The bone–muscle connection in breast cancer: implications and therapeutic strategies to preserve musculoskeletal health by Tarah J. Ballinger, William R. Thompson, Theresa A. Guise

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The Role of TGF-β in Bone Metastases by Trupti Trivedi, Gabriel M. Pagnotti, Theresa A. Guise, Khalid S. Mohammad

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Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model by Jenna N. Regan, Carter Mikesell, Steven Reiken, Haifang Xu, Andrew R. Marks, Khalid S. Mohammad, Theresa A. Guise, David L. Waning

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#49. Complete estrogen-deprived athymic nude mice are susceptible to changes in metabolism and musculoskeletal function mediated by a high-fat diet by Trupti Trivedi, Gabriel M. Pagnotti, Sukanya Suresh, Yun She, Sreemala Murthy, Jade Martinez, Carmella-Evans Molina, Khalid S. Mohammad, Theresa A. Guise

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Bone-derived excess TGF-ß release is associated with cognitive dysfunction due to oxidation of RyR, Ca2+ leak and mitochondrial dysfunction by Lei Shi, Sukanya Suresh, Truc Kuo, Anand Singh, Jade Martinez, Trupti Trivedi, Gabriel M. Pagnotti, Leah D. Guerra, Xu Cao, Theresa A. Guise

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RANKL/RANK/MMP-1 molecular triad contributes to the metastatic phenotype of breast and prostate cancer cells in vitro. by Sandra Casimiro, Khalid S Mohammad, Ricardo Pires, Joana Tato-Costa, Irina Alho, Rui Teixeira, António Carvalho, Sofia Ribeiro, Allan Lipton, Theresa A Guise, Luis Costa

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#5. Activating RET mutations in medullary thyroid cancer cells promotes osteoblastic bone metastasis by inhibiting osteoclastogenesis and stimulating osteoblast activity by Rozita Bagheri-Yarmand, Gabriel M Pagnotti, Trupti Trivedi, Leah Guerra, Joseph L. Kidd, Jade A. Martinez, Jian H. Song, Sua-Hwa Lin, Theresa A. Guise

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Hypoxia and TGF-beta drive breast cancer bone metastases through parallel signaling pathways in tumor cells and the bone microenvironment. by Lauren K Dunn, Khalid S Mohammad, Pierrick G J Fournier, C Ryan McKenna, Holly W Davis, Maria Niewolna, Xiang Hong Peng, John M Chirgwin, Theresa A Guise

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Osteocyte CIITA aggravates osteolytic bone lesions in myeloma by Huan Liu, Jin He, Rozita Bagheri-Yarmand, Zongwei Li, Rui Liu, Zhiming Wang, Duc-hiep Bach, Yung-hsing Huang, Pei Lin, Theresa A. Guise, Robert F. Gagel, Jing Yang

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c-Fms signaling mediates neurofibromatosis Type-1 osteoclast gain-in-functions. by Yongzheng He, Steven D Rhodes, Shi Chen, Xiaohua Wu, Jin Yuan, Xianlin Yang, Li Jiang, Xianqi Li, Naoyuki Takahashi, Mingjiang Xu, Khalid S Mohammad, Theresa A Guise, Feng-Chun Yang

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Molecular and clinical effects of aromatase inhibitor therapy on skeletal muscle function in early-stage breast cancer by Tara A. Seibert, Lei Shi, Sandra Althouse, Richard Hoffman, Bryan P. Schneider, Kristen A. Russ, Cody A. Altherr, Stuart J. Warden, Theresa A. Guise, Andrew R. Coggan, Tarah J. Ballinger

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Dystrophic spinal deformities in a neurofibromatosis type 1 murine model. by Steven D Rhodes, Wei Zhang, Dalong Yang, Hao Yang, Shi Chen, Xiaohua Wu, Xiaohong Li, Xianlin Yang, Khalid S Mohammad, Theresa A Guise, Amanda L Bergner, David A Stevenson, Feng-Chun Yang

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The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1. by Xiaohua Wu, Shi Chen, Yongzheng He, Steven D Rhodes, Khalid S Mohammad, Xiaohong Li, Xianlin Yang, Li Jiang, Grzegorz Nalepa, Paige Snider, Alexander G Robling, D Wade Clapp, Simon J Conway, Theresa A Guise, Feng-Chun Yang

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TG-interacting factor 1 (Tgif1)-deficiency attenuates bone remodeling and blunts the anabolic response to parathyroid hormone by Hiroaki Saito, Andreas Gasser, Simona Bolamperti, Miki Maeda, Levi Matthies, Katharina Jähn, Courtney L. Long, Hartmut Schlüter, Marcel Kwiatkowski, Vaibhav Saini, Paola Divieti Pajevic, Teresita Bellido, Andre J. van Wijnen, Khalid S. Mohammad, Theresa A. Guise, Hanna Taipaleenmäki, Eric Hesse

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Pharmacologic inhibition of the TGF-beta type I receptor kinase has anabolic and anti-catabolic effects on bone. by Khalid S Mohammad, Carol G Chen, Guive Balooch, Elizabeth Stebbins, C Ryan McKenna, Holly Davis, Maria Niewolna, Xiang Hong Peng, Daniel H N Nguyen, Sophi S Ionova-Martin, John W Bracey, William R Hogue, Darren H Wong, Robert O Ritchie, Larry J Suva, Rik Derynck, Theresa A Guise, Tamara Alliston

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