkert, Jeanette Erdmann, Thomas Quertermous, Georg Sczakiel

Obter o texto integral

Disease-related growth factor and embryonic signaling pathways modulate an enhancer of TCF21 expression at the 6q23.2 coronary heart disease locus. Por Clint L Miller, D Ryan Anderson, Ramendra K Kundu, Azad Raiesdana, Sylvia T Nürnberg, Roxanne Diaz, Karen Cheng, Nicholas J Leeper, Chung-Hsing Chen, I-Shou Chang, Eric E Schadt, Chao Agnes Hsiung, Themistocles L Assimes, Thomas Quertermous

Obter o texto integral

Polygenic Risk Score Identifies Patients at Increased Risk for Abdominal Aortic Aneurysm and May Benefit from Ultrasound Screening Por Derek Klarin, Ozan Dikilitas, Brooke Wolford, Michael Levin, Ishan Paranjpe, Renae Judy, Julie Lynch, Themistocles L. Assimes, Yan Sun, Daniel Rader, Peter W. Wilson, Salvatore Scali, Scott Berceli, Sekar Kathiresan, Pradeep Natarajan, Girish Nadkarni, Cristen Willer, Iftikhar Kullo, Scott M. Damrauer, Philip Tsao

Obter o texto integral

Integrative functional genomics identifies regulatory mechanisms at coronary artery disease loci Por Clint L. Miller, Milos Pjanic, Ting Wang, Trieu Nguyen, Ariella Cohain, Jonathan D. Lee, Ljubica Perisic, Ulf Hedin, Ramendra K. Kundu, Deshna Majmudar, Juyong B. Kim, Oliver Wang, Christer Betsholtz, Arno Ruusalepp, Oscar Franzén, Themistocles L. Assimes, Stephen B. Montgomery, Eric E. Schadt, Johan L.M. Björkegren, Thomas Quertermous

Obter o texto integral

Association of the transthyretin variant V122I with polyneuropathy among individuals of African ancestry Por Margaret M. Parker, Scott M. Damrauer, Catherine Tcheandjieu, David Erbe, Emre Aldinc, Philip N. Hawkins, Julian D. Gillmore, Leland E. Hull, Julie A. Lynch, Jacob Joseph, Simina Ticau, Alexander O. Flynn-Carroll, Aimee M. Deaton, Lucas D. Ward, Themistocles L. Assimes, Philip S. Tsao, Kyong-Mi Chang, Daniel J. Rader, Kevin Fitzgerald, Akshay K. Vaishnaw, Gregory Hinkle, Paul Nioi

Obter o texto integral